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Cleft Lip clinical trials

The registry lists 168 studies for Cleft Lip across more than 10 countries. 51 are recruiting or about to start. 141 of them are mainly about Cleft Lip (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Van der Woude syndrome too: 204 studies, 60 open.

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Status

Completed
74
Status unknown
29
Recruiting
28
Not yet recruiting
17
Terminated
7
Enrolling by invitation
6

Phase

Phase 2
8
Phase 3
6
Phase 1
5
Phase 4
4

Where

Egypt
46
United States
28
France
11
Brazil
8
Belgium
6
Taiwan
6

Who runs them

Cairo University (25) · Chang Gung Memorial Hospital (7) · Faculty of Dental Medicine for Girls (5) · Ain Shams University (5) · The University of Texas Health Science Center, Houston (5) · Assiut University (5) · University Ghent (4) · Alexandria University (4)

What is being tested here

Drugs under test in Cleft Lip studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Botulinum toxin type A103
Dexmedetomidine102
Ketorolac101
Nalbuphine101
Liposomal Bupivacaine111
Bupivacaine111
Dexamethasone001
Folic Acid011

Coming up

2phase 3 studies under way
16studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 28 Cleft Lip studies recruiting now, 8 (29%) set no upper age limit and 19 (68%) stop at 75 or younger. 26 (93%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (29%) take healthy volunteers.

Recruiting studies that take each age, of 28
AgeWomenMen
1020 (71%)20 (71%)
1814 (50%)14 (50%)
3010 (36%)10 (36%)
409 (32%)9 (32%)
509 (32%)9 (32%)
659 (32%)9 (32%)
759 (32%)9 (32%)
859 (32%)9 (32%)

Across all 168 studies, recruiting or not: 77% stop at 75 or younger and 77% at 65; 95% take children; 2% are for women only and 0% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Cleft Lip studies take

Of 65 interventional studies with no phase under Cleft Lip, half reached primary completion within 22 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase22 mo15–33 · 65 studies—22 mo15–33 · 64 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 168. Browse all 168 → or search them.