An observational study in Dental Age Estimation and Cleft Lip and Palate, sponsored by Istanbul University. Recruiting at 1 site in Turkey. Open to participants aged 5 Years to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-27.
Sponsored by Istanbul University · Observational
The aim of this study is to investigate whether there is a significant difference in dental age between children with CLP and healthy controls using the Willems method, Cameriere European formula and London Atlas. It is aimed to create a new formula if there is a significant difference in dental age between children with CLP and healthy controls.
Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan.
There are two basic approaches to dental age determination in children:
evaluation of eruption of teeth in the oral cavity, evaluation of the development and mineralization of crowns and roots on dental radiographs.
In many methods, the developmental stages of different numbers of permanent teeth are used.
The most commonly used method for determining dental age in children; is the Demirjian method that evaluates the development of seven left permanent mandibular teeth in eight stages (from A to H). Willems et al. In 2001, they modified the Demirjian method by conducting a study on the fact that it showed higher age determination in the Belgian Caucasian population. The adapted method was named the Willems method. It is stated that one of the advantages of this method is that it is a relatively simple system for determining tooth age.
One of the most widely used methods of dental age determination recently is the European formula of Cameriere et al., which is calculated based on open apex. It has been reported that this method has been tested on different population groups, and the results are accurate and reliable.
An atlas method was proposed by a group of London researchers in 2010. The Atlas shows all the teeth array images of certain age groups as a schematic series. Age determination is made by deciding which reference image matches the individual's panoramic radiography image more.
168 studies on the registry are indexed under Cleft Lip; 51 are open to participants now.
This study's planned enrollment of 240 is above the median of 100 across 49 observational studies indexed under Cleft Lip.
Browse Cleft Lip studies →Istanbul University is the lead sponsor of 511 studies on the registry; 78 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.
Counted across the registry records on this site, refreshed daily.
This study was conducted on gender-age matched healthy control group of children aged 5-14 years, who applied to Istanbul University Faculty of Dentistry, Department of Pedodontics, had an AI record in their anamnesis, had panoramic radiographs in the archive of the Department of Oral and Maxillofacial Radiology, Istanbul University Faculty of Dentistry.
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Exclusion Criteria:
Other: Diagnostic Test: Willems method · Other: Diagnostic Test: Cameriere method · Other: Diagnostic Test: London Atlas method
Other: Diagnostic Test: Willems method · Other: Diagnostic Test: Cameriere method · Other: Diagnostic Test: London Atlas method
Willems method measures the developmental stages of the seven left permanent mandibular teeth and is frequently used for dental age estimation. The score of each stage is allocated, and the sum of the scores provides an evaluation of the subject's dental maturity.
Cameriere et al. designed a quantitative approach through a formula based on sex and the ratio between length and apex opening measurements of each lower left tooth.
The London Atlas requires the user to assess the tooth development and eruption and then match it to one of the 31 pictures of age categories.
Correlation coefficient of Willems method
Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient
Time frame: day 1
Correlation coefficient of London Atlas method.
Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient.
Time frame: day 1
Correlation coefficient of Cameriere European formula.
Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient.
Time frame: day 1
Dental age estimation in children with Cleft Lip and Palate
Dental age estimation in Turkish children
Time frame: day 1
Plan to share: No
No publications or documents are linked to this record.
Started Mar 2022 (actual). Primary completion is estimated for Nov 2024, 32 months after the start.
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