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Congenital Abnormalities clinical trials

The registry lists 781 studies for Congenital Abnormalities across more than 10 countries. 77 are recruiting or about to start. 150 of them are mainly about Congenital Abnormalities (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 127 narrower conditions too, such as Heart Defects, Congenital: 7,929 studies, 1,884 open.

ClinicalTrials.gov finds 25,634 studies for Congenital Abnormalities. How that becomes 780 here

This page counts the studies the registry files under Congenital Abnormalities, and those it files under no condition that list Congenital Abnormalitiesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 25,634Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −6,750Filed under a narrower condition, counted on its own pageHeart Defects, Congenital 978 · Down Syndrome 429 · Arteriovenous Fistula 223 · Polycystic Kidney, Autosomal Dominant 184 · Neurofibromatosis 1 174 · Flatfoot 163 · 110 more
  3. −33List Congenital Abnormalities as a condition, but the registry did not file them under itMost often written as “Upper Extremity Deformities, Congenital” (3), “Lower Extremity Deformities, Congenital” (2), and “Jaw Deformity” (2). The registry filed 4 of them under no condition at all, and the others under other conditions only, most often Upper Extremity Deformities, Congenital (5) and Lower Extremity Deformities, Congenital (4).
  4. −18,071Match it another way12 name it in the title, 3 in a keyword, and 18,056 by a synonym or other text the search reads.
  5. 780The count on this page

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Status

Completed
487
Terminated
97
Status unknown
60
Recruiting
60
Active, not recruiting
32
Withdrawn
23

Phase

Phase 2
205
Phase 1
152
Phase 3
43
Phase 4
7
Early Phase 1
4

Where

United States
476
France
56
Canada
30
United Kingdom
29
Italy
25
China
25

Who runs them

National Cancer Institute (NCI) (58) · Fred Hutchinson Cancer Center (51) · Case Comprehensive Cancer Center (19) · City of Hope Medical Center (19) · Roswell Park Cancer Institute (17) · SWOG Cancer Research Network (14) · Masonic Cancer Center, University of Minnesota (13) · Wake Forest University Health Sciences (13)

What is being tested here

Drugs under test in Congenital Abnormalities studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Platelet rich plasma222
Tacrolimus1221
Antibodies, Monoclonal111
Episalvan111
Birch triterpenes111
Fludarabine0160
Cytarabine0356
Fludarabine phosphate0155
Cyclophosphamide0247
Busulfan0444

Drug classes tested here Calcineurin inhibitors 1 open · Antimetabolites 142 · Alkylating agents 84 · HDAC inhibitors 14 · Tyrosine kinase inhibitors (TKIs) 11

Coming up

5phase 3 studies under way
16studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 60 Congenital Abnormalities studies recruiting now, 27 (45%) set no upper age limit and 27 (45%) stop at 75 or younger. 35 (58%) take children under 18. 17 (28%) are for women only and 2 (3%) for men only; 22 (37%) take healthy volunteers.

Recruiting studies that take each age, of 60
AgeWomenMen
1028 (47%)27 (45%)
1849 (82%)37 (62%)
3040 (67%)28 (47%)
4042 (70%)28 (47%)
5037 (62%)26 (43%)
6535 (58%)26 (43%)
7533 (55%)23 (38%)
8531 (52%)21 (35%)

Across all 781 studies, recruiting or not: 43% stop at 75 or younger and 34% at 65; 46% take children; 13% are for women only and 2% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Congenital Abnormalities studies take

Of 29 phase 2 interventional studies under Congenital Abnormalities, half reached primary completion within 84 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 139 mo31–85 · 22 studies——
Phase 284 mo50–119 · 29 studies—84 mo50–119 · 26 studies
Interventional, no phase37 mo14–72 · 76 studies—37 mo14–71 · 71 studies
Observational49 mo23–193 · 97 studies32 mo17–48 · 22 studies83 mo32–270 · 75 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 781. Browse all 781 → or search them.