An interventional study of Microfat grafting in Cleft Lip and Nose, sponsored by Assiut University. Not yet recruiting. Open to participants aged 5 Years to 35 Years. Per ClinicalTrials.gov, last updated 2026-10-29.
Sponsored by Assiut University · Not applicable, Interventional, and Treatment
Aim of the work:
The study will be conducted to investigate the efficacy of microfat graftinig in cleft lip nasal deformities especially in young patients and those adults who don't need major correction after rhinoplasty.
Microfat grafting was used for the first time in 1880, in reconstructive surgery to correct facial deformities, to reconstruct defects post oncological surgery, to treat complex wounds, and to manage scars. Therefore its usage is increasing widely and particularly in maxillofacial and plastic surgeries.
As lipofilling is a potential filler of reference for rhinoplasty and it can be performed on the dorsum, radix, glabella, pre-maxilla, and nasal pyramid. The investigators are suggesting it's use in cleft lip nasal deformities in some special situations.
Imperfections post rhinoplasty are common and there is an increased risk of patient dissatisfaction in revision surgeries. This may be due to a change in the nasal anatomy, the development of scar tissue, the loss of cartilaginous support, the altered blood supply, and the compromised soft tissue envelope. Here comes the role of fat grafting which is a relatively simple and safe procedure to camouflage nose imperfections in filling the subcutaneous tissue, and in improving the skin quality post rhinoplasty.
Microfat grafting appears to be effective for correcting minor irregularities of nasal skin and may be appropriate for patients who cannot undergo revision rhinoplasty. It is also an effective salvage procedure for severely damaged skin of the nose. Injection of cryopreserved fat over several sessions is well accepted by patients because cryopreservation of excess harvested fat grafts for subsequent use makes repeated fat graft harvesting unnecessary. Microfat grafting is not a replacement for, but may be a complement to, modern rhinoplasty techniques.
168 studies on the registry are indexed under Cleft Lip; 51 are open to participants now.
This study's planned enrollment of 30 is close to the median of 30 across 116 interventional studies indexed under Cleft Lip.
Browse Cleft Lip studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Procedure: Microfat grafting
Microfat grafting in cleft lip nasal deformities
Anthropometric measurement for the nose in relation to face
Results would be depending on objective and subjective measures : \*Objective assessment by taking photos by anthropometric measurement for the nose in relation to face.
Time frame: 6 months
patient and thier parents satisfaction
\*Subjective assessment by evaluate patients \& their parents satisfaction from the result From zero to 4 as : Zero = not satisfied 1. = fair satisfaction 2. = good 3. = very good 4. = fully satisfied Higher scores means better
Time frame: 6 months
No study locations are listed for this record.
Start is estimated for May 2027; primary completion for May 2027, 0 months later.
Of 64 non-industry interventional studies with no phase under Cleft Lip, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 15 and three quarters within 33. This study's planned 0 months is below that.
Counting every sponsor, half of 65 studies reached it within 22 months; a quarter within 15 and three quarters within 33.
Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 29, 2026: start May 2025 → May 2027, primary completion May 2025 → May 2027 and completion Oct 2025 → Oct 2027.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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