DrugSupplement
Folic Acid clinical trials
Also written vitamin B9 and Folacin.
- studies test it
- 179
- open now
- 22
- in phase 3
- 29
- first study started
- 1992
Keep track of what changes. Save the Folic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
173 studies that test it; most in 2008 (12)
| Year | Studies |
|---|---|
| 1992 | 1 |
| 1993 | 1 |
| 1995 | 2 |
| 1996 | 4 |
| 1997 | 1 |
| 1998 | 2 |
| 1999 | 1 |
| 2001 | 4 |
| 2002 | 2 |
| 2003 | 4 |
| 2004 | 9 |
| 2005 | 10 |
| 2006 | 2 |
| 2007 | 7 |
| 2008 | 12 |
| 2009 | 6 |
| 2010 | 8 |
| 2011 | 7 |
| 2012 | 6 |
| 2013 | 7 |
| 2014 | 7 |
| 2015 | 5 |
| 2016 | 4 |
| 2017 | 5 |
| 2018 | 5 |
| 2019 | 5 |
| 2020 | 4 |
| 2021 | 3 |
| 2022 | 9 |
| 2023 | 9 |
| 2024 | 8 |
| 2025 | 7 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 16
- Phase 2
- 45
- Phase 3
- 29
- Phase 4
- 37
- No phase
- 65
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 20 · Other 159
AGUNCO Obstetrics and Gynecology Centre (5) · Shenzhen Ausa Pharmed Co.,Ltd (5) · University of Alabama at Birmingham (4) · Centers for Disease Control and Prevention (4) · Harvard School of Public Health (HSPH) (3) · University of Oxford (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · The University of Hong Kong (3)
Often tested with
Tested in the same studies.
Vitamin B 12 (24) · Inositol (14) · Iron (11) · Pyridoxine (7) · Vitamin B 6 (5) · Enalapril (5) · Metformin (4) · B12 (4)
Studies
Open first, then newest update. How each study uses Folic Acid is read from its arms, and is right about nine times in ten.
Testing it · 179
- Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant WomenRecruitingNot applicableIBSA Farmaceutici Italia SrlNCT07884617Written as Iron plus folic acid
- Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOSRecruitingNot applicableDicle UniversityNCT07770711Written as Folic Acid
- Safety and Efficacy of Folic Acid Combined With Atezolizumab and Bevacizumab as First-Line Therapy for Unresectable Hepatocellular CarcinomaNot yet recruitingPhase 1/2West China HospitalNCT07835737Written as Folic Acid
- Prospective Management of Plaque Instability With Statins and Extra Folic AcidRecruitingPhase 1/2Ruijin HospitalNCT07680595Written as Atorvastatin plus folic acid
- Neurovascular Transduction During Exercise in Chronic Kidney DiseaseRecruitingPhase 2Emory UniversityNCT02947750Written as Folic acid
- Mitigation Efforts in Arsenic Exposure With Folic Acid SupplementationEnrolling by invitationNot applicableUniversity of Alabama at BirminghamNCT05656664Written as Folic Acid
- Folate Treatment to Reduce Death Risk in the Year After Infection-Related Acute Kidney InjuryNot yet recruitingEarly Phase 1The University of Hong KongNCT07377071Written as Folic Acid 5 MG
- Growth Hormone and Dehydroepiandrosterone Role in Vitro FertilizationRecruitingPhase 2/3Beni-Suef UniversityNCT07323329Written as DHEA plus folic acid 400mcg per day
- ICOPE INTENSE-K Pilot StudyRecruitingNot applicableUniversity Hospital, ToulouseNCT07048860Written as vitamin B9
- Feasibility Test of Folic Acid on Acute Kidney InjuryNot yet recruitingEarly Phase 1The University of Hong KongNCT07013136Written as Folic Acid 5 MG
- China Stroke Primary Prevention Trial 2 for Participants with H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT)RecruitingPhase 4Shenzhen Ausa Pharmed Co.,LtdNCT04974138Written as Amlodipine besylate and folic acid
- China Stroke Primary Prevention Trial 2 for Participants with Hypertension and MTHFR 677 TT GenotypeRecruitingPhase 4Shenzhen Ausa Pharmed Co.,LtdNCT04974151Written as Amlodipine besylate And Folic Acid
- Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's DiseaseRecruitingNot applicableOregon Health and Science UniversityNCT06772220Written as Folic Acid 1 MG
- Possible Action of Resveratrol in Improving the Outcomes of IVF/ICSI in Couples With Unexplained InfertilityRecruitingNot applicableAndros Day Surgery ClinicNCT06481696Written as Folic acid
- Folic Acid Supplementation to Reduce Anemia in Extremely Preterm InfantsNot yet recruitingNot applicableUniversity of CalgaryNCT06220461Written as Folic acid
- Effect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia TraitNot yet recruitingNot applicableThe University of Hong KongNCT04310059Written as Folic acid
- Effect of Folic Acid in Levodopa Treated Parkinson's Disease PatientsRecruitingPhase 2Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNCT05959044Written as Folic Acid Tablet
- Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA FormationNot yet recruitingNot applicableUniversity of British ColumbiaNCT01687127Written as Folic acid
- Folic Acid Supplementation in Calcific Aortic Valve DiseaseNot yet recruitingPhase 2Wuhan Union Hospital, ChinaNCT05861648Written as Folic Acid Oral Tablet
- Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC DetectionNot yet recruitingPhase 2Liaoning Cancer Hospital & InstituteNCT05720559Written as Folic acid
See all 179 studies that test Folic Acid →
Given in every arm · 75 — Folic Acid is usual care beside what is tested
- Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS PatientsRecruitingPhase 3Beni-Suef UniversityNCT07630779Written as Folic Acid
- Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast DiseaseNot yet recruitingPhase 4National University Hospital, SingaporeNCT06943482Written as Folic Acid 5 MG
- Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC PatientsActive, not recruitingPhase 2Shanghai Chest HospitalNCT05751187Written as Folic acid 350-1000 μg
- Methotrexate in Erosive Inflammatory Hand OsteoarthritisActive, not recruitingPhase 4Diakonhjemmet HospitalNCT04579848Written as Folic Acid 1 MG
- Intrathecal Pemetrexed for Leptomeningeal MetastasisCompletedPhase 1/2The First Hospital of Jilin UniversityNCT05289908Written as Folic Acid
- Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLCTerminatedPhase 3Checkpoint Therapeutics, Inc.NCT04786964Written as Folic acid 350-1000 μg
- Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)CompletedPhase 3Merck Sharp & Dohme LLCNCT02578680Written as Folic acid 350-1000 μg
- Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled GoutCompletedPhase 4AmgenNCT03994731Written as folic acid
- Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled GoutCompletedPhase 4AmgenNCT03635957Written as Folic Acid
- Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension StudyCompletedPhase 3Merck Sharp & Dohme LLCNCT03950674Written as Folic acid 350-1000 μg
- Perioperative Immunotherapy vs. Chemo-immunotherapy in Patients With Advanced GC and AEGActive, not recruitingPhase 2University Hospital, EssenNCT04062656Written as Folic acid (FA)
- Hydroxychloroquine in Prevention of PreeclampsiaCompletedNot applicableAssiut UniversityNCT04755322Written as Folic acid
- Hydroxychloroquine and Unexplained Recurrent MiscarriageCompletedNot applicableAssiut UniversityNCT04228263Written as Folic Acid
- Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis RemissionCompletedPhase 3AmgenNCT02373813Written as Folic acid (non-investigational product)
- Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer PatientsStatus unknownPhase 1NSABP Foundation IncNCT03626922Written as Folic Acid
- Efficacy of Lipid-Based Nutrient Supplements (LNS) for Pregnant and Lactating Women and Their InfantsCompletedNot applicableUniversity of California, DavisNCT00970866Written as Iron and Folic Acid (IFA)
- Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to MethotrexateCompletedPhase 2AmgenNCT00950989Written as folic acid
- Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's LymphomaCompletedPhase 2Spectrum Pharmaceuticals, IncNCT00998946Written as Folic Acid
- Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV MedicationsCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT01949116Written as Folic acid
- Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate MonotherapyTerminatedPhase 3Jawaharlal Institute of Postgraduate Medical Education & ResearchNCT02930343Written as Folic Acid
Showing 20 of 75.
As the comparator · 20 — what is tested is compared with Folic Acid
- Efficacy and Safety of Weifuchun Tablet in Reversing Gastric Intestinal MetaplasiaRecruitingPhase 4Yongquan ShiNCT06610266Written as Folic Acid
- The Impact of Myo-Inositol on Glycemic Control and Oxidative Stress in Gestational Diabetes MellitusRecruitingNot applicableMedical University of ViennaNCT07685015Written as Folic acid 200 µg
- Effect of Zinc Supplementation on Hyperhomocysteinemia Compared to Folic Acid in CKD Patient on HemodialysisRecruitingNot applicableChittagong Medical CollegeNCT06847139Written as Folic Acid 5 Mg Oral Tablet
- PREconception Folic Acid Clinical Efficacy (PREFACE) TrialNot yet recruitingNot applicableUniversity of British ColumbiaNCT06641245Written as Folic Acid
- Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal CancerRecruitingPhase 2Lithuanian University of Health SciencesNCT05378919Written as Fluorouracil/folic acid
- Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child OutcomesCompletedNot applicableEmory UniversityNCT01665378Written as Iron and Folic Acid
- Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOSCompletedNot applicableKafrelsheikh UniversityNCT07779850Written as Folic Acid
- Comparison of The Effect of 5-MTHF and Folic Acid Supplementation in Increasing Red Blood Cell Folate in Pregnant WomenCompletedNot applicableDr. Soetomo General HospitalNCT06935630Written as Folic Acid
- Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)Active, not recruitingPhase 2/3SWOG Cancer Research NetworkNCT05096663Written as Folic Acid
- Metformin Efficacy and Safety for Gastric Intestinal MetaplasiaCompletedPhase 4Xijing Hospital of Digestive DiseasesNCT05288153Written as Folate
- Natural Folate vs. Synthetic Folic Acid in PregnancyCompletedNot applicableUniversity of British ColumbiaNCT04022135Written as Folic acid
- Jianpi Huoxue Recipe in Treating Gastric Premalignant LesionStatus unknownPhase 1/2Xiyuan Hospital of China Academy of Chinese Medical SciencesNCT03823248Written as Folic Acid Tablet
- 5-methyltetrahydrofolate Survival and Inflammation in ESRD PatientsCompletedNot applicableIRCCS Azienda Ospedaliero-Universitaria di BolognaNCT00626223Written as folic acid
- Biological Effects of Treatment With Resveratrol in ART PatientsCompletedNot applicableUniversity Of PerugiaNCT04386499Written as Folic acid
- Myo-inositol as Pretreatment in Hyperandrogenic PCOS PatientsStatus unknownPhase 3Universitair Ziekenhuis BrusselNCT03767569Written as Folic Acid
- IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in TanzaniaStatus unknownPhase 3Ifakara Health InstituteNCT02541708Written as Ferrous sulfate + folic acid
- Interventions for Moderate Malnutrition in PregnancyCompletedNot applicableWashington University School of MedicineNCT02120599Written as folic acid
- Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent AbortionCompletedPhase 2/3National Nutrition and Food Technology InstituteNCT01976676Written as folic Acid
- Bioavailability of Folic Acid Fortified BreadCompletedPhase 2University of British ColumbiaNCT01570088Written as Folic acid
- Inositol Stereoisomers to Treat Gestational DiabetesStatus unknownNot applicableUniversità degli Studi 'G. d'Annunzio' Chieti e PescaraNCT02097069Written as Folic acid
Codes
What other systems call Folic Acid · ClinicalTrials.gg INT007522
- MeSH (NLM) D005492Folic AcidConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 935E97BOY8FOLIC ACIDConfirmed FDA, NLM, Wikidata
- RxNorm 4511Confirmed FDA, Wikidata
- Wikidata Q127060folic acidConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C510Folic AcidOne source FDA
- DrugBank DB00158One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D005492 | Folic Acid | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 935E97BOY8 | FOLIC ACID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4511 | — | Confirmed FDA, Wikidata |
| Wikidata | Q127060 | folic acid | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C510 | Folic Acid | One source FDA |
| DrugBank | DB00158 | — | One source Wikidata |
Also registered as folate sodium (UNII 9P9W8GGU78 · RxNorm 1300473).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.