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SuspendedNCT07923500Updated Nov 6, 2026

The Prevalence of Chronic Pain Following Cryoanalgesia and the Nuss Procedure.

An observational study in Cryoanalgesia, Pain Management and Chronic Pain, sponsored by Pomeranian Medical University Szczecin. Suspended at 1 site in Poland. Open to participants aged 1 Year to 18 Years. Per ClinicalTrials.gov, last updated 2026-11-06.

Sponsored by Pomeranian Medical University Szczecin · Observational

Why this study was suspended
We completed data collection in our university and we are waiting for the collaborating universities.
Updated Nov 6, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
300
Ages
1 Year to 18 Years
Sex
All
01

Study summary

The aim of the study is to analyze the prevalence of chronic pain, including neuropathic pain following operations for funnel chest deformity of the anterior chest wall in children.

Read the detailed description

Pectus excavatum is the most common congenital deformity of the anterior chest wall. The minimally invasive repair of pectus excavatum (MIRPE), is the standard surgical treatment. Intraoperative intercostal nerve cryoanalgesia (INC) has emerged as an important advance in postoperative pain management after MIRPE, reducing opioid consumption and length of hospital stay. Potential complications of intercostal nerve cryoanalgesia include transient sensory disturbances (hypoesthesia and paresthesia), neuropathic pain, local hematoma formation, infection, and injury to adjacent structures. Most sensory abnormalities are temporary and resolve spontaneously within several months.

We conducted a prospective observational before-and-after cohort study. The aim of the study was to analyze the prevalence of chronic pain, including neuropathic pain following operations for funnel chest deformity of the anterior chest wall in children with and without cryoanalgesia.

02

Conditions studied

  • Cryoanalgesia
  • Pain Management
  • Chronic Pain
  • Funnel Chest
03

In context

Chronic Pain

3,227 studies on the registry are indexed under Chronic Pain; 729 are open to participants now.

This study's planned enrollment of 300 is above the median of 120 across 753 observational studies indexed under Chronic Pain.

Browse Chronic Pain studies →

Lead sponsor

Pomeranian Medical University Szczecin is the lead sponsor of 69 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Year to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients under 18 years of age diagnosed with funnel-shaped anterior chest wall deformity undergoing minimally invasive Nuss surgery.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • funnel chest deformity
  • Haller index above 3,25

Exclusion criteria

Exclusion Criteria:

  • Thoracic deformity other than funnel chest;
  • Advanced chronic respiratory or circulatory failure;
  • Emergency surgery or reoperation;
  • History of thoracotomy or thoracic surgery;
  • Mental impairment precluding communication with the patient or lack of consent for cryoanalgesia or regional analgesia;
  • History of allergy to local anaesthetic;
  • History of taking medication for chronic pain
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
300 participants (estimated)
Patient registry
No

Groups and cohorts

  • multimodal and cryoanalgesia (after group)
  • multimodal without cryoanalgesia (before group)

    Patients treated

06

What researchers measure

Primary outcomes

  1. chronic pain

    The primary outcome was the incidence of chronic postsurgical pain at 3 months after surgery.

    Time frame: at 3 months after surgery

Secondary outcomes

  1. neuropathic pain

    The incidence of neuropathic postsurgical pain at 3 months after surgery.

    Time frame: at 3 months after surgery.

07

Study locations

1 site
  • Pomeranian Medical University
    Szczecin, Wybierz Prowincję 71-252, Poland
08

References and documents

Individual participant data

Plan to share: Undecided — NC

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Oct 2025 (actual). Primary completion is estimated for Aug 2027, 22 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 2, 2026
First posted
Nov 6, 2026
StartActual
Oct 15, 2025
Primary completionEst.
Aug 31, 2027
CompletionEst.
Dec 31, 2027
Last update
Nov 6, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 6, 2026
Show all 1 update
  1. Nov 6, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07923500
Lead sponsor
Pomeranian Medical University Szczecin
Responsible party
Sponsor
First posted
Nov 6, 2026
Start date
Oct 15, 2025
Primary completion
Aug 31, 2027 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
Nov 6, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is suspended, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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