Cholelithiasis clinical trials
The registry lists 189 studies for Cholelithiasis across more than 10 countries. 42 are recruiting or about to start. 116 of them are mainly about Cholelithiasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Gallstones: 506 studies, 104 open.
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Who runs them
University of California, San Diego (3) · Zhejiang University (3) · University of Roma La Sapienza (3) · Sisli Hamidiye Etfal Training and Research Hospital (3) · Karolinska Institutet (2) · Helsinki University Central Hospital (2) · Samsun Education and Research Hospital (2) · Konya Meram State Hospital (2)
What is being tested here
Drugs under test in Cholelithiasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bupivacaine | 1 | 0 | 4 |
| Remimazolam | 1 | 0 | 2 |
| Labetalol | 1 | 0 | 1 |
| Ursodeoxycholic Acid | 0 | 1 | 3 |
| Ketamine | 0 | 0 | 2 |
| Lidocaine | 0 | 0 | 2 |
| Propofol | 0 | 0 | 1 |
| Ciprofol | 0 | 0 | 1 |
| Chenodeoxycholic Acid | 0 | 0 | 1 |
| Granisetron | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway · Sir Ganga Ram Hospital
- Nov 2026Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration · Sisli Hamidiye Etfal Training and Research Hospital
- Nov 2026Improvised Endobag vs Direct Gallbladder Extraction in Laparoscopic Cholecystectomy · Rawal Institute of Health Sciences Islamabad
- Dec 2026Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes · Muş Alparslan University
- Dec 2026Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study · Zhejiang University
- Dec 2026STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy · Helsinki University Central Hospital
- Dec 2026Percutaneous Cholangiopancreatoscopy Registry · Johns Hopkins University
- Dec 2026Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions · Changi General Hospital
- Dec 2026Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers. · Valenta Pharm JSC
- Jan 2027Rectointercostal Plane Block (RICPB) for Laparoscopic Cholecystectomy · Koç University
Who these studies take
Of the 30 Cholelithiasis studies recruiting now, 19 (63%) set no upper age limit and 8 (27%) stop at 75 or younger. 1 (3%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 25 (83%) | 25 (83%) |
| 30 | 28 (93%) | 28 (93%) |
| 40 | 28 (93%) | 28 (93%) |
| 50 | 28 (93%) | 28 (93%) |
| 65 | 25 (83%) | 25 (83%) |
| 75 | 22 (73%) | 22 (73%) |
| 85 | 21 (70%) | 21 (70%) |
Across all 189 studies, recruiting or not: 40% stop at 75 or younger and 25% at 65; 15% take children; 5% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cholelithiasis studies take
Of 58 interventional studies with no phase under Cholelithiasis, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo6–24 · 58 studies | — | 17 mo6–27 · 54 studies |
| Observational | 33 mo18–191 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Ultrasound-Guided Rectus Sheath Block Versus Local InfiltrationOct 16, 2026NCT07582029
Newly registered3
- Comparison of Postoperative Pain, Nausea, and Vomiting Between Veress Needle and Direct Trocar Entry in Laparoscopic CholecystectomyNov 9, 2026NCT07924254
- Electrosurgical Patterns and Learning Curve in Elective Laparoscopic CholecystectomyOct 22, 2026NCT07888491
- Hasson Versus Veress Access With Umbilical Versus Epigastric Gallbladder Extraction in Laparoscopic CholecystectomyOct 21, 2026NCT07887139
Studies
Recruiting first, then most recently updated. Showing 50 of 189. Browse all 189 → or search them.
- Two Bupivacaine Concentrations for Recto-Intercostal Fascial Plane Block After Laparoscopic CholecystectomyNot yet recruitingNCT07841951Not applicable1 country
- Timing of CHolecystectomy In Severe PAncreatitisRecruitingNCT06113419Not applicable1 country
- Electrosurgical Patterns and Learning Curve in Elective Laparoscopic CholecystectomyRecruitingNCT078884911 country
- Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic CholecystectomyRecruitingNCT07717684Phase 41 country
- Ultrasound-Guided Rectus Sheath Block Versus Local InfiltrationRecruitingNCT07582029Not applicable1 country
- Effects of Postoperative Video-assisted Early Mobilization on Recovery OutcomesNot yet recruitingNCT07512024Not applicable
- Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic CholecystectomyNot yet recruitingNCT07865455Phase 4
- STALL vs Sole Local Wound Infiltration in Laparoscopic CholecystectomyRecruitingNCT06123117Not applicable1 country
- Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under SedationNot yet recruitingNCT07637721Not applicable1 country
- ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in ElderlyRecruitingNCT07001423Not applicable1 country
- Improvised Endobag vs Direct Gallbladder Extraction in Laparoscopic CholecystectomyRecruitingNCT07823803Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of CnU Capsule 750 mg in Patients With Cholesterol Gallstones(GB Stones).RecruitingNCT07005752Phase 41 country
- ABCG8, UGT1A1 and Gallstone Disease After Bariatric SurgeryNot yet recruitingNCT07702630
- Rectointercostal Plane Block (RICPB) for Laparoscopic CholecystectomyNot yet recruitingNCT07676552Not applicable1 country
- Comparison of Gallbladder Extraction Via Subxiphoid vs Infraumbilical Port in Laparoscopic CholecystectomyRecruitingNCT07672145Not applicable1 country
- EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON StudyNot yet recruitingNCT07655778Not applicable
- ESP vs Subcostal TAP Block for Analgesia After Laparoscopic CholecystectomyNot yet recruitingNCT07661693Not applicable1 country
- Endoscopic vs Non-endoscopic Drainage for Benign Gallbladder Diseases in High-risk Patients or Patients Desiring Gallbladder PreservationNot yet recruitingNCT076498111 country
- Transabdominal and Laparoscopic Ultrasound in a Bariatric SettingRecruitingNCT07453186Not applicable1 country
- Treatment Outcomes and Complications of Three Therapeutic Approaches for Concomitant Choledocholithiasis and CholecystolithiasisRecruitingNCT074130681 country
- Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant CholedocholithiasisRecruitingNCT07495111Not applicable1 country
- Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask AirwayRecruitingNCT03812718Not applicable1 country
- Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic InterventionsRecruitingNCT056892551 country
- Effect of Erector Spinae Plane Block on Postoperative Respiratory Function After Laparoscopic CholecystectomyNot yet recruitingNCT07478601Not applicable1 country
- Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating RoomRecruitingNCT074736871 country
- Impact of Pringle Maneuver on Postoperative Gallbladder Diseases After HepatectomyRecruitingNCT074528481 country
- Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.RecruitingNCT07421011Phase 11 country
- EULAT Eradicate GBCRecruitingNCT061927195 countries
- Pain Diary Use After Laparoscopic CholecystectomyRecruitingNCT07308730Not applicable1 country
- TENS for Anxiety, Pain, and Satisfaction After Laparoscopic CholecystectomyRecruitingNCT07307703Not applicable1 country
- Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric IschemiaRecruitingNCT064687741 country
- Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical StudyRecruitingNCT07051980Phase 21 country
- COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for PatientsRecruitingNCT07012772Phase 21 country
- Comparison of Three Ports and Four Ports Laparoscopic CholecystectomyNot yet recruitingNCT06873594Not applicable
- Prevention of NAFLD and CVD Through Lifestyle InterventionRecruitingNCT05618626Not applicable1 country
- A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone DiseaseRecruitingNCT06405906Not applicable1 country
- Cholecystectomy vs EUS-guided GBD With Stone RemovalRecruitingNCT06038201Not applicable1 country
- Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of ComplicationsRecruitingNCT06311305Not applicable1 country
- Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic CholecystectomyRecruitingNCT05775133Not applicable1 country
- Gallbladder Infundibulum as a Guide for Ductal Identification.RecruitingNCT062392331 country
- Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy CasesRecruitingNCT060364981 country
- Incidence of Cholelithiasis After Bariatric Surgery in Sohag University HospitalEnrolling by invitationNCT058036681 country
- A Randomized Controlled Trial Comparing the Effects of Different Anesthetic Sedatives on PONV in Laparoscopic CholecystectomyCompletedNCT07758803Phase 41 country
- Comparison of Postoperative Pain, Nausea, and Vomiting Between Veress Needle and Direct Trocar Entry in Laparoscopic CholecystectomyCompletedNCT07924254Not applicable1 country
- Hasson Versus Veress Access With Umbilical Versus Epigastric Gallbladder Extraction in Laparoscopic CholecystectomyCompletedNCT07887139Not applicable1 country
- USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic CholecystectomyCompletedNCT07552701Not applicable1 country
- Optimal Timings of Laparoscopic Cholecystectomy After ERCP in Patients With Gallstones Along With CBD StonesCompletedNCT07517627Not applicable1 country
- Using da Vinci SP System for Patients With Cholelithiasis and CholedocholithiasisCompletedNCT06852937Not applicable1 country
- Multicenter Cohort of 768 High-risk Patients With Symptomatic Gallstones, Adding Cholecystectomy Did Not Increase Length of Stay or Perioperative Morbidity, Supporting it as a Safe Single-stage OptionCompletedNCT07772440
- Validation of Serum Metabolite Differences in Patients With Gallstones and Gallbladder CancerCompletedNCT077444774 countries