Choledocholithiasis clinical trials
The registry lists 109 studies for Choledocholithiasis across more than 10 countries. 24 are recruiting or about to start. 75 of them are mainly about Choledocholithiasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Who runs them
Asian Institute of Gastroenterology, India (5) · National Taiwan University Hospital (4) · Beijing Friendship Hospital (3) · First People's Hospital of Hangzhou (3) · Stanford University (3) · University of Southern California (3) · National Liver Institute, Egypt (3) · National University of Malaysia (2)
What is being tested here
Drugs under test in Choledocholithiasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Nov 2026Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected Choledocholithiasis · Asian Institute of Gastroenterology, India
- Dec 2026Efficacy of Fistulotomy for Biliary Cannulation · Coordinación de Investigación en Salud, Mexico
- Dec 2026Percutaneous Cholangiopancreatoscopy Registry · Johns Hopkins University
- Dec 2026Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis · Peking University Third Hospital
- Jan 2027Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for Choledocholithiasis · Riga East Clinical University Hospital
- Feb 2027Pre-cut Versus Intentional Double Guidewire for ERCP Cannulation: Prospective, Randomized Controlled Trial · Asian Institute of Gastroenterology, India
- Oct 2027The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis. · Riga East Clinical University Hospital
Who these studies take
Of the 18 Choledocholithiasis studies recruiting now, 10 (56%) set no upper age limit and 1 (6%) stop at 75 or younger. 4 (22%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (22%) | 4 (22%) |
| 18 | 15 (83%) | 15 (83%) |
| 30 | 16 (89%) | 16 (89%) |
| 40 | 16 (89%) | 16 (89%) |
| 50 | 16 (89%) | 16 (89%) |
| 65 | 16 (89%) | 16 (89%) |
| 75 | 18 (100%) | 18 (100%) |
| 85 | 14 (78%) | 14 (78%) |
Across all 109 studies, recruiting or not: 13% stop at 75 or younger and 3% at 65; 16% take children; 0% are for women only and 0% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Choledocholithiasis studies take
Of 43 interventional studies with no phase under Choledocholithiasis, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo12–36 · 43 studies | — | 21 mo12–36 · 41 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 109. Browse all 109 → or search them.
- ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in ElderlyRecruitingNCT07001423Not applicable1 country
- Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for CholedocholithiasisRecruitingNCT07814976Not applicable1 country
- EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON StudyNot yet recruitingNCT07655778Not applicable
- Optimizing the Evaluation and Management of Patients With Suspected CholedocholithiasisRecruitingNCT051419161 country
- Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct StonesRecruitingNCT07418112Phase 41 country
- Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute CholangitisRecruitingNCT07407491Phase 21 country
- Pre-cut Versus Intentional Double Guidewire for ERCP Cannulation: Prospective, Randomized Controlled TrialNot yet recruitingNCT07329803Not applicable
- Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected CholedocholithiasisRecruitingNCT072831851 country
- Application of Machine Learning Models to Reduce Need for Diagnostic EUS or MRCP in Patients With Intermediate Likelihood of CholedocholithiasisRecruitingNCT060663721 country
- Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp.RecruitingNCT07130864Not applicable1 country
- Spanish Registry of Direct Cholangiopancreatoscopy by Single OperatorNot yet recruitingNCT07064447
- Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct StonesRecruitingNCT07008170Not applicable1 country
- Efficacy of Fistulotomy for Biliary CannulationRecruitingNCT04037007Not applicable1 country
- Clinical Trial Comparing ERCP vs ERCP and Transmural Gall Bladder DrainageRecruitingNCT03921502Not applicable1 country
- Spanish Registry of Quality Indicators and Adverse Events of Endoscopic Retrograde CholangiopancreatographyNot yet recruitingNCT06670547
- Dutch Cholecystitis Snapshot StudyRecruitingNCT063498631 country
- The Treatment Effect for Asymptomatic Common Bile Duct StoneRecruitingNCT062150401 country
- Microbiological Assessment of Bile in Patients Undergone to Endoscopic Retrograde Cholangiography (ERCP): the "Microbile Registry"RecruitingNCT061155641 country
- Role of Prophylactic Biliary Stent in Reducing the Recurrence of CholedocholithiasisNot yet recruitingNCT06060002Not applicable
- Recurrent Extrahepatic Bile Duct Stones as a Late Complication of ERCP in Patients With Coexisting Intra- and Extrahepatic Bile Duct StonesRecruitingNCT060411131 country
- RCT on Robotic vs. Endo-laparoscopic Approach for Difficult CholedocholithiasisRecruitingNCT05611840Not applicable1 country
- Modified Laparoscopic Transcystic Biliary Drainage in the Management of CholecystocholedocholithiasisNot yet recruitingNCT06011941Not applicable1 country
- EPLBD With Limited EST vs. EPLBD for CholedocholithiasisRecruitingNCT05056506Not applicable1 country
- Los Angeles Prospective GI Biliary and EUS SeriesRecruitingNCT021969351 country
- Detection of Residual Bile Duct Stones by Cholangioscopy After Negative ERCP Cholangiography and Interobserver Agreement: A Self-Controlled StudyCompletedNCT07906782Not applicable1 country
- Using da Vinci SP System for Patients With Cholelithiasis and CholedocholithiasisCompletedNCT06852937Not applicable1 country
- Common Bile Duct Pressure After Surgical ExplorationCompletedNCT04968873Not applicable
- Antimicrobial Resistance in Acute CholangitisCompletedNCT061979841 country
- IDUS in CBD Stone Recurrence High Risk PatientsCompletedNCT06265311Not applicable1 country
- The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis.Active, not recruitingNCT07503964Not applicable1 country
- Role of Prophylactic Aggressive Hydration to Prevent Post-ERCP PancreatitisCompletedNCT07417020Not applicable1 country
- Percutaneous Cholangiopancreatoscopy RegistryActive, not recruitingNCT052103221 country
- Double Stent for Biliary Stones in Cirrhotic PatientsCompletedNCT07337291Not applicable1 country
- CBD Stenting vs Non-Stenting for CholedocholithiasisCompletedNCT07331142Not applicable1 country
- Endoscopic Antegrade Sphincterotomy (ASD) Versus Standard SphincterotomyCompletedNCT04406961Not applicable1 country
- Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable DuodenoscopeCompletedNCT05429203Not applicable1 country
- Effectiveness and Safety of Single-session Endoscopic Stone ExtractionCompletedNCT06349954Not applicable1 country
- Immediate vs. Elective Endoscopic Removal of Large CBD Stones in High-Risk Elderly PatientsCompletedNCT06948279Not applicable1 country
- Ketamine-midazolam as a Sedative Agent in Endoscopic Retrograde Cholangiopancreatography.CompletedNCT06111872Phase 21 country
- Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).CompletedNCT01414400Not applicable1 country
- One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in CholecystocholedocholithiasisCompletedNCT066762411 country
- Intraoperative ERCP Versus Therapeutic Splitting in Cholecysto-, CholedocholithiasisCompletedNCT061301631 country
- ERCP and LC for Cholecystocholedocholithiasis in Children: Should It Be Accomplished in One or Repeated Hospitalization?CompletedNCT066729911 country
- Non-Complex Biliary Stones DSC vs ERCCompletedNCT03421340Not applicable4 countries
- Evaluation of Choledochoduodonostomy vs Hepaticojejunostomy in Paients With Choledocholithiasis Indicated for Shunt.Status unknownNCT06601387Not applicable1 country
- Enhanced Recovery After Surgery Program Versus Conventional Care for Laparoscopic Common Bile Duct ExplorationCompletedNCT06630767Not applicable1 country
- For Patients with Stones in Gallbladder and Bile Duct Stones At the Same Time, Surgical Removal of the Gallbladder with the Laparoscope is Done in the Same Admission Compared to Its Removal After 6 Weeks Following Successful Removel of the Stones from the Bile Ducts by the Side View EndoscopeCompletedNCT06599437Not applicable1 country
- Efficacy and Safety of Single-session Endoscopic Stone ExtractionCompletedNCT063271261 country
- Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?CompletedNCT063405941 country
- Comparison of LCBDE vs ERCP + LC for CholedocholithiasisCompletedNCT02515474Not applicable1 country