Gallstones clinical trials
The registry lists 199 studies for Gallstones across more than 10 countries. 35 are recruiting or about to start. 131 of them are mainly about Gallstones (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Who runs them
Hepatopancreatobiliary Surgery Institute of Gansu Province (7) · Mansoura University (5) · Karolinska Institutet (5) · Chinese University of Hong Kong (5) · Minia University (4) · Assiut University (4) · Services Hospital, Lahore (3) · Air Force Military Medical University, China (3)
What is being tested here
Drugs under test in Gallstones studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ursodeoxycholic Acid | 1 | 2 | 5 |
| Bupivacaine | 1 | 0 | 4 |
| Bifidobacterium spp. | 1 | 0 | 1 |
| Dexamethasone | 0 | 0 | 1 |
| Obeticholic acid | 0 | 0 | 1 |
| Levobupivacaine | 0 | 0 | 1 |
| Aramchol | 0 | 0 | 1 |
| DA-9701 | 0 | 0 | 1 |
| Mosapride | 0 | 0 | 1 |
| Ursodoxicoltaurine | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jul 2027Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis · Phase 3 · Hospital General Universitario de Alicante
- Dec 2026Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones · Mahidol University
- Dec 2026Diagnosis and Percutaneous Treatment of Biliary Tract Diseases · IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Dec 2026Efficacy and Safety of a Novel ERCP Robot in the Treatment of Common Bile Duct Stone · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- Dec 2026A Strategy for Gallstone Expulsion Through Dietary Therapy · Hepatopancreatobiliary Surgery Institute of Gansu Province
- Dec 2026Modified Laparoscopic Transcystic Biliary Drainage in the Management of Cholecystocholedocholithiasis · Peking University Third Hospital
- Jan 2027A Study on the Efficacy and Safety of Endoscopic Ultrasound-guided Gastro-/Duodeno-cholecystostomy for the Treatment of Gallstones. · Tongji Hospital
- Apr 2027The Pro-Chol Study · Nordsjaellands Hospital
- Apr 2027Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery · Chinese University of Hong Kong
- Apr 2027Informing Patients About Their Surgery's Environmental Impact: an Effective Pathway to Sustainable Healthcare? · University of Amsterdam
Who these studies take
Of the 24 Gallstones studies recruiting now, 11 (46%) set no upper age limit and 10 (42%) stop at 75 or younger. 1 (4%) take children under 18. 2 (8%) are for women only and 0 (0%) for men only; 2 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 23 (96%) | 21 (88%) |
| 30 | 24 (100%) | 22 (92%) |
| 40 | 24 (100%) | 22 (92%) |
| 50 | 24 (100%) | 22 (92%) |
| 65 | 22 (92%) | 21 (88%) |
| 75 | 16 (67%) | 16 (67%) |
| 85 | 13 (54%) | 13 (54%) |
Across all 199 studies, recruiting or not: 31% stop at 75 or younger and 14% at 65; 16% take children; 5% are for women only and 1% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Gallstones studies take
Of 58 interventional studies with no phase under Gallstones, half reached primary completion within 20 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 20 mo12–43 · 58 studies | — | 20 mo12–43 · 58 studies |
| Observational | 34 mo9–61 · 23 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 199. Browse all 199 → or search them.
- Surgical Techniques: Robotic Versus Conventional Laparoscopic Cholecystectomy IN Benign Gallbladder DiseaseRecruitingNCT07119203Not applicable1 country
- Influence of Gut Microbiome in Gallstone DiseaseRecruitingNCT057324801 country
- ChOlanGiography Performed Routinely Versus Selectively During Cholecystectomy: A NAtional Registry-based Randomized Controlled TrialRecruitingNCT07002619Not applicable1 country
- Ultrasound for Postop Lung Issues in Low-Flow AnesthesiaRecruitingNCT068245061 country
- A Study on the Efficacy and Safety of Endoscopic Ultrasound-guided Gastro-/Duodeno-cholecystostomy for the Treatment of Gallstones.Enrolling by invitationNCT07522385Not applicable1 country
- Informing Patients About Their Surgery's Environmental Impact: an Effective Pathway to Sustainable Healthcare?Not yet recruitingNCT07505238Not applicable1 country
- TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk PatientsRecruitingNCT07480785Not applicable1 country
- A Strategy for Gallstone Expulsion Through Dietary TherapyRecruitingNCT06699030Not applicable1 country
- The Pro-Chol StudyRecruitingNCT072451081 country
- Laser vs Electrohydraulic Lithotripsy for Difficult CBD StonesRecruitingNCT07030829Not applicable1 country
- Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct StonesRecruitingNCT07008170Not applicable1 country
- Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic SurgeryRecruitingNCT06926374Not applicable1 country
- Indocyanine Green Fluorescence During Fundus First Laparoscopic CholecystectomyNot yet recruitingNCT06918210Not applicable
- Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute PancreatitisRecruitingNCT04924868Phase 31 country
- Diagnosis and Percutaneous Treatment of Biliary Tract DiseasesRecruitingNCT06816615Not applicable1 country
- Genetic Variants Associated With the Risk of Gall Stones and Cirrhosis.Not yet recruitingNCT066797381 country
- EOIB for Laparoscopic CholecystectomyRecruitingNCT06656299Not applicable1 country
- Dutch Cholecystitis Snapshot StudyRecruitingNCT063498631 country
- ALgerian Cholecystectomy Outcomes and Determinants Study (AL-CODS)Not yet recruitingNCT06481007
- A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone DiseaseRecruitingNCT06405906Not applicable1 country
- Prediction Model for Early Biliary Stasis After Bariatric SurgeryNot yet recruitingNCT06385860
- Cholecystectomy vs EUS-guided GBD With Stone RemovalRecruitingNCT06038201Not applicable1 country
- Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of ComplicationsRecruitingNCT06311305Not applicable1 country
- Probiotics for Gallstones in Post-bariatric Surgery PatientsRecruitingNCT06287931Not applicable1 country
- Failed Retrograde Cholangiopancreatography (ERCP) Stone Extraction: Surgical InterferenceNot yet recruitingNCT05746832Not applicable1 country
- ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORERecruitingNCT062279881 country
- Endoscopic Common Bile Duct Stones Clearance During PregnancyRecruitingNCT060929051 country
- Application and Translational Research of 3D Printed in Treatment of Choledocholithiasis Under ERCPNot yet recruitingNCT06071247Not applicable
- Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy CasesRecruitingNCT060364981 country
- Modified Laparoscopic Transcystic Biliary Drainage in the Management of CholecystocholedocholithiasisNot yet recruitingNCT06011941Not applicable1 country
- preGallstep - A Clinical Pilot TrialRecruitingNCT04801238Not applicable1 country
- The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Benign and Malignant Biliary Tract DiseasesNot yet recruitingNCT05896956
- Effect of Abdominal Massage on Prevention of Recurrent Common Bile Duct Stones After Endoscopic SphincterotomyRecruitingNCT05892458Not applicable1 country
- Early Versus Late Laparoscopic Exploration of Common Bile Duct After Failure of Extraction of Common Bile Duct Stones by ERCPNot yet recruitingNCT05823181
- Post-Cholecystectomy Quality of LifeRecruitingNCT033261541 country
- Comparison of the Efficacy of Different Analgesic Strategies for Pain Control After Laparoscopic Cholecystectomy (LC)Active, not recruitingNCT07897435Not applicable1 country
- RELIEF-pathway in Patients With Upper Abdominal PainActive, not recruitingNCT06002516Not applicable1 country
- AI-Assisted Cholecystectomy StudyActive, not recruitingNCT07705828Not applicable1 country
- Impact of COVID-19 Pandemic on Single-stage Laparoscopic Cholecystectomy and Laparoscopic Common Bile Duct Exploration ServiceCompletedNCT06974045
- EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.CompletedNCT04197908Not applicable1 country
- Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic ScalpelCompletedNCT07473388Not applicable1 country
- Efficacy and Safety of a Novel ERCP Robot in the Treatment of Common Bile Duct StoneActive, not recruitingNCT07368335Not applicable1 country
- Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube DrainageCompletedNCT073456631 country
- GallRiks ERC Anesthesia StudyCompletedNCT07205380
- Effect of TENS on Patient Outcomes After Laparoscopic CholecystectomyCompletedNCT05962853Not applicable1 country
- Vegetarian Diet and Chronic Degenerative DiseasesCompletedNCT034705841 country
- Early Versus Delayed Laparoscopic Cholecystectomy for Acute CholecystitisCompletedNCT07101315Not applicable1 country
- Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic CholecystectomyCompletedNCT07098429Phase 41 country
- Safety and Feasibility of Early T-tube Cholangiography Performed Within 2 to 3 Days After Laparoscopic Common Bile Duct ExplorationCompletedNCT07058740Not applicable1 country
- Synergistic Effects of Natural Oils and Herbal Extracts on Cholesterol Gallstone Dissolution: In Vitro Comparison With Rowachol®CompletedNCT06972134Not applicable1 country