Drug
Ursodeoxycholic Acid clinical trials
Also written Ursodiol and Urso.
- studies test it
- 96
- open now
- 17
- in phase 3
- 20
- first study started
- 1994
Keep track of what changes. Save the Ursodeoxycholic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Other names
Studies by the year they started
96 studies that test it; most in 2026 (9)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1995 | 1 |
| 1998 | 1 |
| 2001 | 1 |
| 2002 | 3 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 4 |
| 2008 | 4 |
| 2009 | 4 |
| 2010 | 4 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 3 |
| 2014 | 5 |
| 2015 | 3 |
| 2016 | 6 |
| 2017 | 4 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 4 |
| 2021 | 8 |
| 2022 | 3 |
| 2023 | 6 |
| 2024 | 5 |
| 2025 | 2 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 17
- Phase 2
- 30
- Phase 3
- 20
- Phase 4
- 21
- No phase
- 18
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 81
Daewoong Pharmaceutical Co. LTD. (7) · Tanta University (4) · Institute of Liver and Biliary Sciences, India (2) · Teva Pharmaceuticals USA (2) · Radboud University Medical Center (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Dr. Falk Pharma GmbH (2) · Jinling Hospital, China (2)
Often tested with
Tested in the same studies.
Pentoxifylline (3) · Thiamine (2) · Sitagliptin (2) · Omega-3 fatty acid (1) · Phototherapy (1) · Zinc Sulfate (1) · Nirmatrelvir and ritonavir drug combination (1) · Bevacizumab (1)
Studies
Open first, then newest update. How each study uses Ursodeoxycholic Acid is read from its arms, and is right about nine times in ten.
Testing it · 96
- Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal TumorsRecruitingPhase 2Jinling Hospital, ChinaNCT07672860Written as UDCA (Ursodeoxycholic acid)
- Effect of Adjunctive Ursodeoxycholic Acid on Oxidative Stress, Inflammation, and Organ Dysfunction in Adults With SepsisNot yet recruitingPhase 2/3Tanta UniversityNCT07852780Written as Ursodeoxycholic Acid
- Comparing UDCA and Corticosteroids in Immunotherapy Induced Cholestatic HepatitisRecruitingPhase 2University Hospital, MontpellierNCT07378761Written as UDCA (Ursodeoxycholic acid)
- Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder CancerRecruitingPhase 2Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT07717242Written as Ursodeoxycholic Acid
- Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose ToleranceRecruitingNot applicableFirst Affiliated Hospital Xi'an Jiaotong UniversityNCT06684106Written as Ursodeoxycholic acid (UDCA) 500 mg
- Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration in Adult Living Donor Liver Transplant (LDLT) Recipients.Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT07664020Written as Ursodeoxycholic acid
- Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard TherapyNot yet recruitingEarly Phase 1Medical College of WisconsinNCT06884748Written as Ursodiol 500 MG
- The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect HyperbilirubinemiaRecruitingNot applicableTishreen University HospitalNCT07110987Written as ursodeoxycholic acid (UDCA)
- Comparative Evaluation of Oral Ursodeoxycholic Acid in Reducing Bilirubin Levels Among Patients With Acute Viral HepatitisNot yet recruitingNot applicableCombined Military Hospital, PakistanNCT07525401Written as Ursodeoxycholic Acid
- UDCA to Prevent Post-TIPS Hepatic EncephalopathyNot yet recruitingNot applicableWest China HospitalNCT07273734Written as Ursodeoxycholic Acid (UDCA)
- Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal MetaplasiaRecruitingPhase 4Yongquan ShiNCT06610760Written as Ursodeoxycholic Acid
- Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment SurgeryRecruitingPhase 3Hopital FochNCT06294847Written as Ursolvan
- Clinical Research of Tapering UDCA in PBC Patients With a Complete ResponseRecruitingPhase 4Peking Union Medical College HospitalNCT04650243Written as ursodeoxycholic acid
- Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute PancreatitisRecruitingPhase 3Hospital General Universitario de AlicanteNCT04924868Written as Ursodeoxycholic Acid
- PD-L1 Inhibitor + RT ± Ursodeoxycholic Acid in Recurrent/Metastatic HER2-Neg Breast CancerNot yet recruitingPhase 2Cancer Institute and Hospital, Chinese Academy of Medical SciencesNCT06842472Written as Ursodeoxycholic Acid (URSO)
- Ursodeoxycholic Acid as add-on Therapy in Type 2 Diabetes MellitusRecruitingPhase 2/3Tanta UniversityNCT05902468Written as Ursodeoxycholic acid
- A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-InfectionNot yet recruitingPhase 2National Taiwan University HospitalNCT05467553Written as Ursodeoxycholic acid
- Effect of Ursodeoxycholic Acid on Indirect Hyperbilirubinemia in Neonates Treated With PhototherapyCompletedNot applicableMuhammad Aamir LatifNCT07867366Written as Phototherapy with ursodeoxycholic acid
- Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal HyperbilirubinemiaCompletedPhase 4Amira Adel FoulyNCT06517862Written as Ursodeoxycholic acid
- Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac SurgeryCompletedPhase 4China National Center for Cardiovascular DiseasesNCT05690646Written as Ursodeoxycholic acid
See all 96 studies that test Ursodeoxycholic Acid →
Given in every arm · 22 — Ursodeoxycholic Acid is usual care beside what is tested
- Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary CholangitisRecruitingPhase 2/3Xijing Hospital of Digestive DiseasesNCT05749822Written as UDCA
- Glucocorticoids for Acute Drug Induced Liver Injury With HyperbilirubinemiaRecruitingNot applicableGeneral Hospital of Shenyang Military RegionNCT06922669Written as Ursodeoxycholic acid capsules
- Fenofibrate in Patients With Primary Biliary Cholangitis (PBC)RecruitingPhase 2/3Xijing Hospital of Digestive DiseasesNCT06365424Written as UDCA
- Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related HepatitisRecruitingPhase 2Inge Marie SvaneNCT04810156Written as Ursodeoxycholic acid
- Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary CholangitisActive, not recruitingPhase 2/3Han YingNCT06174402Written as UDCA
- Obeticholic Acid Versus Placebo, in Combination with Ursodeoxycholic Acid in Patients with Primary Biliary CirrhosisCompletedPhase 3Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.NCT06715319Written as UDCA
- Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary CholangitisCompletedPhase 3Nanjing Chia-tai Tianqing PharmaceuticalNCT05450887Written as UDCA
- Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary CirrhosisCompletedPhase 3Xijing Hospital of Digestive DiseasesNCT02823353Written as UDCA
- Fenofibrate for Patients With Primary Biliary Cirrhosis Who Had An Inadequate Response to Ursodeoxycholic AcidStatus unknownPhase 3Xijing Hospital of Digestive DiseasesNCT02823366Written as UDCA
- Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCAWithdrawnPhase 1/2Beijing 302 HospitalNCT02965911Written as UDCA
- Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)Status unknownPhase 3Chia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT04956328Written as UDCA
- A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary CholangitisStatus unknownPhase 3Instituto Mexicano del Seguro SocialNCT04751188Written as Ursodeoxycholic Acid
- Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary CholangitisCompletedNot applicableNational Scientific Medical Center, KazakhstanNCT03665519Written as Ursodeoxycholic Acid
- Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary CirrhosisCompletedPhase 2Mirum Pharmaceuticals, Inc.NCT01904058Written as Ursodeoxycholic Acid
- Fibrates in Pediatric CholestasisCompletedPhase 2Hoda A. AttaNCT03586674Written as Ursogal
- Umbilical Cord Mesenchymal Stem Cells in Primary Sclerosing CholangitisStatus unknownPhase 1/2Fuzhou General HospitalNCT03516006Written as UDCA
- Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-respondersStatus unknownPhase 3Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranNCT02937012Written as Ursodeoxycholic Acid
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of PruritusCompletedPhase 2GlaxoSmithKlineNCT01899703Written as Ursodeoxycholic acid
- Autologous Bone Marrow Stem Cells Infusion for the Treatment of Liver Diseases.Status unknownPhase 2Wenzhou Medical UniversityNCT02943707Written as drugs such as Ursodeoxycholic Acid tablets
- Fuzhenghuayu for Patients With PBC Who Had An Inadequate Response to Ursodeoxycholic AcidStatus unknownPhase 3Xijing Hospital of Digestive DiseasesNCT02916641Written as UDCA
Showing 20 of 22.
As the comparator · 14 — what is tested is compared with Ursodeoxycholic Acid
- FIREFLY Trial: Fenofibrate Intervention---Randomized Evaluation in First-Line PBC TherapyRecruitingPhase 3Xijing Hospital of Digestive DiseasesNCT07296458Written as UDCA (Ursodeoxycholic acid)
- A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis CharacteristicsEnrolling by invitationPhase 2/3Han YingNCT06591468Written as UDCA (Ursodeoxycholic acid)
- Gepaktiv vs UDCA and Ademetionine in MAFLD With HepatomegalyRecruitingNot applicablePhenomen PharmaNCT07068191Written as UDCA (Ursodeoxycholic acid)
- A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)WithdrawnPhase 2HighTide Therapeutics (Hong Kong) LimitedNCT03678480Written as Ursodeoxycholic Acid
- A Pilot Study of Fenofibrate and Ursodeoxycholic Acid in the Treatment of Newly Diagnosed Primary Biliary CholangitisCompletedEarly Phase 1Han YingNCT06591455Written as UDCA (Ursodeoxycholic acid)
- Study to Compare the Efficacy & Safety of Ursoplus Capsules vs. UDCA vs. Placebo Among Chronic Liver Disease PatientsStatus unknownPhase 4MinaPharm PharmaceuticalsNCT05849558Written as UDCA 250mg
- Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap SyndromeStatus unknownNot applicableXiaoli FanNCT02936596Written as Ursodeoxycholic Acid
- Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features IIStatus unknownPhase 4West China HospitalNCT04617561Written as Ursodeoxycholic acid
- Therapeutic And Dietary Effects Of The Sublimated Mare's Milk Supplement In Patients With Non-Alcoholic SteatohepatitisCompletedNot applicableMedical Centre Hospital of the President's Affairs Administration, Republic of KazakhstanNCT03664596Written as Ursodeoxycholic Acid
- Probiotics for Gallstones in Post-bariatric Surgery Patients：A Prospective Randomized TrialStatus unknownNot applicableMin-Sheng General HospitalNCT03247101Written as Urso group
- Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in InfantsWithdrawnPhase 2The University of Texas Health Science Center at San AntonioNCT02420496Written as Ursodeoxycholic Acid
- Efficacy and Safety Study of TUDCA Compare UDCA to Treatment Chronic Cholestatic Liver Disease-PBCCompletedPhase 3Beijing Trendful Kangjian Medical Information Consulting Limited CompanyNCT01829698Written as ursodeoxycholic acid
- Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary CirrhosisCompletedPhase 3Beijing Friendship HospitalNCT01857284Written as Ursodeoxycholic Acid Capsules
- Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary CirrhosisStatus unknownPhase 1Robert Chunhua Zhao, MD, PhDNCT01440309Written as ursodeoxycholic acid
Codes
What other systems call Ursodeoxycholic Acid · ClinicalTrials.gg INT008389
- MeSH (NLM) D014580Ursodeoxycholic AcidConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 724L30Y2QRURSODIOLConfirmed FDA, NLM
- RxNorm 11065One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014580 | Ursodeoxycholic Acid | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 724L30Y2QR | URSODIOL | Confirmed FDA, NLM |
| RxNorm | 11065 | — | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.