Cardiovascular Diseases clinical trials
The registry lists 5,368 studies for Cardiovascular Diseases across more than 10 countries. 939 are recruiting or about to start. 2,070 of them are mainly about Cardiovascular Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 251 narrower conditions too, such as Stroke: 69,176 studies, 14,990 open.
ClinicalTrials.gov finds 67,266 studies for Cardiovascular Diseases. How that becomes 5,367 here
This page counts the studies the registry files under Cardiovascular Diseases, and those it files under no condition that list Cardiovascular Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 67,266Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −59,033Filed under a narrower condition, counted on its own pageStroke 7,577 · Heart Failure 5,221 · Hypertension 5,016 · Coronary Artery Disease 4,199 · Multiple Myeloma 3,659 · Atrial Fibrillation 3,145 · 231 more
- −92List Cardiovascular Diseases as a condition, but the registry did not file them under itMost often written as “Cardiovascular Disease Risk Factors” (7), “Cardiovascular Disease Risk Factor” (7), and “Cardiovascular Disease Risk” (6). The registry filed 42 of them under no condition at all, and the others under other conditions only, most often Obesity (11) and Motor Activity (9).
- −2,774Match it another way318 name it in the title, 53 in a keyword, and 2,403 by a synonym or other text the search reads.
- 5,367The count on this page
Get an email when these change. Save the Cardiovascular Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (493) · Brigham and Women's Hospital (45) · VA Office of Research and Development (44) · Duke University (42) · AstraZeneca (39) · University of Toronto (39) · Penn State University (37) · University of Pennsylvania (36)
What is being tested here
Drugs under test in Cardiovascular Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 7 | 7 | 40 |
| Rivaroxaban | 7 | 2 | 12 |
| Semaglutide | 6 | 1 | 7 |
| Colchicine | 5 | 3 | 11 |
| Omega-3 fatty acid | 3 | 6 | 17 |
| Metformin | 3 | 1 | 15 |
| Empagliflozin | 3 | 0 | 8 |
| Inclisiran | 3 | 4 | 6 |
| Atorvastatin | 2 | 4 | 36 |
| Fish Oils | 2 | 1 | 11 |
Drug classes tested here SGLT2 inhibitors 9 open · NSAIDs 7 open · Factor Xa inhibitors 7 open · Statins 6 open · GLP-1 receptor agonists 6 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs · Phase 3 · Penn State University
- Dec 2026Colchicine and Inflammation in Aortic Stenosis · Phase 3 · Radboud University Medical Center
- Dec 2026A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension · Phase 3 · United Therapeutics
- Dec 2026CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes · Phase 3 · VA Office of Research and Development
- Jan 2027PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis · Phase 3 · University of Alabama at Birmingham
- Jan 2027A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event · Phase 3 · AstraZeneca
- Sep 2027REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels · Phase 3 · Novo Nordisk A/S
- Nov 2026The Cooking for Health Optimization and Disease Prevention (CHOP) Trial · Tulane University
- Nov 2026Zenith® Fenestrated+ Clinical Study · Cook Research Incorporated
- Nov 2026Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS) · Medtronic Cardiac Ablation Solutions
Who these studies take
Of the 666 Cardiovascular Diseases studies recruiting now, 389 (58%) set no upper age limit and 141 (21%) stop at 75 or younger. 76 (11%) take children under 18. 33 (5%) are for women only and 7 (1%) for men only; 174 (26%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 66 (10%) | 65 (10%) |
| 18 | 462 (69%) | 449 (67%) |
| 30 | 525 (79%) | 507 (76%) |
| 40 | 582 (87%) | 559 (84%) |
| 50 | 607 (91%) | 588 (88%) |
| 65 | 607 (91%) | 590 (89%) |
| 75 | 553 (83%) | 542 (81%) |
| 85 | 470 (71%) | 461 (69%) |
Across all 5,368 studies, recruiting or not: 30% stop at 75 or younger and 17% at 65; 18% take children; 6% are for women only and 9% for men only; 29% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cardiovascular Diseases studies take
Of 113 phase 4 interventional studies under Cardiovascular Diseases, half reached primary completion within 46 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 15 mo3–45 · 96 studies | 3 mo1–15 · 53 studies | 45 mo17–67 · 43 studies |
| Phase 1/2 | 40 mo34–62 · 20 studies | — | — |
| Phase 2 | 28 mo16–59 · 84 studies | — | 38 mo23–62 · 60 studies |
| Phase 3 | 57 mo34–83 · 82 studies | 48 mo29–79 · 42 studies | 57 mo41–95 · 40 studies |
| Phase 4 | 46 mo26–64 · 113 studies | — | 46 mo28–76 · 107 studies |
| Interventional, no phase | 26 mo12–49 · 1,216 studies | 26 mo15–53 · 139 studies | 26 mo12–48 · 1,077 studies |
| Observational | 61 mo24–192 · 664 studies | 31 mo15–48 · 84 studies | 70 mo28–196 · 580 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting11
- A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular DiseaseNov 10, 2026NCT07839936
- NightWare and Cardiovascular Health in Women With PTSDNov 6, 2026NCT07021014
- Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 DiabetesNov 5, 2026NCT07479329
- Tricuspid Regurgitation Treatment With LAPLACE Transcatheter Tricuspid Valve Replacement SystemNov 2, 2026NCT07687485
- Vasopressor Agents in Pulmonary Hypertension CrisisOct 30, 2026NCT07667829
Show 6 moreShow fewer
- Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk FactorsOct 22, 2026NCT06796582
- TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)Oct 21, 2026NCT07684313
- Hyperlipoproteinemia A as a Marker of Cardiovascular Risk in Patients With Stage 4 Chronic Kidney DiseaseOct 20, 2026NCT07141628
- Optimised Cardiovascular and Renal Protection in Patients With Chronic Kidney Disease and Cardiovascular DiseaseOct 15, 2026NCT07835828
- INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac RecoveryOct 13, 2026NCT06965504
- Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)Oct 13, 2026NCT07721649
Results posted3
- Decision Support for Adults Facing Implantable Cardioverter-Defibrillator Pulse Generator ReplacementNov 9, 2026NCT02668900
- Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in PSVTNov 6, 2026NCT07554170
- TRISCEND JAPAN StudyOct 27, 2026NCT05760989
Stopped1
- An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)TerminatedNov 10, 2026NCT05900141
Newly registered20
- High-Intensity Functional Training vs. Moderate-Intensity Continuous Training in Cardiovascular Disease PatientsNov 10, 2026NCT07929701
- A Clinical Study Testing Enicepatide in Participants Living With Overweight or Obesity and Cardiovascular DiseaseNov 5, 2026NCT07918846
- PET-MR Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Multisite)Nov 4, 2026NCT07916883
- Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)Nov 3, 2026NCT07912320
- Real-World Validation of A Minimally Disruptive Ambulatory Blood Pressure Monitoring (ABPM) Huawei Smartwatch in MalaysiaNov 3, 2026NCT07913607
Show 15 moreShow fewer
- Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac RehabilitationNov 2, 2026NCT07908810
- Cardiovascular Disease MultimorbidityNov 2, 2026NCT07909395
- Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation PatientsNov 2, 2026NCT07910812
- Relationship Between Insulin Dose and Complications in Type 1 DiabetesNov 2, 2026NCT07911033
- A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular RiskOct 28, 2026NCT07900633
- Wearable Ultrasound for Cardiac Monitoring During Surgery and in Intensive CareOct 23, 2026NCT07891052
- Reducing Arterial Inflammation Using Eplerenone and Statins in HIVOct 23, 2026NCT07892664
- Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity RisksOct 21, 2026NCT07884903
- EValuation of prognostIc and Cost reDuction by tElemonitoring iN CIEDs Usual carE: an Updated Analysis Using 2019-2023 DataOct 19, 2026NCT07881250
- Effects of a Specialized Diabetes and Heart Clinic and Detection of Unrecognized Heart Failure in People With Type 2 Diabetes and Cardiovascular DiseaseOct 16, 2026NCT07878325
- Effectiveness of the "Aktivplan" Digital Intervention for Supporting Regular Heart-Healthy Physical Activity Following Phase II Cardiac RehabilitationOct 16, 2026NCT07878520
- Digital Nudges to Improve Heart Health Actions After Community Screening in Malaysia (NADI-MyHeartRisk)Oct 16, 2026NCT07879144
- A Study on Abnormal Menstrual Bleeding in Chinese Women of Childbearing Age Taking Antithrombotic Drugs After Cardiovascular SurgeryOct 13, 2026NCT07870941
- A Study on the Impact of Recombinant Zoster Vaccine on Major Adverse Cardiovascular Events in Adults >=50 Years of Age With Established Cardiovascular Disease or With >=2 Cardiovascular Risk FactorsOct 13, 2026NCT07872046
- Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release TabletsOct 13, 2026NCT07872358
Studies
Recruiting first, then most recently updated. Showing 50 of 5,368. Browse all 5,368 → or search them.
- Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular GraftsRecruitingNCT04467671Phase 21 country
- A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular DiseaseRecruitingNCT07839936Phase 21 country
- High-Intensity Functional Training vs. Moderate-Intensity Continuous Training in Cardiovascular Disease PatientsNot yet recruitingNCT07929701Not applicable1 country
- VDyne TriNova Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)RecruitingNCT07516444Not applicable1 country
- A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart DiseaseRecruitingNCT07214376Not applicable2 countries
- Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIVRecruitingNCT06001814Not applicable1 country
- A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)RecruitingNCT07286578Not applicable4 countries
- Study to Determine the Clinical Significance of Intravascular OCT-NIRAFEnrolling by invitationNCT06374498Not applicable1 country
- Natural History Study of CADASILRecruitingNCT050724831 country
- Gut Microbiota in Metabolic SurgeryRecruitingNCT050009961 country
- NightWare and Cardiovascular Health in Women With PTSDRecruitingNCT07021014Not applicable1 country
- Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)RecruitingNCT07601425Phase 1/22 countries
- The CACHE Study: Coronary Artery Care in HaEmophiliaRecruitingNCT067062061 country
- Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19.RecruitingNCT066019981 country
- Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney TransplantationRecruitingNCT062344101 country
- Beta-Blocker Influences on Inflammatory and Neural Responses to StressRecruitingNCT06263452Phase 41 country
- Truway Diagnostic Tools in Primary CareEnrolling by invitationNCT07209527Early Phase 11 country
- The DANE-HEART Trial - Computed Tomography Coronary Angiography for Primary PreventionEnrolling by invitationNCT05677386Not applicable1 country
- Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart FailureRecruitingNCT06526195Not applicable8 countries
- A Clinical Study Testing Enicepatide in Participants Living With Overweight or Obesity and Cardiovascular DiseaseNot yet recruitingNCT07918846Phase 3
- Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 DiabetesRecruitingNCT074793291 country
- CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain SyndromesRecruitingNCT04709900Not applicable1 country
- A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High RiskRecruitingNCT07613294Phase 37 countries
- PET-MR Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Multisite)Not yet recruitingNCT079168831 country
- ELEVATE-HFpEF Clinical StudyRecruitingNCT06678841Not applicable15 countries
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular EventRecruitingNCT07783802Phase 24 countries
- Real-World Validation of A Minimally Disruptive Ambulatory Blood Pressure Monitoring (ABPM) Huawei Smartwatch in MalaysiaEnrolling by invitationNCT079136071 country
- A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular RiskNot yet recruitingNCT07900633Phase 321 countries
- Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)Enrolling by invitationNCT07912320Not applicable1 country
- A Study to Lower Blood Pressure One Year After Childbirth in Women Who Had PreeclampsiaNot yet recruitingNCT06798649Not applicable
- Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac RehabilitationNot yet recruitingNCT07908810Not applicable1 country
- Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation PatientsRecruitingNCT07910812Not applicable1 country
- Relationship Between Insulin Dose and Complications in Type 1 DiabetesNot yet recruitingNCT079110331 country
- Cardiovascular Disease MultimorbidityNot yet recruitingNCT07909395Not applicable2 countries
- Tricuspid Regurgitation Treatment With LAPLACE Transcatheter Tricuspid Valve Replacement SystemRecruitingNCT07687485Not applicable1 country
- Vasopressor Agents in Pulmonary Hypertension CrisisRecruitingNCT07667829Not applicable1 country
- Effect of Propionic Acid Supplementation on Endothelial FunctionNot yet recruitingNCT05135702Not applicable
- Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.RecruitingNCT03242642Not applicable3 countries
- Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)RecruitingNCT025439961 country
- Techquity by FAITH!Enrolling by invitationNCT06187077Not applicable1 country
- Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia RegistryRecruitingNCT072562492 countries
- Diabetes and Heart Disease Risk in BlacksRecruitingNCT000018531 country
- Targeted Health Dialogues in Primary CareRecruitingNCT049127391 country
- Hemodynamics After Resistance TrainingRecruitingNCT07022340Not applicable1 country
- The TRICURE EFS StudyRecruitingNCT06506942Not applicable2 countries
- Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular InterventionRecruitingNCT06909565Phase 41 country
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular DiseaseRecruitingNCT07064473Phase 351 countries
- Healthy Living BEYOND Weight StudyRecruitingNCT070753411 country
- Multi-organ Imaging of Microvascular and Metabolic FunctionNot yet recruitingNCT07604207Early Phase 1
- ALDH2 Genetic Testing in East Asian CommunityNot yet recruitingNCT07392775Not applicable1 country