Multiple Myeloma clinical trials
The registry lists 3,760 studies for Multiple Myeloma across more than 10 countries. 769 are recruiting or about to start. 2,824 of them are mainly about Multiple Myeloma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Leukemia, Plasma Cell too: 3,773 studies, 775 open.
ClinicalTrials.gov finds 4,059 studies for Multiple Myeloma. How that becomes 3,758 here
This page counts the studies the registry files under Multiple Myeloma, and those it files under no condition that list Multiple Myelomathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 4,059Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −12Filed under a narrower condition, counted on its own pageLeukemia, Plasma Cell 11
- −59List Multiple Myeloma as a condition, but the registry did not file them under itMost often written as “Smoldering Multiple Myeloma” (30), “Smoldering Plasma Cell Myeloma” (10), and “Multiple Myeloma in Relapse” (3). The registry filed 2 of them under no condition at all, and the others under other conditions only, most often Smoldering Multiple Myeloma (44) and Monoclonal Gammopathy of Undetermined Significance (11).
- −230Match it another way82 name it in the title, 2 in a keyword, and 146 by a synonym or other text the search reads.
- 3,758The count on this page88 of them list Multiple Myeloma in their own words; the registry filed them under no condition.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Status
Who runs them
National Cancer Institute (NCI) (140) · Celgene (92) · Mayo Clinic (84) · Memorial Sloan Kettering Cancer Center (78) · Fred Hutchinson Cancer Center (72) · M.D. Anderson Cancer Center (67) · Janssen Research & Development, LLC (66) · University of Arkansas (55)
What is being tested here
Drugs under test in Multiple Myeloma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Corticosteroids 44 open · Proteasome inhibitors 24 open · Alkylating agents 19 open · Antibody-drug conjugates (ADCs) 16 open · Antimetabolites 6 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients · Phase 3 · The Affiliated People's Hospital of Ningbo University
- Dec 2026Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myeloma (COBRA) · Phase 3 · University of Chicago
- Dec 2026Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma · Phase 3 · ECOG-ACRIN Cancer Research Group
- Dec 2026Post-Op Pain Control for Prophylactic Intramedullary Nailing. · Phase 3 · St. Louis University
- Jan 2027A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) · Phase 3 · Celgene
- Mar 2027A Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combination With Lenalidomide and Dexamethasone in Patients With Refractory or Relapsed Multiple Myeloma · Phase 3 · Celltrion
- Mar 2027A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients · Phase 3 · Hangzhou Sumgen Biotech Co., Ltd.
- Apr 2027NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide · Phase 3 · PETHEMA Foundation
- Apr 2027A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant · Phase 3 · Sanofi
- Jul 2027A Study to Evaluate the Efficacy and Safety of HLX15-IV Versus DARZALEX® in Combination with Lenalidomide-Dexamethasone (Rd) in Transplant-ineligible Patients with Newly Diagnosed Multiple Myeloma · Phase 3 · Shanghai Henlius Biotech
Who these studies take
Of the 584 Multiple Myeloma studies recruiting now, 429 (73%) set no upper age limit and 106 (18%) stop at 75 or younger. 36 (6%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 24 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 29 (5%) | 29 (5%) |
| 18 | 545 (93%) | 545 (93%) |
| 30 | 560 (96%) | 560 (96%) |
| 40 | 562 (96%) | 562 (96%) |
| 50 | 565 (97%) | 565 (97%) |
| 65 | 576 (99%) | 576 (99%) |
| 75 | 545 (93%) | 545 (93%) |
| 85 | 456 (78%) | 456 (78%) |
Across all 3,760 studies, recruiting or not: 21% stop at 75 or younger and 6% at 65; 10% take children; <1% are for women only and <1% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Multiple Myeloma studies take
Of 505 phase 2 interventional studies under Multiple Myeloma, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 50 mo33–75 · 413 studies | 43 mo27–71 · 212 studies | 57 mo39–99 · 201 studies |
| Phase 1/2 | 65 mo44–92 · 201 studies | 64 mo42–90 · 98 studies | 67 mo46–94 · 103 studies |
| Phase 2 | 57 mo35–95 · 505 studies | 38 mo27–77 · 93 studies | 59 mo40–96 · 412 studies |
| Phase 3 | 56 mo35–95 · 178 studies | 45 mo31–66 · 107 studies | 87 mo48–108 · 71 studies |
| Phase 4 | 42 mo30–57 · 28 studies | — | — |
| Interventional, no phase | 38 mo20–79 · 186 studies | — | 37 mo21–81 · 172 studies |
| Observational | 61 mo30–126 · 239 studies | 49 mo28–70 · 66 studies | 70 mo33–… · 173 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting8
- BCMA Bispecific Antibody Therapy for Post-BCMA CAR T-Cell Therapy Relapse (RECLAIM)Nov 4, 2026NCT07009899
- FT836 CAR T-cell Therapy in Combination With Daratumumab in Patients With Relapsed and/or Refractory Multiple MyelomaNov 4, 2026NCT07221032
- Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe NeutropeniaNov 3, 2026NCT06323447
- IASO206 in Patients With Relapsed/Refractory Multiple MyelomaOct 27, 2026NCT07322159
- Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple MyelomaOct 26, 2026NCT04822337
Show 3 moreShow fewer
- Low-Dose TBI Plus CAR T-Cell Therapy for Relapsed/Refractory DLBCL and Multiple MyelomaOct 26, 2026NCT07725406
- Neurocognitive Trajectories After BCMA CAR-TOct 23, 2026NCT07740317
- A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).Oct 21, 2026NCT07735637
Results posted3
- Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple MyelomaNov 9, 2026NCT04091126
- Combination Treatment Therapy Approaches for the Treatment of High-Risk Multiple Myeloma, REACH TrialNov 2, 2026NCT05497804
- Cryocompression Therapy for Peripheral Neuropathy in Patients With Multiple MyelomaOct 13, 2026NCT03870451
Stopped2
- Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple MyelomaTerminatedNov 4, 2026NCT05996367
- A Multicentre, Non-Blinded Study Exploring Self-Administration of Chemotherapy in the Home EnvironmentTerminatedOct 28, 2026NCT04268199
Newly registered20
- BCMA/GPRC5D Dual-Target CAR-T Cell Immunotherapy for Relapsed/Refractory Multiple MyelomaNov 10, 2026NCT07927842
- A Study to Learn About a Medicine (Called Elranatamab) in People With Relapsed Refractory Multiple MyelomaNov 9, 2026NCT07927023
- A Study of MBS314 for Injection in Participants With Relapsed/Refractory Multiple Myeloma.Nov 3, 2026NCT07911748
- The Value of a Tailored-based, Exercise Program for Improving Quality of Life of Patients With Hematologic Malignancies: a Pilot Randomized TrialNov 3, 2026NCT07912684
- Phase 1 Study of 6MW5311 in Adults With Relapsed or Refractory Blood CancersNov 3, 2026NCT07914556
Show 15 moreShow fewer
- Study of CM336+CM313 Combination Therapy in Patients With Relapsed or Refractory Multiple MyelomaNov 2, 2026NCT07910903
- BCMA Polymorphisms in Patients With Multiple MyelomaOct 30, 2026NCT07906418
- Aspirin vs. Rivaroxaban for Thromboprophylaxis in Multiple MyelomaOct 30, 2026NCT07907211
- A Trial Comparing Ramantamig and Daratumumab (Ramantamig-D) Versus Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant EligibleOct 29, 2026NCT07903272
- To Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Autologous Stem Cell Transplant in Newly Diagnosed Multiple MyelomaOct 29, 2026NCT07903506
- QLS4131 for Relapsed/Refractory Multiple Myeloma With Extramedullary DiseaseOct 29, 2026NCT07903636
- Elranatamab With Mezigdomide and Dexamethasone in Patients With Relapsed/Refractory Multiple MyelomaOct 28, 2026NCT07901868
- Time-limited Treatment With Avatrombopag Pre- and Post-CAR T-cell Therapy to Prevent Post-CAR T-cell CytopeniasOct 26, 2026NCT07895017
- RE-RITE: Real-world Evaluation of Response, Implementation and Toxicity of ElranatamabOct 23, 2026NCT07891871
- Comparing Bispecific Antibody Treatment to Autologous Stem Cell Transplant for Newly Diagnosed, Standard Risk Multiple MyelomaOct 22, 2026NCT07887984
- A Trial to Evaluate Safety and Efficacy of Anitocabtagene Autoleucel Versus Standard of Care in Newly Diagnosed Multiple MyelomaOct 21, 2026NCT07887672
- Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic LeukemiaOct 20, 2026NCT07882069
- A Phase IV Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma That is Not Responding to Four or More Standard Treatments or Has Come Back After Several Standard TreatmentsOct 19, 2026NCT07881835
- Phase 1a/b Study of GPRC5D CART Therapy in Relapsed/Refractory Multiple Myeloma and Light-chain AmyloidosisOct 14, 2026NCT07874334
- Microbiome Intervention for CAR-T Optimization and Response (MICRO-CART)Oct 13, 2026NCT07871747
Studies
Recruiting first, then most recently updated. Showing 50 of 3,760. Browse all 3,760 → or search them.
- Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple MyelomaRecruitingNCT07555938Phase 318 countries
- REAL World IMROZ OutcomEs (REALIZE Study)Not yet recruitingNCT07889323
- A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple MyelomaRecruitingNCT05650632Phase 17 countries
- BCMA/GPRC5D Dual-Target CAR-T Cell Immunotherapy for Relapsed/Refractory Multiple MyelomaNot yet recruitingNCT07927842Phase 11 country
- 18F-Fluciclovine PET/CT in Multiple MyelomaRecruitingNCT06103838Phase 21 country
- Long-term Follow-up Study in Subjects With Multiple Myeloma Previously Treated With GC012F InjectionEnrolling by invitationNCT078330461 country
- A Study to Evaluate RO7851624 in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)RecruitingNCT07558915Phase 12 countries
- IASO206 in Patients With Relapsed/Refractory Multiple MyelomaRecruitingNCT07322159Early Phase 11 country
- Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple MyelomaRecruitingNCT05312255Not applicable1 country
- Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsRecruitingNCT026826671 country
- A Study to Learn About a Medicine (Called Elranatamab) in People With Relapsed Refractory Multiple MyelomaNot yet recruitingNCT07927023
- Belantamab Mafodotin or Daratumumab With Bortezomib, Lenalidomide and Dexamethasone for Newly Diagnosed Multiple MyelomaRecruitingNCT07285239Phase 31 country
- At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced CancerRecruitingNCT05969860Phase 21 country
- Engaging T-cells to Eliminate MRD in Newly Diagnosed Myeloma Optimizing Response With Talquetmab and Teclistamab (ROTATE)RecruitingNCT06993675Phase 21 country
- A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple MyelomaRecruitingNCT05730036Phase 318 countries
- Study of YKST02 in Adults With Relapsed or Refractory Multiple MyelomaNot yet recruitingNCT07695740Phase 21 country
- A Trial to Study if REGN17372 in Combination With Linvoseltamab is Tolerable for Adult Participants With Relapsed/Refractory Multiple MyelomaRecruitingNCT07455851Phase 1/22 countries
- Cevostamab in Combination With Pomalidomide and Dexamethasone After BCMA- Targeting CAR T-Cell Therapy in Participants With Previously Treated Multiple MyelomaRecruitingNCT07825064Phase 21 country
- A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)RecruitingNCT05927571Phase 13 countries
- A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple MyelomaRecruitingNCT05583617Phase 1/26 countries
- A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care TreatmentsRecruitingNCT05137054Phase 15 countries
- A Trial Comparing Ramantamig and Daratumumab (Ramantamig-D) Versus Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant EligibleNot yet recruitingNCT07903272Phase 3
- FT836 CAR T-cell Therapy in Combination With Daratumumab in Patients With Relapsed and/or Refractory Multiple MyelomaRecruitingNCT07221032Phase 11 country
- Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First RelapseRecruitingNCT06948084Phase 21 country
- A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)RecruitingNCT07222761Phase 38 countries
- Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain AmyloidosisRecruitingNCT06971380Phase 21 country
- A Study of MBS314 for Injection in Participants With Relapsed/Refractory Multiple Myeloma.Not yet recruitingNCT07911748Phase 1/2
- cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT053668811 country
- In VIVO CAR-T Therapy for Relapsed/Refractory Hematological MalignanciesRecruitingNCT07239323Phase 11 country
- BCMA Bispecific Antibody Therapy for Post-BCMA CAR T-Cell Therapy Relapse (RECLAIM)RecruitingNCT07009899Phase 21 country
- A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)RecruitingNCT07393282Phase 36 countries
- A Study to Evaluate Efficacy and Safety of Ciltacabtagene AutoleucelRecruitingNCT07149857Phase 23 countries
- The Value of a Tailored-based, Exercise Program for Improving Quality of Life of Patients With Hematologic Malignancies: a Pilot Randomized TrialRecruitingNCT07912684Not applicable1 country
- A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple MyelomaRecruitingNCT07258511Phase 315 countries
- A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple MyelomaRecruitingNCT07589634Phase 210 countries
- Phase 1 Study of 6MW5311 in Adults With Relapsed or Refractory Blood CancersRecruitingNCT07914556Phase 11 country
- Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell StudiesEnrolling by invitationNCT024737571 country
- A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) AmyloidosisRecruitingNCT05652335Phase 17 countries
- A Study of Ramantamig Plus Daratumumab Versus Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (DVRd) or Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With NDMM For Whom Stem Cell Transplant is Not PlannedRecruitingNCT07665450Phase 314 countries
- A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple MyelomaRecruitingNCT05552222Phase 325 countries
- Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe NeutropeniaRecruitingNCT063234472 countries
- A Study of Talquetamab in Participants With Relapsed or Refractory Multiple MyelomaRecruitingNCT04634552Phase 211 countries
- A Long-term Study for Participants Previously Treated With Ciltacabtagene AutoleucelRecruitingNCT05201781Phase 48 countries
- ELEVATE-MM: Elotuzumab, Iberdomide and Dexamethasone Post Idecabtagene Vicleucel in Relapsed and Refractory Multiple MyelomaRecruitingNCT06518551Phase 11 country
- Family Study of Lymphoproliferative DisordersRecruitingNCT006264961 country
- Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple MyelomaRecruitingNCT05091372Phase 21 country
- Study of CM336+CM313 Combination Therapy in Patients With Relapsed or Refractory Multiple MyelomaNot yet recruitingNCT07910903Phase 31 country
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesRecruitingNCT06904066Phase 11 country
- BCMA Polymorphisms in Patients With Multiple MyelomaNot yet recruitingNCT079064181 country
- Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)Not yet recruitingNCT07776964Not applicable1 country