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Vascular Malformations clinical trials

The registry lists 79 studies for Vascular Malformations across more than 10 countries. 33 are recruiting or about to start. 41 of them are mainly about Vascular Malformations (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Arteriovenous Fistula: 525 studies, 126 open.

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Status

Completed
27
Recruiting
22
Not yet recruiting
7
Status unknown
7
Terminated
5
Active, not recruiting
4

Phase

Phase 2
22
Phase 1
9
Phase 3
7
Phase 4
2

Where

United States
30
France
12
China
10
Germany
7
Canada
5
Netherlands
4

Who runs them

Shanghai Jiao Tong University School of Medicine (4) · Children's Hospital of Philadelphia (3) · Boston Children's Hospital (3) · Mayo Clinic (2) · University Hospital Erlangen (2) · Stanford University (2) · Centre hospitalier de l'Université de Montréal (CHUM) (2) · Radboud University Medical Center (2)

What is being tested here

Drugs under test in Vascular Malformations studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Everolimus202
Alpelisib202
Sirolimus125
Trametinib102
Bleomycin102
Topical Sirolimus102
Mirdametinib101
Enalapril101
Thalidomide003
Timolol002

Drug classes tested here mTOR inhibitors 3 open

Coming up

2phase 3 studies under way
7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 22 Vascular Malformations studies recruiting now, 13 (59%) set no upper age limit and 7 (32%) stop at 75 or younger. 15 (68%) take children under 18. 1 (5%) are for women only and 0 (0%) for men only; 3 (14%) take healthy volunteers.

Recruiting studies that take each age, of 22
AgeWomenMen
1014 (64%)14 (64%)
1821 (95%)20 (91%)
3021 (95%)20 (91%)
4019 (86%)18 (82%)
5018 (82%)18 (82%)
6518 (82%)18 (82%)
7515 (68%)15 (68%)
8515 (68%)15 (68%)

Across all 79 studies, recruiting or not: 27% stop at 75 or younger and 20% at 65; 63% take children; 5% are for women only and 0% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 79. Browse all 79 → or search them.