Drug
Olanzapine clinical trials
Also written Zyprexa and LY170053.
Includes 6 studies of Olanzapine hydrochloride.
- studies test it
- 266
- open now
- 22
- in phase 3
- 80
- first study started
- 1997
Keep track of what changes. Save the Olanzapine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Zyprexa
- 78
Studies by the year they started
264 studies that test it; most in 2003 (22)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 2 |
| 1999 | 1 |
| 2000 | 10 |
| 2001 | 9 |
| 2002 | 11 |
| 2003 | 22 |
| 2004 | 18 |
| 2005 | 14 |
| 2006 | 16 |
| 2007 | 11 |
| 2008 | 12 |
| 2009 | 9 |
| 2010 | 6 |
| 2011 | 6 |
| 2012 | 7 |
| 2013 | 5 |
| 2014 | 7 |
| 2015 | 8 |
| 2016 | 10 |
| 2017 | 12 |
| 2018 | 8 |
| 2019 | 5 |
| 2020 | 7 |
| 2021 | 6 |
| 2022 | 9 |
| 2023 | 7 |
| 2024 | 14 |
| 2025 | 5 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 32
- Phase 2
- 44
- Phase 3
- 80
- Phase 4
- 88
- No phase
- 32
What it is tested for
Each study’s main condition, where its own words name it.
- Nausea
- 17
Who runs them
Industry 83 · Other 183
Eli Lilly and Company (39) · Alkermes, Inc. (10) · Washington University School of Medicine (5) · New York State Psychiatric Institute (4) · Dr. Reddy's Laboratories Limited (4) · Centre for Addiction and Mental Health (3) · M.D. Anderson Cancer Center (3) · Mylan Pharmaceuticals Inc (3)
Often tested with
Tested in the same studies.
Risperidone (42) · Aripiprazole (26) · Quetiapine (19) · Ziprasidone (15) · Samidorphan (10) · Haloperidol (9) · Amisulpride (8) · Dexamethasone (6)
Studies
Open first, then newest update. How each study uses Olanzapine is read from its arms, and is right about nine times in ten.
Testing it · 266
- GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric CancerNot yet recruitingPhase 2University of Illinois at ChicagoNCT07581405Written as Olanzapine
- Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO TrialRecruitingPhase 2Roswell Park Cancer InstituteNCT06995508Written as Olanzapine
- Long-term Safety Extension Study of OLZ/SAM in Pediatric SubjectsEnrolling by invitationPhase 3Alkermes, Inc.NCT04987229Written as OLZ/SAM
- Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic MedicationsRecruitingPhase 3Minerva NeurosciencesNCT07565428Written as olanzapine
- Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung CancerRecruitingPhase 2OHSU Knight Cancer InstituteNCT05705492Written as Olanzapine
- Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative ChemotherapyRecruitingPhase 3Blokhin's Russian Cancer Research CenterNCT07633236Written as OLANZapine 2.5 MG
- Olanzapine Impact on First-line Immunotherapy for Advanced EGFR-negative NSCLCRecruitingPhase 2Second Affiliated Hospital of Nanchang UniversityNCT06554613Written as Olanzapine
- An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing CINV From Multi-Agent HECRecruitingPhase 4Shanghai 6th People's HospitalNCT07482891Written as Olanzapine
- Olanzapine Plus Metoclopramide for the Prevention of Opioid-Induced Nausea and VomitingRecruitingPhase 3Affiliated Hospital of Qinghai UniversityNCT07208305Written as Olanzapine
- "Extended" (Alternate Day) Antipsychotic DosingRecruitingPhase 4Centre for Addiction and Mental HealthNCT04478838Written as Olanzapine
- A Cohort Study on the Prevention of Nausea and Vomiting Induced by Concurrent Chemoradiotherapy for Lung Cancer Using Rolapitant and PalonosetronNot yet recruitingNot applicableHenan Cancer HospitalNCT07442890Written as Olanzapine
- Prevention of Delayed CINV After Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing RegimenRecruitingPhase 3The Affiliated People's Hospital of Ningbo UniversityNCT07413809Written as Olanzapine
- Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)RecruitingPhase 1/2First Affiliated Hospital of Chongqing Medical UniversityNCT05814640Written as Olanzapine
- Olanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic ChemotherapyNot yet recruitingPhase 3Shanghai Children's Medical CenterNCT07035821Written as Olanzapine Tablets
- Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac SurgeryRecruitingNot applicableRigshospitalet, DenmarkNCT05635227Written as Olanzapine 10 MG
- Olanzapine Versus Placebo for Moderately Emetogenic ChemotherapyRecruitingPhase 3Mahidol UniversityNCT06850454Written as olanzapine
- The Danish Out-of-Hospital Cardiac Arrest StudyRecruitingPhase 3Christian HassagerNCT05895838Written as Olanzapine
- Olanzapine 2.5 vs 5 mg in Quadruplet Nausea/Vomiting Prophylaxis Before High-Dose MelphalanRecruitingPhase 3Augusta UniversityNCT06588413Written as Olanzapine
- Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients with Advanced Stage CancerEnrolling by invitationPhase 2Englewood Hospital and Medical CenterNCT05170919Written as Olanzapine
- Olanzapine for Cancer Related Anorexia-cachexia SyndromeRecruitingPhase 3Mahidol UniversityNCT06517199Written as Olanzapine 2.5 MG
See all 266 studies that test Olanzapine →
Given in every arm · 17 — Olanzapine is usual care beside what is tested
- Olanzapine Based Dexamethasone-sparing Regimen for Breast Cancer Patients With Metabolic-risk FactorsRecruitingNot applicableAlexandria UniversityNCT07743827Written as olanzapine
- A Simplified Regimen to Prevent Nausea and Vomiting Using Netupitant/Palonosetron in Germ Cell Cancer Patients Receiving ChemotherapyNot yet recruitingEarly Phase 1Ottawa Hospital Research InstituteNCT07662200Written as Olanzapine
- NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC RegimensCompletedPhase 3Fudan UniversityNCT06331520Written as Olanzapine
- Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic ChemotherapyCompletedPhase 3Alliance for Clinical Trials in OncologyNCT03578081Written as Olanzapine
- A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic MedicationCompletedPhase 2Astellas Pharma Global Development, Inc.NCT03557931Written as olanzapine
- A Study of ALKS 3831 in Adults With SchizophreniaCompletedPhase 2Alkermes, Inc.NCT01903837Written as Olanzapine
- The Effect of CORT118335 on Olanzapine-Induced Weight GainCompletedPhase 1Corcept TherapeuticsNCT03877562Written as Olanzapine
- Telmisartan as an Adjunctive Treatment for Metabolic Problems in Patients With SchizophreniaCompletedPhase 4University of Massachusetts, WorcesterNCT00981526Written as Olanzapine
- Trial and Follow-up of the Efficacy of Two-stage Integrated Treatment for Chinese Schizophrenia InpatientsStatus unknownNot applicableGuangzhou Psychiatric HospitalNCT02850445Written as Olanzapine
- Study in Adolescents With Schizophrenia or Bipolar DisorderCompletedPhase 4Eli Lilly and CompanyNCT00982020Written as Olanzapine
- Tandospirone Combined With Atypical Antipsychotic Drugs in SchizophreniaStatus unknownPhase 4Qingyun YinNCT02040883Written as Risperidone/Olanzapine/Quetiapine/Ziprasidone/Aripiprazole
- Study of Pharmacotherapy of Psychotic DepressionCompletedPhase 3Weill Medical College of Cornell UniversityNCT00056472Written as Olanzapine
- A Study of Zonisamide to Prevent Olanzapine-Associated Weight GainCompletedPhase 3Lindner Center of HOPENCT00363376Written as olanzapine
- Efficacy and Safety of Olanzapine in the Extended Treatment for Manic or Mixed Episode of Bipolar I DisorderCompletedPhase 3Eli Lilly and CompanyNCT00266630Written as olanzapine
- Use, Effects and Side-effects of Second-generation Antipsychotics in a Naturalistic SettingCompletedPhase 4University of BergenNCT00932529Written as Olanzapine
- Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With OlanzapineCompletedPhase 3Eli Lilly and CompanyNCT00401973Written as olanzapine
- Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy HumansCompletedNot applicableLeiden University Medical CenterNCT00625170Written as olanzapine
As the comparator · 55 — what is tested is compared with Olanzapine
- Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I DisorderRecruitingPhase 3Alkermes, Inc.NCT05303064Written as Olanzapine
- Empagliflozin Addition in Modulating Metabolic Disturbances Associated With Olanzapine in Schizophrenia PatientsRecruitingPhase 3Tanta UniversityNCT05669742Written as olanzapine
- A Study of Olanzapine-Samidorphan Tablets in Adults With SchizophreniaNot yet recruitingPhase 3Qilu Pharmaceutical Co., Ltd.NCT06649214Written as Olanzapine
- A Study for Participants With SchizophreniaCompletedPhase 2Denovo Biopharma LLCNCT00520923Written as Olanzapine
- A Long-Term, Open-Label, Study on SchizophreniaTerminatedPhase 2/3Denovo Biopharma LLCNCT01129674Written as Olanzapine
- An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With SchizophreniaCompletedPhase 1Teva Branded Pharmaceutical Products R&D LLCNCT06315283Written as Oral olanzapine
- A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or SchizophreniformCompletedPhase 3Janssen Scientific Affairs, LLCNCT02431702Written as Olanzapine
- A Four-week Clinical Trial Investigating Efficacy and Safety of Cannabidiol As a Treatment for Acutely Ill Schizophrenic PatientsTerminatedPhase 2Central Institute of Mental Health, MannheimNCT02088060Written as Olanzapine
- 9 Week Extension Study of Asenapine and Olanzapine in Treatment of Mania (P07007)(COMPLETED)CompletedPhase 3Organon and CoNCT00143182Written as Olanzapine
- Efficacy and Safety of Asenapine With Placebo and Olanzapine (41022)(P05947)CompletedPhase 3Organon and CoNCT00151424Written as Olanzapine
- Efficacy and Safety of Asenapine With Placebo and Olanzapine (41021)(P05933)CompletedPhase 3Organon and CoNCT00156117Written as olanzapine
- 3-week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07009)CompletedPhase 3Organon and CoNCT00159796Written as Olanzapine
- Efficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (25543)(COMPLETED)(P05817)CompletedPhase 3Organon and CoNCT00212836Written as olanzapine
- Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25517)(P05935)CompletedPhase 3Organon and CoNCT00212784Written as olanzapine
- A Study of the Efficacy and Safety of Asenapine in Participants With an Acute Exacerbation of Schizophrenia (P05688)CompletedPhase 3Organon and CoNCT01617187Written as Olanzapine
- Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant PsychosisActive, not recruitingPhase 2Fundación Pública Andaluza para la gestión de la Investigación en SevillaNCT04529226Written as haloperidol, pimozide, olanzapine, risperidone, amisulpride
- Amisulpride Treatment for BPSD in AD PatientsStatus unknownNot applicableTianjin Anding HospitalNCT04341467Written as Olanzapine
- A Safety Study Comparing LY2140023 to Atypical Antipsychotic Standard Treatment in Schizophrenic PatientsCompletedPhase 2Denovo Biopharma LLCNCT00845026Written as olanzapine
- Long-Term Efficacy and Safety of Asenapine Using Olanzapine as a Positive Control (41512)(COMPLETED)(P05784)CompletedPhase 3Organon and CoNCT00156091Written as Olanzapine
- Efficacy and Safety of Asenapine Using an Active Control in Subjects With Schizophrenia or Schizoaffective Disorder (25520)(P05846)CompletedPhase 3Organon and CoNCT00212771Written as olanzapine
Showing 20 of 55.
Codes
What other systems call Olanzapine · ClinicalTrials.gg INT006653
- MeSH (NLM) D000077152OlanzapineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) N7U69T4SZROLANZAPINEConfirmed FDA, NLM, Wikidata
- RxNorm 61381Confirmed FDA, Wikidata
- Wikidata Q201872olanzapineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47639OlanzapineOne source FDA
- DrugBank DB00334One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077152 | Olanzapine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | N7U69T4SZR | OLANZAPINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 61381 | — | Confirmed FDA, Wikidata |
| Wikidata | Q201872 | olanzapine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47639 | Olanzapine | One source FDA |
| DrugBank | DB00334 | — | One source Wikidata |
Also registered as olanzapine pamoate (UNII X7S6Q4MHCB · RxNorm 885604).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.