Nausea clinical trials
The registry lists 644 studies for Nausea across more than 10 countries. 85 are recruiting or about to start. 257 of them are mainly about Nausea (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Postoperative Nausea and Vomiting too: 1,219 studies, 192 open.
ClinicalTrials.gov finds 1,596 studies for Nausea. How that becomes 644 here
This page counts the studies the registry files under Nausea, and those it files under no condition that list Nauseathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,596Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −573Filed under a narrower condition, counted on its own pagePostoperative Nausea and Vomiting 571
- −172List Nausea as a condition, but the registry did not file them under itMost often written as “Chemotherapy-induced Nausea and Vomiting” (85), “Chemotherapy Induced Nausea and Vomiting” (14), and “Chemotherapy-Induced Nausea and Vomiting (CINV)” (13). The registry filed them under other conditions only, most often Vomiting (161) and Neoplasms (15).
- −207Match it another way191 name it in the title and 16 in a keyword.
- 644The count on this page15 of them list Nausea in their own words; the registry filed them under no condition.
Get an email when these change. Save the Nausea studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
GlaxoSmithKline (18) · M.D. Anderson Cancer Center (15) · Merck Sharp & Dohme LLC (10) · Pfizer (7) · Second Affiliated Hospital, School of Medicine, Zhejiang University (7) · University of Rochester (5) · Wake Forest University Health Sciences (5) · Yonsei University (5)
What is being tested here
Drugs under test in Nausea studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Rimegepant | 3 | 3 | 3 |
| Olanzapine | 2 | 9 | 18 |
| Fosaprepitant | 2 | 2 | 9 |
| Aprepitant | 1 | 3 | 39 |
| Palonosetron | 1 | 4 | 22 |
| Metoclopramide | 1 | 6 | 18 |
| Ginger extract | 1 | 2 | 7 |
| Tradipitant | 1 | 3 | 4 |
| Propofol | 1 | 0 | 4 |
| Dexmedetomidine | 1 | 0 | 3 |
Drug classes tested here Antiemetics 6 open · NK1 receptor antagonists 3 open · CGRP receptor antagonists 3 open · 5-HT3 antagonists 2 open · Antipsychotics 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use · Phase 3 · Vanda Pharmaceuticals
- Dec 2026Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Gemcitabine Combined With Paclitaxel Protein-bound · Phase 3 · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Dec 2026Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Trastuzumab Deruxtecan · Phase 3 · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Dec 2026Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Docetaxel Plus Cyclophosphamide · Phase 3 · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Jan 2027Electroacupuncture Plus Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer · Phase 3 · Feixue Song
- Mar 2027Antiemetic Fosaprepitant To Remedy Nausea and Vomiting · Phase 3 · Montefiore Medical Center
- Jun 2027Inhaled Isopropyl Alcohol for Treatment of Nausea · Phase 3 · State University of New York at Buffalo
- Oct 2027Olanzapine 2.5 vs 5 mg in Quadruplet Nausea/Vomiting Prophylaxis Before High-Dose Melphalan · Phase 3 · Augusta University
- Oct 2027Domperidone in Treating Patients With Gastrointestinal Disorders · Phase 3 · M.D. Anderson Cancer Center
- Nov 2026Virtual Reality (VR) Based Relaxation for Nausea and Comfort in Pregnancy · Filiz Keskin
Who these studies take
Of the 51 Nausea studies recruiting now, 21 (41%) set no upper age limit and 19 (37%) stop at 75 or younger. 10 (20%) take children under 18. 5 (10%) are for women only and 0 (0%) for men only; 13 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (12%) | 6 (12%) |
| 18 | 44 (86%) | 40 (78%) |
| 30 | 44 (86%) | 39 (76%) |
| 40 | 44 (86%) | 39 (76%) |
| 50 | 42 (82%) | 39 (76%) |
| 65 | 43 (84%) | 40 (78%) |
| 75 | 38 (75%) | 35 (69%) |
| 85 | 31 (61%) | 28 (55%) |
Across all 644 studies, recruiting or not: 43% stop at 75 or younger and 34% at 65; 15% take children; 20% are for women only and 1% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nausea studies take
Of 43 phase 3 interventional studies under Nausea, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 4 mo2–8 · 18 studies | — | — |
| Phase 2 | 24 mo12–43 · 34 studies | — | — |
| Phase 3 | 26 mo12–51 · 43 studies | — | — |
| Phase 4 | 12 mo7–24 · 27 studies | — | — |
| Interventional, no phase | 13 mo5–28 · 126 studies | — | 13 mo6–28 · 120 studies |
| Observational | 33 mo15–48 · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered5
- Netupitant/Palonosetron for Prevention of Nausea and Vomiting in Breast Cancer ADC TherapyNov 5, 2026NCT07918079
- A Study to Evaluate the Effects of a Supplement on Gut Comfort in GLP-1 Receptor Agonist UsersOct 27, 2026NCT07898189
- Reiki After Bariatric SurgeryOct 21, 2026NCT07887035
- Vagal Auricular Stimulation for Motion SicknessOct 14, 2026NCT07873164
- HR20013 for the Prevention of Nausea and Vomiting in Patients With Cancer: A Real-World StudyOct 14, 2026NCT07874308
Studies
Recruiting first, then most recently updated. Showing 50 of 644. Browse all 644 → or search them.
- Study on Hydrotalcite for Relief of Acid Symptoms Due to Acid Rebound After Stopping Long-Term PPI TherapyRecruitingNCT072917001 country
- BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to OndansetronRecruitingNCT04150614Phase 41 country
- Netupitant/Palonosetron for Prevention of Nausea and Vomiting in Breast Cancer ADC TherapyNot yet recruitingNCT07918079Phase 2
- A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With CancerRecruitingNCT07169851Phase 210 countries
- Randomized Study in Children and Adolescents With Migraine: Acute TreatmentRecruitingNCT04649242Phase 39 countries
- Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of MigraineRecruitingNCT04743141Phase 33 countries
- Diagnostic and Psychometric Validation of the FRENCH HELP Scale in Hyperemesis GravidarumNot yet recruitingNCT077670711 country
- Vagal Auricular Stimulation for Motion SicknessNot yet recruitingNCT07873164Not applicable1 country
- Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy VolunteersRecruitingNCT07681076Phase 41 country
- HR20013 for the Prevention of Nausea and Vomiting in Patients With Cancer: A Real-World StudyRecruitingNCT078743081 country
- Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric SubjectsRecruitingNCT05156398Phase 37 countries
- Granisetron Use, Blood Pressure, and Nausea and Vomiting During Cesarean Delivery Under Spinal AnesthesiaNot yet recruitingNCT078617371 country
- Hypnosis for Pain and Nausea Reduction in Scoliosis Surgery: An Interventional StudyRecruitingNCT07854951Not applicable1 country
- Chinese Herbal Acupoint Application Combined With Triple Antiemetic Therapy for Prevention of Chemotherapy-Induced Nausea and Vomiting in Breast CancerNot yet recruitingNCT07848984Phase 21 country
- GDF-15 and Its Relationship With Treatment-related ADverse Events in Breast CancerNot yet recruitingNCT07465172Not applicable3 countries
- Study With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC)RecruitingNCT06904235Phase 24 countries
- Inhaled Isopropyl Alcohol for Treatment of NauseaRecruitingNCT05418244Phase 2/31 country
- Hyperemesis Gravidarum Risk Reduction With MetforminRecruitingNCT07129473Phase 1/21 country
- Evaluating Whether a Nausea Band Reduces Symptoms in Those With Chronic Nausea VomitingRecruitingNCT07720323Not applicable1 country
- Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Trastuzumab DeruxtecanRecruitingNCT07716189Phase 31 country
- Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Gemcitabine Combined With Paclitaxel Protein-boundRecruitingNCT07716228Phase 31 country
- Auricular Point Stimulation Plus Dexamethasone Versus Standard Antiemetic Regimen for Nausea and Vomiting Caused by Docetaxel Plus CyclophosphamideRecruitingNCT07716176Phase 31 country
- Fosrolapitant and Palonosetron for the Prevention of Antibody-drug Conjugate-induced Nausea and VomitingNot yet recruitingNCT07692451Phase 2
- The Antiemetic Effects of Increased Splanchnic Perfusion, Induced by the Gut Hormone GIP, in Healthy IndividualsEnrolling by invitationNCT07687589Not applicable1 country
- Broadening Antiemetics Research by Comparing the Effectiveness of Fosaprepitant and MetoclopramideNot yet recruitingNCT06740812Phase 41 country
- Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic TreatmentRecruitingNCT06543316Not applicable1 country
- Efficacy and Safety of Non Invasive Vagal Stimulation to Prevent Chemotherapy-induced NauseaRecruitingNCT04937309Not applicable1 country
- GI Neuromuscular Pathology Prospective RegistryRecruitingNCT021650591 country
- Indiana University Gastric Electrical Stimulation RegistryEnrolling by invitationNCT050472891 country
- Medical Cannabis Observational Study for Antiemetic Intervention in ChemotherapyNot yet recruitingNCT073749391 country
- Exploring the Role of taVNS in Nausea ManagementRecruitingNCT07632456Not applicable1 country
- Antiemetic Fosaprepitant To Remedy Nausea and VomitingRecruitingNCT06382012Phase 2/31 country
- Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)RecruitingNCT06464926Not applicable5 countries
- Serious Gaming for Chemotherapy-induced Nausea and VomitingRecruitingNCT05838638Not applicable1 country
- Dexmedetomidine and Propofol for Sedation in Cataract Surgery.RecruitingNCT07556133Not applicable1 country
- Olanzapine Plus Metoclopramide for the Prevention of Opioid-Induced Nausea and VomitingRecruitingNCT07208305Phase 31 country
- A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist UseRecruitingNCT07446439Phase 31 country
- Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Docetaxel Plus CyclophosphamideRecruitingNCT07537699Phase 21 country
- Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Trastuzumab DeruxtecanRecruitingNCT07537673Phase 21 country
- Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Gemcitabine Plus PaclitaxelRecruitingNCT07537660Phase 21 country
- Preoperative Oral Hydration in the Ambulatory Arthroplasty PopulationRecruitingNCT05520593Not applicable1 country
- Virtual Reality (VR) Based Relaxation for Nausea and Comfort in PregnancyEnrolling by invitationNCT07503080Not applicable1 country
- Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and VomitingRecruitingNCT07378839Not applicable1 country
- Effect of Aprepitant on Post-operative Nausea and Vomiting in Otologic SurgeryNot yet recruitingNCT07371728Phase 41 country
- ERAS-Based Preoperative Nutrition and Fasting in Total Knee ArthroplastyRecruitingNCT07336160Not applicable1 country
- Co-Development and Validation of Colonic Symptom Pictograms for Young PeopleNot yet recruitingNCT07337343
- Thumbtack Needle in the Treatment of NVPRecruitingNCT06566274Not applicable1 country
- Effect of Cardamom and Peppermint Oils on Chemotherapy-Related Nausea-Vomiting and Food IntakeNot yet recruitingNCT07318779Not applicable1 country
- EMDR Treatment of Conditioned Nausea and Vomiting in Cancer SurvivorsRecruitingNCT06769165Not applicable1 country
- Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.Not yet recruitingNCT07187427Not applicable1 country