Alcoholism clinical trials
The registry lists 1,674 studies for Alcoholism across more than 10 countries. 331 are recruiting or about to start. 1,296 of them are mainly about Alcoholism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 1,696 studies for Alcoholism. How that becomes 1,673 here
This page counts the studies the registry files under Alcoholism, and those it files under no condition that list Alcoholismthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,696Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −3List Alcoholism as a condition, but the registry did not file them under itMost often written as “Concurrent Alcohol Dependence and Pathological Gambling” (1), “Family History of Alcoholism” (1), and “Effects of Family History of Alcoholism and Sex on Alcohol Analgesia” (1). The registry filed them under other conditions only, most often Gambling (1) and Schizophrenia (1).
- −20Match it another way17 name it in the title, 2 in a keyword, and 1 by a synonym or other text the search reads.
- 1,673The count on this page2 of them list Alcoholism in their own words; the registry filed them under no condition.
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What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
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Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
Yale University (93) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (70) · VA Office of Research and Development (47) · Medical University of South Carolina (45) · Brown University (31) · University of Pennsylvania (28) · Centre for Addiction and Mental Health (22) · UConn Health (21)
What is being tested here
Drugs under test in Alcoholism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Psilocybin | 8 | 1 | 17 |
| Ethanol | 7 | 1 | 19 |
| Tirzepatide | 6 | 0 | 6 |
| Naltrexone | 5 | 22 | 95 |
| Semaglutide | 5 | 1 | 11 |
| Ketamine | 5 | 0 | 10 |
| Cannabidiol | 4 | 2 | 12 |
| Suvorexant | 4 | 0 | 7 |
| Acetylcysteine | 2 | 0 | 12 |
| Disulfiram | 2 | 0 | 7 |
Drug classes tested here GLP-1 receptor agonists 11 open · Psychedelics 10 open · Serotonin receptor agonists 9 open · Opioid antagonists 5 open · Anxiolytics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Effects of Ketone Supplementation on Acute Alcohol Withdrawal · Phase 3 · University of Pennsylvania
- Dec 2026Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder · Phase 3 · University of Pennsylvania
- Dec 2026Ketone Ester Intervention in Alcohol Use Disorder · Phase 3 · University of Pennsylvania
- Jan 2027Electronic Harm Reduction Treatment for Alcohol · Phase 3 · University of Washington
- Mar 2027Efficacy of Simvastatin in Alcoholic Liver Fibrosis · Phase 3 · Anna Cruceta
- Apr 2027Alcohol Use Disorder and Cannabidiol · Phase 3 · University of Colorado, Denver
- Apr 2027Evaluate the Efficacy and Safety of Naltrexone Hydrochloride Implant in Patients With Alcohol Use Disorder · Phase 3 · Shenzhen Sciencare Medical Industries Co., Ltd.
- Nov 2026Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building · University of Rhode Island
- Nov 2026PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD) · Nathan Brashares Sackett
- Nov 2026SER-ABS-AUD: Neuropsychosocial-Spiritual Correlates of Serene Abstinence in Adults With AUD · Grigore T. Popa University of Medicine and Pharmacy
Who these studies take
Of the 239 Alcoholism studies recruiting now, 84 (35%) set no upper age limit and 133 (56%) stop at 75 or younger. 11 (5%) take children under 18. 3 (1%) are for women only and 6 (3%) for men only; 64 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (1%) | 3 (1%) |
| 18 | 166 (69%) | 169 (71%) |
| 30 | 218 (91%) | 221 (92%) |
| 40 | 213 (89%) | 216 (90%) |
| 50 | 214 (90%) | 217 (91%) |
| 65 | 184 (77%) | 186 (78%) |
| 75 | 112 (47%) | 113 (47%) |
| 85 | 95 (40%) | 96 (40%) |
Across all 1,674 studies, recruiting or not: 61% stop at 75 or younger and 50% at 65; 7% take children; 2% are for women only and 4% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Alcoholism studies take
Of 134 phase 2 interventional studies under Alcoholism, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 28 mo19–48 · 75 studies | — | 34 mo21–49 · 63 studies |
| Phase 1/2 | 32 mo27–76 · 22 studies | — | — |
| Phase 2 | 33 mo21–59 · 134 studies | — | 35 mo23–59 · 122 studies |
| Phase 3 | 36 mo17–54 · 25 studies | — | — |
| Phase 4 | 58 mo49–83 · 24 studies | — | — |
| Interventional, no phase | 33 mo17–53 · 493 studies | — | 35 mo18–55 · 470 studies |
| Observational | 40 mo21–65 · 76 studies | — | 45 mo21–65 · 74 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting9
- Trial Phase: Syndemic Adapted Medly UgandaNov 6, 2026NCT07525271
- Study on Thiamine Supplementation to REduce braiN Injury Associated With Chronic Alcohol Use in Outpatients With Alcohol Use DisorderNov 6, 2026NCT07844720
- Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use OutcomesNov 4, 2026NCT07772960
- Coordinated Care for Alcohol ProblemsNov 3, 2026NCT07260149
- Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use DisorderOct 26, 2026NCT07405606
Show 4 moreShow fewer
- Elastography-based Brief Alcohol Intervention in Hospitalized IndividualsOct 22, 2026NCT07637539
- Peer Support in Alcohol DependenceOct 21, 2026NCT06381609
- Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use DisorderOct 21, 2026NCT06807918
- High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot StudyOct 16, 2026NCT07227545
Results posted2
- PRACT to Investigate Controlling Alcohol Related Harms in a Low-Income Setting; Emergency Department BIs in TanzaniaNov 4, 2026NCT04535011
- Pilot rTMS for AUD+mTBIOct 30, 2026NCT03995173
Stopped2
- Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2TerminatedNov 6, 2026NCT06006143
- Pilot rTMS for AUD+mTBITerminatedOct 30, 2026NCT03995173
Newly registered8
- Emotional Reactivity in Severe Alcohol Use Disorder and Major Depressive Disorder Using Eye-tracking, Physiological, and Interoceptive Measures (ERAD)Nov 9, 2026NCT07925281
- A MRT to Optimize a JITAI for Alcohol Craving and Suicide IdeationNov 6, 2026NCT07922590
- Effects of C-Tactile-optimal Touch on Alcohol Craving and Relapse-Related Biomarkers in Alcohol Use DisorderNov 5, 2026NCT07920601
- N-Acetylcysteine for Bipolar and Alcohol Use DisordersNov 3, 2026NCT07913542
- Connecting Online Military Personnel to Alcohol Harm-reducing Smartphone Support StudyNov 2, 2026NCT07911345
Show 3 moreShow fewer
- Investigation of the Gut-Brain Axis in Alcohol Use DisorderOct 29, 2026NCT07902635
- Disease Intervention Specialist (DIS) for SUDOct 15, 2026NCT07875361
- Recovery Management Checkup Scalability and Sustainability Hybrid ExperimentOct 14, 2026NCT07873944
Studies
Recruiting first, then most recently updated. Showing 50 of 1,674. Browse all 1,674 → or search them.
- Environment and Alcohol: A Pilot StudyRecruitingNCT06860607Phase 11 country
- SMART-r: Substance Monitoring and Active Relapse Tracking RepositoryRecruitingNCT066760591 country
- Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase PsychosisRecruitingNCT07056894Not applicable1 country
- Emotional Reactivity in Severe Alcohol Use Disorder and Major Depressive Disorder Using Eye-tracking, Physiological, and Interoceptive Measures (ERAD)RecruitingNCT079252811 country
- Spironolactone in Alcohol Use Disorder (SAUD)RecruitingNCT05807139Phase 11 country
- Addictions Neuroclinical Assessment (ANA)Enrolling by invitationNCT049468511 country
- A MRT to Optimize a JITAI for Alcohol Craving and Suicide IdeationNot yet recruitingNCT07922590Not applicable1 country
- Trial Phase: Syndemic Adapted Medly UgandaRecruitingNCT07525271Not applicable1 country
- Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making.Not yet recruitingNCT07842588Not applicable
- Study on Thiamine Supplementation to REduce braiN Injury Associated With Chronic Alcohol Use in Outpatients With Alcohol Use DisorderRecruitingNCT07844720Phase 21 country
- Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use DisorderRecruitingNCT06559995Phase 2/31 country
- NIAAA Natural History ProtocolRecruitingNCT022318401 country
- Disease Intervention Specialist (DIS) for SUDNot yet recruitingNCT078753611 country
- Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use OutcomesRecruitingNCT07772960Phase 11 country
- Sex Differences in the Response to Abstinence From Alcohol.RecruitingNCT03827460Phase 11 country
- Deaf CBT-TS to Reduce Suicide RiskNot yet recruitingNCT07279363Not applicable1 country
- eTSF for Latinx Young Adults With Alcohol Use DisorderNot yet recruitingNCT06722690Not applicable
- A Study of Brenipatide in Participants With Alcohol Use DisorderRecruitingNCT07219953Phase 38 countries
- N-Acetylcysteine for Bipolar and Alcohol Use DisordersNot yet recruitingNCT07913542Phase 21 country
- Imaging Mitochondrial Complex-I in Alcohol Use DisorderRecruitingNCT07825818Early Phase 11 country
- Coordinated Care for Alcohol ProblemsRecruitingNCT07260149Not applicable1 country
- Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and CravingRecruitingNCT07148843Phase 2/31 country
- Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7Not yet recruitingNCT075518301 country
- Connecting Online Military Personnel to Alcohol Harm-reducing Smartphone Support StudyNot yet recruitingNCT07911345Not applicable
- Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use DisorderRecruitingNCT06269627Phase 41 country
- Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)RecruitingNCT07027839Phase 11 country
- Tdcs And cogNitive traininG cOmbined for AUD (TANGO)RecruitingNCT05062369Not applicable1 country
- Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized PatientsNot yet recruitingNCT07810946Phase 1/21 country
- Phase 2 Study of Apremilast in Women and Men With Alcohol Use DisorderRecruitingNCT07029529Phase 21 country
- Developing a Novel Human Laboratory Paradigm for AUD Medication ScreeningRecruitingNCT06489782Not applicable1 country
- Investigation of the Gut-Brain Axis in Alcohol Use DisorderNot yet recruitingNCT07902635Not applicable1 country
- QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)Not yet recruitingNCT07661823Not applicable1 country
- Peer Support for Liver Transplant Recipients With History of ALDRecruitingNCT07397598Not applicable1 country
- Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)RecruitingNCT07216872Not applicable3 countries
- PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use DisorderRecruitingNCT06795581Phase 11 country
- Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use DisorderRecruitingNCT07405606Phase 21 country
- Effects of Olfactory Stimuli in Virtual Reality Cue Exposure on Craving and Attentional Bias in Alcohol Use DisorderNot yet recruitingNCT07667790Not applicable1 country
- Elastography-based Brief Alcohol Intervention in Hospitalized IndividualsRecruitingNCT07637539Not applicable1 country
- Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use DisorderRecruitingNCT06807918Phase 2/31 country
- Peer Support in Alcohol DependenceRecruitingNCT06381609Not applicable1 country
- Suvorexant for Alcohol Use Disorder (AUD): Neural MechanismsRecruitingNCT06484075Phase 1/21 country
- A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their PartnersRecruitingNCT05619185Not applicable1 country
- AAT for Alcohol Use Disorder in VeteransRecruitingNCT05372029Not applicable1 country
- High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot StudyRecruitingNCT07227545Not applicable1 country
- Suvorexant for Treatment of AUD and PTSDRecruitingNCT06679062Phase 21 country
- Recovery Management Checkup Scalability and Sustainability Hybrid ExperimentNot yet recruitingNCT07873944Phase 31 country
- Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)RecruitingNCT07559500Phase 11 country
- Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)RecruitingNCT056773211 country
- Self-administered Neurostimulation Intervention for Firefighter Traumatic Stress to Reduce Alcohol Use: Pilot StudyNot yet recruitingNCT07868055Not applicable
- Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use DisorderNot yet recruitingNCT07296094Phase 21 country