Selective Serotonin Reuptake Inhibitors: all 1,366 studies that test it
Page 1 of 14. Open to participants first (105), then studies with results posted, then the rest; newest registration first within each.
- Estimation of Control Before and After Treatment of a Depressive Episode With Serotonin Reuptake InhibitorsNot yet recruitingNCT07716982Not applicable
- Antidepressant Therapy for Improved Blood Vessel Health After PreeclampsiaRecruitingNCT07715669Early Phase 1
- Using Fenfluramine to Test the Serotonin Deficiency Theory of DepressionNot yet recruitingNCT07651293Not applicable
- Sertraline Combined With Multi-Strain Probiotics for Adolescent DepressionRecruitingNCT07645157Phase 2
- Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative ChemotherapyRecruitingNCT07633236Phase 3
- GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric CancerNot yet recruitingNCT07581405Phase 2
- Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic MedicationsRecruitingNCT07565428Phase 3
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingNCT07542756Phase 4
- A Phase 3 Study of Fenfluramine Hydrochloride in Rett SyndromeRecruitingNCT07503444Phase 3
- An Exploratory Study on Efficacy and Safety of Fosaprepitant and Palonosetron Hydrochloride for Injection in Preventing CINV From Multi-Agent HECRecruitingNCT07482891Phase 4
- Efficacy and Mechanisms of Escitalopram in Drug-Naïve First-Episode Major Depressive DisorderRecruitingNCT07480525Not applicable
- TDM-Guided Treatment With SSRIs in Hospitalized Adults and ChildrenRecruitingNCT07478796Phase 4
- Fluoxetine and Understanding Social ExperiencesNot yet recruitingNCT07456501Not applicable
- A Cohort Study on the Prevention of Nausea and Vomiting Induced by Concurrent Chemoradiotherapy for Lung Cancer Using Rolapitant and PalonosetronNot yet recruitingNCT07442890Not applicable
- Fluoxetine on Emotional Experience (FLEX) StudyRecruitingNCT07424781Not applicable
- Prevention of Delayed CINV After Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing RegimenRecruitingNCT07413809Phase 3
- sElective Serotonin reuPtake inhibitoRs In posT-covid After COVID-19RecruitingNCT07359482Phase 3
- Vortioxetine for Newly Diagnosed GlioblastomaRecruitingNCT07284628Phase 2
- RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)RecruitingNCT07266545Phase 4
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingNCT07210606Phase 4
- Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ)RecruitingNCT07210112Phase 2
- Olanzapine Plus Metoclopramide for the Prevention of Opioid-Induced Nausea and VomitingRecruitingNCT07208305Phase 3
- A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive DisorderRecruitingNCT07204314Phase 3
- SSRI Antidepressant Fluoxetine Improving Immunotherapy Efficacy in Advanced Hepatobiliary Malignancy Patients With Depression and AnxietyRecruitingNCT07174947Phase 2
- Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia SymptomsRecruitingNCT07136415Phase 4
- The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome ProjectRecruitingNCT07112365Phase 4
- Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in NigeriaNot yet recruitingNCT07110831Phase 4
- Comparison of the Efficacy and Safety of Dapoxetine, Kegel Exercises, and Acupuncture in the Treatment of Premature Ejaculation: A Randomized, Double-Blind, Placebo-Controlled TrialNot yet recruitingNCT07067970Not applicable
- Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination Therapy Versus MonotherapyNot yet recruitingNCT07057011Not applicable
- Olanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic ChemotherapyNot yet recruitingNCT07035821Phase 3
- Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression(SMART-I)Not yet recruitingNCT07011693Phase 4
- Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO TrialRecruitingNCT06995508Phase 2
- Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)RecruitingNCT06983080Phase 2
- Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac SurgeryRecruitingNCT06969287Phase 3
- Pupillometry in Delayed Sleep Wake Phase DisorderRecruitingNCT06949644Not applicable
- Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory DepressionRecruitingNCT06898606Phase 1/2
- Olanzapine Versus Placebo for Moderately Emetogenic ChemotherapyRecruitingNCT06850454Phase 3
- Neuroimaging of Escitalopram in Autism Spectrum DisorderEnrolling by invitationNCT06826326Phase 2
- Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson DiseaseNot yet recruitingNCT06805266Phase 4
- Neuroregulators for the Treatment of Diseases Associated With Esophageal-brain-gut Axis Communication Abnormalities.RecruitingNCT06778824Not applicable
- Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric DisorderRecruitingNCT06704594Phase 4
- Effort and Antidepressant Study TestNot yet recruitingNCT06696482Phase 1/2
- Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed PeopleRecruitingNCT06675851Phase 4
- Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal DementiaRecruitingNCT06604520Phase 2
- Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of AgeRecruitingNCT06598449Phase 4
- Olanzapine 2.5 vs 5 mg in Quadruplet Nausea/Vomiting Prophylaxis Before High-Dose MelphalanRecruitingNCT06588413Phase 3
- Olanzapine Impact on First-line Immunotherapy for Advanced EGFR-negative NSCLCRecruitingNCT06554613Phase 2
- Quetiapine Versus Trazadone in Women With Postpartum DepressionNot yet recruitingNCT06546358Early Phase 1
- Olanzapine for Cancer Related Anorexia-cachexia SyndromeRecruitingNCT06517199Phase 3
- Evaluation of Fluoxetine for Refractory Constipation With Somatic Symptom Disorder FeaturesNot yet recruitingNCT06506136Phase 2
- Nutrition Impact on Immunotherapy of CancerRecruitingNCT06500234Phase 3
- 7T Amygdala and Citalopram StudyRecruitingNCT06412315Not applicable
- ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in DepressionRecruitingNCT06408246Phase 2
- The Friendship Bench Plus TrialRecruitingNCT06384209Not applicable
- Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung CancerRecruitingNCT06338683Phase 3
- Trazodone on OSA EndotypesRecruitingNCT06286189Phase 1/2
- Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in InsomniaRecruitingNCT06281756Early Phase 1
- Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal CancerRecruitingNCT06225011Phase 1
- Escitalopram in Asthma Patients With Frequent ExacerbationRecruitingNCT06216535Phase 2
- The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes MellitusNot yet recruitingNCT06203275Phase 3
- Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental DisordersRecruitingNCT06081348Phase 2
- Psychopharmacotherapy for Depressive PatientsRecruitingNCT06054321Not applicable
- Can Immediate Post-injury Fluoxetine Improve the Recovery Trajectories of Victims in Bodily Trauma?RecruitingNCT06046859Phase 4
- Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth SyndromeRecruitingNCT06025474Phase 3
- Identifying and Treating Depression in the Orthopaedic Trauma PopulationRecruitingNCT05976347Phase 4
- The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingNCT05973851Phase 3
- The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingNCT05973786Phase 3
- Human Cerebral Blood Flow and SerotoninNot yet recruitingNCT05957094Not applicable
- The Danish Out-of-Hospital Cardiac Arrest StudyRecruitingNCT05895838Phase 3
- Establishing Multimodal Brain Biomarkers for Treatment Selection in DepressionRecruitingNCT05892744Phase 4
- Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)RecruitingNCT05814640Phase 1/2
- Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung CancerRecruitingNCT05705492Phase 2
- Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social AnxietyRecruitingNCT05683223Not applicable
- Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac SurgeryRecruitingNCT05635227Not applicable
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment FailureRecruitingNCT05603104Phase 3
- Home Transcutaneous Electrical Acustimulation (TEA)RecruitingNCT05519683Phase 2/3
- Chinese Longitudinal and Systematic Study of Bioplar DisorderRecruitingNCT05480150Not applicable
- Rapid Improvement of Depression of Fluoxetine Combined With ATPRecruitingNCT05431413Phase 2
- Study on the Optimal Diagnosis and Treatment Strategy of Major Depressive Disorder Based on AnhedoniaRecruitingNCT05389046Not applicable
- Intradermal Needle Therapy for Major Depressive DisorderNot yet recruitingNCT05352113Not applicable
- Rescue Pharmacotherapy for OSARecruitingNCT05293600Phase 1/2
- Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With TrazodoneRecruitingNCT05282550Phase 2
- Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients with Advanced Stage CancerEnrolling by invitationNCT05170919Phase 2
- Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)RecruitingNCT05041907Phase 2
- SSRIs and TDCS Enhance Post-stroke Motor RecoveryNot yet recruitingNCT05041582Phase 3
- Aβ Dynamics in LLMDRecruitingNCT05004987Phase 4
- Long-term Safety Extension Study of OLZ/SAM in Pediatric SubjectsEnrolling by invitationNCT04987229Phase 3
- Study of Dextromethorphan in OCD and Related DisordersRecruitingNCT04899687Phase 2
- Cognitive Effects of Adjuvant Vortioxetine in Early SchizophreniaRecruitingNCT04895488Phase 2/3
- Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)RecruitingNCT04623099Phase 4
- Pragmatic Trial of Obsessive-compulsive DisorderRecruitingNCT04539951Phase 2
- "Extended" (Alternate Day) Antipsychotic DosingRecruitingNCT04478838Phase 4
- Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised TrialRecruitingNCT04302870Phase 2/3
- Tolerability, Safety and Efficacy of VortioxetineRecruitingNCT04301492Phase 4
- Treatment of Refractory Infantile Spasms With FenfluramineRecruitingNCT04289467Phase 2
- Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)RecruitingNCT04245748Phase 4
- Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)RecruitingNCT04245436Phase 4
- Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.RecruitingNCT04221997Phase 4
- Escitalopram and Language Intervention for Subacute AphasiaRecruitingNCT03843463Phase 2
- A Study Utilizing Escitalopram in Glioma PatientsRecruitingNCT03728673Phase 2