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Post-Dural Puncture Headache clinical trials

The registry lists 122 studies for Post-Dural Puncture Headache across more than 10 countries. 27 are recruiting or about to start. 112 of them are mainly about Post-Dural Puncture Headache (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Status

Completed
64
Recruiting
15
Status unknown
12
Not yet recruiting
10
Withdrawn
8
Terminated
7

Phase

Phase 4
15
Phase 2
10
Phase 3
9
Early Phase 1
2
Phase 1
1

Where

Egypt
31
Turkey
21
United States
16
France
8
Canada
5
Israel
4

Who runs them

Tanta University (5) · Ain Shams University (5) · Zagazig University (5) · Assiut University (5) · Minia University (3) · University Hospital Bispebjerg and Frederiksberg (3) · Centre Hospitalier Universitaire de Saint Etienne (2) · Damanhour Teaching Hospital (2)

What is being tested here

Drugs under test in Post-Dural Puncture Headache studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Neostigmine216
Sumatriptan103
Theophylline103
Ondansetron102
Gabapentin102
Oxytocin101
Ketorolac101
Glycopyrrolate101
Lidocaine005
Aminophylline013

Drug classes tested here Cholinesterase inhibitors 2 open · Bronchodilators 1 open · Phosphodiesterase inhibitors 1 open · Antiemetics 1 open · Antimuscarinics 1 open

Coming up

2phase 3 studies under way
12studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 15 Post-Dural Puncture Headache studies recruiting now, 7 (47%) set no upper age limit and 8 (53%) stop at 75 or younger. 1 (7%) take children under 18. 9 (60%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 15
AgeWomenMen
101 (7%)1 (7%)
1813 (87%)4 (27%)
3015 (100%)6 (40%)
4014 (93%)6 (40%)
509 (60%)5 (33%)
657 (47%)4 (27%)
757 (47%)4 (27%)
857 (47%)4 (27%)

Across all 122 studies, recruiting or not: 65% stop at 75 or younger and 62% at 65; 9% take children; 59% are for women only and 0% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Post-Dural Puncture Headache studies take

Of 34 interventional studies with no phase under Post-Dural Puncture Headache, half reached primary completion within 9 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase9 mo4–32 · 34 studies—9 mo4–32 · 33 studies
Observational15 mo6–38 · 18 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 122. Browse all 122 → or search them.