Pruritus clinical trials
The registry lists 352 studies for Pruritus across more than 10 countries. 72 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-22.
Status
- Completed
- 208
- Recruiting
- 37
- Not yet recruiting
- 30
- Status unknown
- 28
- Terminated
- 23
- Withdrawn
- 11
Phase
- Phase 2
- 105
- Phase 3
- 43
- Phase 1
- 34
- Phase 4
- 32
- Early Phase 1
- 10
Where
- United States
- 116
- Germany
- 36
- China
- 34
- Canada
- 28
- France
- 28
- Poland
- 23
Who runs them
University Hospital, Brest (17) · Cara Therapeutics, Inc. (15) · Vyne Therapeutics Inc. (8) · GlaxoSmithKline (8) · Mirum Pharmaceuticals, Inc. (6) · University Hospital, Basel, Switzerland (6) · Incyte Corporation (6) · Johns Hopkins University (4)
Studies
Recruiting first, then most recently updated. Showing 50 of 352 — search for more.
- Efficacy and Safety of ATTO-1310 in the Treatment of Participants With Chronic Pruritus of Unknown OriginNot yet recruitingNCT07833306Phase 2
- Topical Minocycline for CARPNot yet recruitingNCT07462702Early Phase 1
- Cervical Traction to Reduce Gabaergic Medication Use for Neuropathic ItchRecruitingNCT06751056Not applicable1 country
- Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis BullosaRecruitingNCT07482787Phase 31 country
- Efficacy and Speed of Response of Lebrikizumab in High-Burden Prurigo Nodularis PatientsNot yet recruitingNCT07620561Phase 21 country
- A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque PsoriasisRecruitingNCT06979453Phase 316 countries
- Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe PruritusRecruitingNCT06593392Phase 27 countries
- Cardamom and Topical Roseomonas in Atopic DermatitisRecruitingNCT06096857Phase 21 country
- Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.RecruitingNCT07560618Phase 41 country
- Drug-induced Liver Injury: Itching StudyRecruitingNCT064466091 country
- High-power Laser Therapy for Notalgia Paresthetica.RecruitingNCT07356362Not applicable1 country
- Effect of Non-Invasive Vagus Nerve Stimulation in Burn PatientsEnrolling by invitationNCT07566871Not applicable1 country
- Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn PatientsEnrolling by invitationNCT07566923Not applicable1 country
- Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)RecruitingNCT05263206Phase 313 countries
- The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 21 country
- TriCalm Hydrogel® in the Treatment of Immunotherapy-Related PruritusRecruitingNCT06748404Phase 21 country
- Establishment of a Patient Library in Patients With Pruritus Sine MateriaRecruitingNCT056783091 country
- Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome or Progressive Familial Intrahepatic Cholestasis in the European Union (LEAP-EU)RecruitingNCT07290257Phase 48 countries
- A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.RecruitingNCT07219615Phase 210 countries
- Efficacy and Tolerance of THC 25: CBD 25 in Patients With Severe Pruritus: a Multicenter, Double-blind, Randomized, Placebo-controlled StudyNot yet recruitingNCT06435299Phase 21 country
- Using Digital Health Technology to Monitor Patients With Primary Biliary Cholangitis (PBC)Enrolling by invitationNCT076314421 country
- A Phase I Clinical Trial to Evaluate the Single Dose Ascending and Food Effects of PG-033 in Healthy AdultsRecruitingNCT07013097Phase 11 country
- A Study to Evaluate the Multiple Dose Ascending of PG-033 in Healthy Adult Participants.Not yet recruitingNCT07619183Phase 11 country
- The Effect of Intraoperative Esketamine Infusion on Pruritus in Elderly Surgical PatientsNot yet recruitingNCT07597486Not applicable1 country
- Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian PopulationRecruitingNCT056910361 country
- Methotrexate Versus Apremilast for Pruritus in PsoriasisNot yet recruitingNCT07432386Phase 41 country
- Tolerance and Efficacy Open-label Study With RV4421B, in Various Populations With Atopic Dermatitis for 12 WeeksRecruitingNCT07014007Not applicable1 country
- The Effect of a Single Intravenous Injection of Esketamine During Cesarean Section on Postoperative Pruritus in Patients With Intrahepatic Cholestasis of PregnancyNot yet recruitingNCT07560722Not applicable1 country
- Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin DisordersRecruitingNCT05649098Early Phase 11 country
- EFFICACY OF ROFLUMILAST IN THE TREATMENT OF FLEXURAL AND/OR GENITAL PSORIASIS: A RANDOMIZED CONTROLLED TRIAL.Not yet recruitingNCT07543640Phase 2
- Assessing the Efficacy and Safety of Photobiomodulation for the Treatment of PruritusNot yet recruitingNCT07450716Early Phase 11 country
- VR-PMR for Post-Burn SymptomsRecruitingNCT07317271Not applicable1 country
- Effect of Pulsed Electromagnetic Field on Pruritus in Burn ScarsNot yet recruitingNCT07443358Not applicable
- A New Model to Induce Itch and InflammationNot yet recruitingNCT07395882Not applicable1 country
- Maralixibat for Intrahepatic Cholestasis of PregnancyNot yet recruitingNCT07389031Phase 21 country
- The Efficacy of High-Power Laser Therapy in Meralgia ParestheticaRecruitingNCT07328360Not applicable1 country
- An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database AnalysisRecruitingNCT066273351 country
- Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control PopulationRecruitingNCT062596691 country
- The Effects of an App-based Acupressure on Alleviating Fatigue, Pruritus, and Sleep Quality Among Hemodialysis PatientsNot yet recruitingNCT07259369Not applicable1 country
- Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.Not yet recruitingNCT07187427Not applicable1 country
- Topical Cannabidiol Lotion for Pruritus Relief in SclerodermaRecruitingNCT07245238Phase 31 country
- A Study to Assess the Safety and Efficacy of LB-P8 in Patients With PSCRecruitingNCT06699121Phase 21 country
- Evaluation of the Effectiveness of a Mobile Application Developed for Hemodialysis Patients.Not yet recruitingNCT07211100Not applicable1 country
- Topographical Distribution of Itch and Pain ReceptorsRecruitingNCT07122973Not applicable1 country
- Novel Strategies for Reducing Burn Scar ItchRecruitingNCT06801626Phase 31 country
- Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory ClinicRecruitingNCT06226610Phase 21 country
- TH104 for the Treatment of Pruritus in Primary Biliary CholangitisNot yet recruitingNCT06733519Phase 2
- SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)RecruitingNCT070214951 country
- A Clinical Study to Assess the Safety and Effectiveness of Utixira Lotion and Utixira Tablet in Healthy Adult Human Subjects With Dry or Sensitive Skin Prone to Mild to Moderate Pruritus and UrticariaNot yet recruitingNCT06924840Not applicable
- Aprepitant in the Management of Immune Checkpoint Inhibitors Pruritus in Solid Cancer PatientsNot yet recruitingNCT06931119Phase 1