Drug
Baclofen clinical trials
Also written Lioresal and Kemstro.
- studies test it
- 76
- open now
- 3
- in phase 3
- 18
- first study started
- 1997
Keep track of what changes. Save the Baclofen studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
75 studies that test it; most in 2013 (8)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 2003 | 5 |
| 2004 | 2 |
| 2005 | 6 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 2 |
| 2009 | 4 |
| 2010 | 5 |
| 2011 | 1 |
| 2012 | 7 |
| 2013 | 8 |
| 2014 | 3 |
| 2015 | 3 |
| 2016 | 4 |
| 2017 | 3 |
| 2018 | 3 |
| 2020 | 2 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 2 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 9
- Phase 2
- 30
- Phase 3
- 18
- Phase 4
- 16
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 68
Tanta University (3) · VA Office of Research and Development (3) · University of Pennsylvania (3) · Children's Hospital Medical Center, Cincinnati (2) · Assistance Publique - Hôpitaux de Paris (2) · Imperial College London (2) · University of North Carolina, Chapel Hill (2) · Universitaire Ziekenhuizen KU Leuven (2)
Often tested with
Tested in the same studies.
Memantine (3) · Tizanidine (2) · Gabapentin (2) · Botulinum toxin type A (2) · Roflumilast (1) · Naltrexone (1) · Sorbitol (1) · Chlorzoxazone (1)
Studies
Open first, then newest update. How each study uses Baclofen is read from its arms, and is right about nine times in ten.
Testing it · 76
- Synaptic Mechanisms of Continuous Theta Burst Stimulation in DepressionRecruitingEarly Phase 1Mclean HospitalNCT07560878Written as Baclofen
- Baclofen for Improving Benzodiazepine Titration in Benzodiazepine DependenceRecruitingPhase 2/3Hospices Civils de LyonNCT05935553Written as Baclofen 30 mg
- Effect of Baclofen in Management of Patients With Gastroesophageal Reflux Disease SymptomsRecruitingPhase 2/3Adnan Imtiaj RahulNCT07063576Written as Baclofen 10mg
- Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICUCompletedPhase 3Nantes University HospitalNCT02723383Written as BACLOFEN
- Electrical Neuromodulation for Modifying Spinal Network Involved in SpasticityActive, not recruitingNot applicableUniversity of Mississippi Medical CenterNCT07792616Written as Baclofen
- Study of the Effects on Motor Recovery of Early Post-stroke Spasticity TreatmentCompletedPhase 4University Hospital, ToulouseNCT02462317Written as Baclofen
- Baclofen for Children With Rumination SyndromeCompletedPhase 3Nationwide Children's HospitalNCT05975684Written as Baclofen
- Buprenorphine Plus Baclofen to Increase Analgesia in Healthy VolunteersTerminatedPhase 2/3University of Alabama at BirminghamNCT04251819Written as Baclofen 5 mg
- Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug ChallengeActive, not recruitingPhase 2Children's Hospital Medical Center, CincinnatiNCT05418049Written as Baclofen
- Phone-based Safety Monitoring of Baclofen Prescriptions for Alcohol Use DisorderTerminatedPhase 4University Hospital, LilleNCT02596763Written as Baclofen
- Baclofen for the Treatment of Alcohol DrinkersCompletedPhase 2/3Assistance Publique - Hôpitaux de ParisNCT01604330Written as Baclofen
- Baclofen Versus Gabapentin in Preventing Postoperative Pain After Laparoscopic Sleeve GastrectomyActive, not recruitingPhase 3Tanta UniversityNCT05921604Written as Baclofen 10mg
- Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric SurgeryCompletedPhase 2/3Tanta UniversityNCT05516953Written as Baclofen Tablets
- Evaluating the Safety of Acute Baclofen in Methadone-maintained Individuals With Opiate Dependence.CompletedPhase 4Imperial College LondonNCT05161351Written as Baclofen
- Effects of Baclofen on Presynaptic Inhibition in HumansWithdrawnPhase 2University of AlbertaNCT04471714Written as Baclofen
- Baclofen as a Perioperative Analgesic AdjuvantTerminatedPhase 4University of Alabama at BirminghamNCT03720717Written as Baclofen 10mg
- Comparative Bioavailability Study of Baclofen 20 mg Tablets in Healthy Male Volunteers / Fasting StateCompletedPhase 1Mylan Pharmaceuticals IncNCT00647738Written as Baclofen
- Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A PatientsActive, not recruitingPhase 3Pharnext S.C.A.NCT04762758Written as (RS)-baclofen, naltrexone hydrochloride and D-sorbitol
- Pharmacokinetic and Bioequivalence Comparison of Baclofen and Chlorzoxazone Administered Individually or ConcurrentlyCompletedPhase 1University of Texas Southwestern Medical CenterNCT05257447Written as Baclofen 20 mg Tablet
- Neurophysiological and Acute Pharmacological Studies in FXS PatientsCompletedEarly Phase 1Children's Hospital Medical Center, CincinnatiNCT02998151Written as Baclofen
See all 76 studies that test Baclofen →
Given in every arm · 1 — Baclofen is usual care beside what is tested
As the comparator · 4 — what is tested is compared with Baclofen
- Efficacy of Baclofen Vs Naltrexon in Achieving & Maintaining Abstinence in Alcohol Dependence.Not yet recruitingNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT06175507Written as Baclofen
- Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic PatientsTerminatedNot applicableMansoura UniversityNCT04509336Written as Baclofen
- Efficacy Study of Arbaclofen to Treat Spasticity in Multiple SclerosisCompletedPhase 3RVL Pharmaceuticals, Inc.NCT01743651Written as baclofen
- Oral and IV Baclofen in Adult VolunteersCompletedPhase 1University of MinnesotaNCT01749319Written as Oral baclofen
Codes
What other systems call Baclofen · ClinicalTrials.gg INT007043
- MeSH (NLM) D001418BaclofenConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) H789N3FKE8BACLOFENConfirmed FDA, NLM, Wikidata
- RxNorm 1292Confirmed FDA, Wikidata
- Wikidata Q413717(RS)-baclofenConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C28858BaclofenOne source FDA
- DrugBank DB00181One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001418 | Baclofen | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | H789N3FKE8 | BACLOFEN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1292 | — | Confirmed FDA, Wikidata |
| Wikidata | Q413717 | (RS)-baclofen | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C28858 | Baclofen | One source FDA |
| DrugBank | DB00181 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.