Drug
Dextromethorphan clinical trials
Also written Nuedexta, Delsym, Dex and AVP-923-20.
- studies test it
- 91
- open now
- 10
- in phase 3
- 14
- first study started
- 1993
Keep track of what changes. Save the Dextromethorphan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
91 studies that test it; most in 2012 (9)
| Year | Studies |
|---|---|
| 1993 | 2 |
| 1996 | 1 |
| 1997 | 1 |
| 2002 | 1 |
| 2003 | 7 |
| 2004 | 2 |
| 2005 | 3 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 3 |
| 2011 | 2 |
| 2012 | 9 |
| 2013 | 9 |
| 2014 | 3 |
| 2015 | 3 |
| 2016 | 5 |
| 2017 | 1 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 3 |
| 2021 | 5 |
| 2022 | 4 |
| 2023 | 4 |
| 2024 | 2 |
| 2025 | 2 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 24
- Phase 2
- 32
- Phase 3
- 14
- Phase 4
- 18
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 22 · Other 69
National Cheng-Kung University Hospital (7) · Avanir Pharmaceuticals (5) · Pfizer (3) · University Hospital, Clermont-Ferrand (2) · Brigham and Women's Hospital (2) · All India Institute of Medical Sciences, Bhubaneswar (2) · University of Florida (2) · Johns Hopkins University (2)
Often tested with
Tested in the same studies.
Midazolam (7) · Caffeine (7) · Omeprazole (5) · Memantine (4) · Quinidine (3) · Warfarin (3) · Vitamin K 1 (3) · AVP-923-30 (2)
Studies
Open first, then newest update. How each study uses Dextromethorphan is read from its arms, and is right about nine times in ten.
Testing it · 91
- Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic SurgeryRecruitingNot applicableCatherin ZhangNCT07860203Written as DEX 0.2 μg/kg/h.
- Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe DepressionRecruitingPhase 2Prof. Dr. Frank BehrensNCT06967857Written as DEX IR tablets
- A Study of Psychedelics in Healthy Older Adults With Low Well-beingRecruitingPhase 1Jennifer MitchellNCT07386730Written as Dextromethorphan (DXM)
- Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive DisorderNot yet recruitingPhase 1/2Mclean HospitalNCT07593222Written as Dextromethophan
- Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail ApproachRecruitingEarly Phase 1Washington State UniversityNCT06693960Written as Drug cocktail
- Study of Dextromethorphan in OCD and Related DisordersRecruitingPhase 2Stanford UniversityNCT04899687Written as Dextromethorphan
- Nintedanib With or Without Dextromethorphan in Patients With Idiopathic Pulmonary Fibrosis (IPF)Not yet recruitingPhase 2First Affiliated Hospital of Wenzhou Medical UniversityNCT07583589Written as Nintedanib,Dextromethorphan
- Dextromethorphan for Treatment of Postoperative PainRecruitingNot applicableNathanael HeckmannNCT05278494Written as Dextromethorphan Hydrobromide
- Investigation of Psychedelic Effects in Psychoactive SubstancesRecruitingPhase 1Johns Hopkins UniversityNCT06772753Written as Dextromethorphan (DXM)
- DEX vs SEVO in Congenital Heart SurgeryNot yet recruitingPhase 4Cliniques universitaires Saint-Luc- Université Catholique de LouvainNCT05369949Written as DEX group
- Dextromethorphan Added on for Children With Chronic IrritabilityCompletedPhase 4Tri-Service General Hospital (TSGH)NCT05043805Written as Dextromethorphan
- A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy ParticipantsCompletedPhase 1AstraZenecaNCT07241065Written as Dextromethorphan
- Conscious Sedation for Transcatheter Aortic Valve ImplantationCompletedNot applicableUniversity of IoanninaNCT05462938Written as Continuous infusion of dexmedetomidine
- Study of NMDA Antagonists and Neuropathic PainCompletedPhase 2University Hospital, Clermont-FerrandNCT01602185Written as Dextromethorphan (drug used like antitussive)
- Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical TrialCompletedPhase 2Brigham and Women's HospitalNCT01435798Written as Dextromethorphan
- Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical TrialCompletedPhase 2Brigham and Women's HospitalNCT02218203Written as Dextromethorphan
- Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex NeuroplasticityActive, not recruitingEarly Phase 1University Health Network, TorontoNCT04923659Written as Dextromethorphan
- Dextromethorphan as an Augmentation Agent in Treatment-resistant SchizophreniaCompletedPhase 4All India Institute of Medical Sciences, BhubaneswarNCT05944510Written as Dextromethorphan
- Dexmedetomidine Versus Midazolam for Peribulbar BlockCompletedNot applicableSuez Canal UniversityNCT06784843Written as Dexmedetomidine as an adjuvant to local anesthesia for peribulbar block
- A Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe SubstratesActive, not recruitingPhase 1Allyx TherapeuticsNCT06632990Written as dextromethorphan
See all 91 studies that test Dextromethorphan →
Given in every arm · 15 — Dextromethorphan is usual care beside what is tested
- A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate CancerActive, not recruitingPhase 1Aragon Pharmaceuticals, Inc.NCT02592317Written as Drug Cocktail
- A Study of Imlunestrant (LY3484356) in Female Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT05444556Written as Dextromethorphan
- Effects of Isotretinoin on CYP2D6 ActivityCompletedPhase 4University of WashingtonNCT03076021Written as dextromethorphan
- A Study of Mirikizumab in Participants With Plaque PsoriasisCompletedPhase 1Eli Lilly and CompanyNCT03718884Written as Drug Cocktail
- DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and DextromethorphanCompletedPhase 1Drugs for Neglected DiseasesNCT05947604Written as Dextromethorphan
- Licorice Botanical Dietary Supplements - Metabolism and Safety in WomenCompletedPhase 1University of Illinois at ChicagoNCT03948243Written as Dextromethorphan 30mg
- Endobiotics for Phenotyping of Human Cytochrome P450 EnzymesCompletedNot applicableJules DesmeulesNCT04188028Written as Dextromethorphan 5 MG
- Effects of Repeated Doses of Foliglurax on Drug Metabolizing Enzymes in Healthy SubjectsCompletedPhase 1H. Lundbeck A/SNCT04275115Written as Drug Cocktail
- Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult SubjectsCompletedPhase 1Galera Therapeutics, Inc.NCT03792971Written as Dextromethorphan HBr
- A Study of Ixekizumab in Participants With Plaque PsoriasisCompletedPhase 1Eli Lilly and CompanyNCT02993471Written as Drug Cocktail
- UARK 2006-15: A Study of Tandem Transplants With or Without Bortezomib and ThalidomideTerminatedPhase 3University of ArkansasNCT00574080Written as Interim/Maintenance Dexamethasone
- An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple SclerosisCompletedPhase 3BiogenNCT01462318Written as Dextromethorphan
- Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee ArthroplastyStatus unknownPhase 4KAT General HospitalNCT02966249Written as Dexmetomidine intravenously
- Study of Cobimetinib in Participants With Solid TumorsCompletedPhase 1Genentech, Inc.NCT00467779Written as dextromethorphan
- Treatment of Acute SinusitisCompletedPhase 4Washington University School of MedicineNCT00377403Written as Dextromethorphan hydrobromide with guaifenesin
As the comparator · 4 — what is tested is compared with Dextromethorphan
- Psilocybin-facilitated Treatment for Chronic PainRecruitingEarly Phase 1University of Alabama at BirminghamNCT05068791Written as Dextromethorphan
- Periarticular Injection Versus Peripheral Nerve Block in Total Hip ArthroplastyCompletedPhase 2Yale UniversityNCT03977454Written as Dex
- Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)CompletedPhase 1Merck Sharp & Dohme LLCNCT00934466Written as Comparator: Dextromethorphan
- A Pharmacokinetic (PK) Study Of PF-00299804 And Dextromethorphan In Healthy VolunteersCompletedPhase 1PfizerNCT00999817Written as reference [dextromethorphan]
Codes
What other systems call Dextromethorphan · ClinicalTrials.gg INT007327
- MeSH (NLM) D003915DextromethorphanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7355X3ROTSDEXTROMETHORPHANConfirmed FDA, NLM, Wikidata
- Wikidata Q407781dextromethorphanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62022DextromethorphanConfirmed FDA, Wikidata
- DrugBank DB00514One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003915 | Dextromethorphan | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7355X3ROTS | DEXTROMETHORPHAN | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q407781 | dextromethorphan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62022 | Dextromethorphan | Confirmed FDA, Wikidata |
| DrugBank | DB00514 | — | One source Wikidata |
Also registered as dextromethorphan hydrobromide (UNII 9D2RTI9KYH · RxNorm 102490), dextromethorphan hydrochloride (UNII 351KFH969D · RxNorm 267251) and racemethorphan (UNII 8YB8F78WM1).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.