Dementia clinical trials
The registry lists 2,372 studies for Dementia across more than 10 countries. 574 are recruiting or about to start. 1,000 of them are mainly about Dementia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 11 narrower conditions too, such as Alzheimer Disease: 6,004 studies, 1,425 open.
ClinicalTrials.gov finds 6,702 studies for Dementia. How that becomes 2,371 here
This page counts the studies the registry files under Dementia, and those it files under no condition that list Dementiathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 6,702Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −3,565Filed under a narrower condition, counted on its own pageAlzheimer Disease 2,941 · Huntington Disease 263 · Lewy Body Disease 99 · Frontotemporal Dementia 96 · Dementia, Vascular 46 · AIDS Dementia Complex 38 · 5 more
- −104List Dementia as a condition, but the registry did not file them under itMost often written as “Mild Dementia” (20), “Delirium, Dementia, Amnestic, Cognitive Disorders” (8), and “Behavioral and Psychiatric Symptoms of Dementia” (6). The registry filed them under other conditions only, most often Cognitive Dysfunction (36) and Parkinson Disease (13).
- −662Match it another way194 name it in the title, 38 in a keyword, and 430 by a synonym or other text the search reads.
- 2,371The count on this page110 of them list Dementia in their own words; the registry filed them under no condition.
Get an email when these change. Save the Dementia studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
VA Office of Research and Development (32) · The Hong Kong Polytechnic University (32) · Johns Hopkins University (27) · Indiana University (23) · Chang Gung Memorial Hospital (23) · University of Washington (22) · University College, London (20) · The University of Hong Kong (20)
What is being tested here
Drugs under test in Dementia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Xanomeline | 3 | 3 | 3 |
| Trospium | 3 | 3 | 3 |
| Methylphenidate | 2 | 0 | 7 |
| Donanemab | 2 | 4 | 5 |
| Atorvastatin | 2 | 1 | 3 |
| Remternetug | 2 | 3 | 3 |
| ML-007C | 2 | 0 | 2 |
| Lemborexant | 2 | 0 | 2 |
| Levetiracetam | 1 | 2 | 4 |
| Sodium Benzoate | 1 | 0 | 3 |
Drug classes tested here Antimuscarinics 3 open · Statins 2 open · Tyrosine kinase inhibitors (TKIs) 1 open · NSAIDs 1 open · Cholinesterase inhibitors 54
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function · Phase 3 · JYAMS PET Research & Development Limited
- Nov 2026Clinical Trial on Agitation in Alzheimer's Dementia · IGC Pharma, LLC
- Nov 2026Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling · University Health Network, Toronto
- Nov 2026Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES) · Rendever, Inc.
- Nov 2026Impact of a Biophoton Therapy on Patients With Brain Disorders · First Institute of All Medicines
- Nov 2026Support in Sound: Music Therapy for People Living With Dementia and Companions in Rural Communities · Anglia Ruskin University
- Nov 2026Prescribing Trends and Associated Outcomes of Antiepileptic Drugs in US Nursing Homes Surrounding the COVID-19 Pandemic · Virginia Commonwealth University
- Nov 2026The BRAIN App (Phase 2 SBIR) · Hopeful Aging
- Nov 2026Robotic Technologies for APATHy in Dementia: a Randomised Controlled Trial (RAPHAel) · Giovanna Zamboni
- Nov 2026Mindfulness-based Movement Therapy for Persons With Dementia and Family Caregivers · Drexel University
Who these studies take
Of the 381 Dementia studies recruiting now, 242 (64%) set no upper age limit and 25 (7%) stop at 75 or younger. 16 (4%) take children under 18. 2 (1%) are for women only and 1 (<1%) for men only; 163 (43%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (4%) | 15 (4%) |
| 18 | 126 (33%) | 126 (33%) |
| 30 | 151 (40%) | 151 (40%) |
| 40 | 173 (45%) | 172 (45%) |
| 50 | 241 (63%) | 240 (63%) |
| 65 | 371 (97%) | 371 (97%) |
| 75 | 367 (96%) | 367 (96%) |
| 85 | 336 (88%) | 336 (88%) |
Across all 2,372 studies, recruiting or not: 5% stop at 75 or younger and 2% at 65; 9% take children; 1% are for women only and 1% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dementia studies take
Of 83 phase 2 interventional studies under Dementia, half reached primary completion within 38 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 25 mo11–42 · 37 studies | — | — |
| Phase 1/2 | 49 mo24–68 · 17 studies | — | — |
| Phase 2 | 38 mo23–61 · 83 studies | 26 mo17–39 · 41 studies | 59 mo38–78 · 42 studies |
| Phase 2/3 | 56 mo41–59 · 20 studies | — | — |
| Phase 3 | 41 mo30–60 · 34 studies | — | — |
| Phase 4 | 59 mo29–80 · 20 studies | — | — |
| Interventional, no phase | 25 mo11–43 · 901 studies | 17 mo11–35 · 46 studies | 25 mo11–44 · 855 studies |
| Observational | 67 mo29–188 · 293 studies | — | 74 mo32–202 · 271 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting7
- Technology-Based Intervention Pilot TestingNov 6, 2026NCT07146581
- Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot StudyNov 5, 2026NCT07313540
- Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced DevicesNov 3, 2026NCT07066137
- Loneliness as Risk Factor for DementiaOct 28, 2026NCT07211945
- Telemonitoring of Activities of Daily Living in Home Care Services of Older Adults With Cognitive DeficitsOct 22, 2026NCT06888713
Show 2 moreShow fewer
- Choose Myself (Before) Losing MyselfOct 22, 2026NCT07846566
- CommunityRx-Dementia + Peer Navigation (CRxDpeer)Oct 13, 2026NCT07346183
Results posted2
- A Study of JNJ-63733657 in Participants With Early Alzheimer's DiseaseNov 5, 2026NCT04619420
- Home-based tDCS in Frontotemporal Dementia or Alzheimer's DiseaseOct 21, 2026NCT05978804
Stopped1
- The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With DementiaTerminatedNov 10, 2026NCT02415062
Newly registered20
- Cardiovascular And Dementia Risk in diabeTes: the Role of Nox2- Related Oxidative Stress.Nov 10, 2026NCT07928453
- The Effectiveness of Comic-based Learning Materials on Nursing Students' Knowledge, Attitudes, and Confidence in Dementia CareNov 6, 2026NCT07922109
- Music Listening for Chronic Pain in Adults With Early-Stage DementiaNov 5, 2026NCT07918534
- Prospective Research on Identification of Dementia in Early Stages (P.R.I.D.E)Nov 5, 2026NCT07918638
- China HEalthy Aging and Dementia Study (HEAD)Nov 3, 2026NCT07912710
Show 15 moreShow fewer
- Feasibility of Community Occupational Therapy for Dementia (COT-D)Oct 30, 2026NCT07905872
- Effects of Doll Therapy on Apathy and Activities of Daily Living Initiation Deficits in Older Adults With DementiaOct 30, 2026NCT07907042
- Network-based tDCS for ApathyOct 28, 2026NCT07900191
- Virtual Reality to Advance Dementia Care and Quality of LifeOct 26, 2026NCT07893678
- Fuzhou Aging Brain Health InitiativeOct 23, 2026NCT07891429
- The Effects of an Empower_ICE-Fit Program in PLwD Living at HomeOct 22, 2026NCT07889635
- Inpatient Hospice Transitions ChecklistOct 22, 2026NCT07889830
- Human-LLM Conversations as a Digital Signature of Cognitive Performance in AdultsOct 22, 2026NCT07890207
- Shedding Light on Dementia With Lewy Bodies: a Multimodal 'Bright Light Treatment' to Modulate Brain FunctionsOct 20, 2026NCT07882251
- SmartEnLite for Nursing Home Residents With DementiaOct 20, 2026NCT07883291
- EXercise-induced PhysioLogical Adaptations In Neurological DisordersOct 20, 2026NCT07883720
- Clinical Cohort of Memory DisordersOct 19, 2026NCT07880275
- A Prospective Cohort Study of Multimodal Biomarkers and Progression From Mild Cognitive Impairment to DementiaOct 15, 2026NCT07876570
- Functionalized Point of Care and 3D Printed Dental Aligners as Devices for Early Detection of Neurodegenerative DiseasesOct 13, 2026NCT07870070
- HomeCare Medication Management for People With DementiaOct 13, 2026NCT07872072
Studies
Recruiting first, then most recently updated. Showing 50 of 2,372. Browse all 2,372 → or search them.
- Cardiovascular And Dementia Risk in diabeTes: the Role of Nox2- Related Oxidative Stress.RecruitingNCT079284531 country
- Tennessee Alzheimer's ProjectRecruitingNCT053721721 country
- Feasibility of Community Occupational Therapy for Dementia (COT-D)Not yet recruitingNCT07905872Not applicable1 country
- Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for PreventionNot yet recruitingNCT07612800Not applicable1 country
- Technology-Based Intervention Pilot TestingRecruitingNCT07146581Not applicable1 country
- Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease DementiaRecruitingNCT07284472Phase 2/39 countries
- The Effectiveness of Comic-based Learning Materials on Nursing Students' Knowledge, Attitudes, and Confidence in Dementia CareNot yet recruitingNCT07922109Not applicable
- HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric SymptomsRecruitingNCT06930560Not applicable1 country
- Acupressure as Long-term Intervention to Slow the Progression of Early/Mild Alzheimer's DiseaseNot yet recruitingNCT07779863Not applicable1 country
- InRAD Observational StudyRecruitingNCT0721370017 countries
- In-depth Analysis of Cholesterol Metabolism and Related Biomarkers in the Pathogenesis and Progression of the Disease in Neurodegenerative DementiasRecruitingNCT072074861 country
- Telehealth-Adapted Compensatory Training and Intervention for CognitionRecruitingNCT07366346Not applicable1 country
- Feasibility of A Smartphone Application Intervention in Community Settings: A Pretest-Posttest Pilot StudyRecruitingNCT07313540Not applicable1 country
- Prospective Research on Identification of Dementia in Early Stages (P.R.I.D.E)Not yet recruitingNCT07918638
- Music Listening for Chronic Pain in Adults With Early-Stage DementiaNot yet recruitingNCT07918534Not applicable
- Prediction and Prevention of Postoperative Mortality and MorbidityNot yet recruitingNCT06042413Not applicable1 country
- A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related DecisionsRecruitingNCT07370311Not applicable1 country
- A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social EngagementNot yet recruitingNCT07773493Not applicable1 country
- A Study of LY3439539 in Participants With Alzheimer's DiseaseRecruitingNCT07598370Phase 14 countries
- China HEalthy Aging and Dementia Study (HEAD)RecruitingNCT079127101 country
- Prescribing Trends and Associated Outcomes of Antiepileptic Drugs in US Nursing Homes Surrounding the COVID-19 PandemicEnrolling by invitationNCT060952841 country
- A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's DementiaRecruitingNCT06651567Phase 28 countries
- Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced DevicesRecruitingNCT07066137Not applicable1 country
- The Existential Cognitive Intervention to Enhance Positive Aspect of Caregiving (EXCITE-PAC) in a Dementia ContextNot yet recruitingNCT07396298Not applicable1 country
- Effects of Doll Therapy on Apathy and Activities of Daily Living Initiation Deficits in Older Adults With DementiaRecruitingNCT07907042Not applicable1 country
- Intranasal Oxytocin Intervention for Caregivers to Persons With DementiaRecruitingNCT06364228Phase 21 country
- PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 11 country
- Inpatient Hospice Transitions ChecklistNot yet recruitingNCT07889830Not applicable1 country
- Buddy-Up Dyadic Physical Activity Program for Persons With Dementia and Family CaregiversRecruitingNCT06584110Not applicable1 country
- The Effectiveness of a Caregiver-Based Multicomponent Intervention to Prevent Pressure Ulcers in Home-Cared-For Individuals With DementiaNot yet recruitingNCT07843888Not applicable
- Tau PET Outcomes With Anti-amyloid ImmunotherapiesEnrolling by invitationNCT06723015Phase 21 country
- A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's DiseaseRecruitingNCT06297590Phase 13 countries
- Genetic Characterization of Movement Disorders and DementiasRecruitingNCT020142461 country
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).RecruitingNCT07602582Phase 33 countries
- Loneliness as Risk Factor for DementiaRecruitingNCT072119451 country
- Negotiation Training for Family Caregivers of People With Alzheimer's DiseaseNot yet recruitingNCT07859540Not applicable1 country
- Network-based tDCS for ApathyNot yet recruitingNCT07900191Not applicable
- Combating Alzheimer's Through Sleep and ExerciseRecruitingNCT04855630Not applicable1 country
- The WeACT Program for Family Caregivers of People Living With DementiaRecruitingNCT07342569Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseRecruitingNCT06976216Phase 319 countries
- Speech and Language Interventions for Italian People With PPARecruitingNCT067399671 country
- Virtual Reality to Advance Dementia Care and Quality of LifeNot yet recruitingNCT07893678Not applicable1 country
- Alzheimer's Tau Platform: Master ProtocolRecruitingNCT06957418Phase 21 country
- A Study Of Phototherapy In Patients With Dementia To Improve BPSDNot yet recruitingNCT07488195Not applicable1 country
- A Hybrid Effectiveness-Implementation and Cost-Utility Evaluation of a Support Programme for Informal Carers of People With Dementia in Primary Care (EsCuidar2)Not yet recruitingNCT07861789Not applicable1 country
- Fuzhou Aging Brain Health InitiativeRecruitingNCT078914291 country
- The Effects of an Empower_ICE-Fit Program in PLwD Living at HomeNot yet recruitingNCT07889635Not applicable1 country
- Human-LLM Conversations as a Digital Signature of Cognitive Performance in AdultsNot yet recruitingNCT07890207
- Choose Myself (Before) Losing MyselfRecruitingNCT07846566Not applicable1 country
- Telemonitoring of Activities of Daily Living in Home Care Services of Older Adults With Cognitive DeficitsRecruitingNCT06888713Not applicable1 country