Drug
Lithium clinical trials
- studies test it
- 73
- open now
- 3
- in phase 3
- 14
- first study started
- 1994
Keep track of what changes. Save the Lithium studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
- LI
- 1
Studies by the year they started
73 studies that test it; most in 2009 (7)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1997 | 1 |
| 2001 | 4 |
| 2002 | 2 |
| 2003 | 4 |
| 2004 | 4 |
| 2005 | 4 |
| 2006 | 2 |
| 2007 | 4 |
| 2008 | 2 |
| 2009 | 7 |
| 2010 | 7 |
| 2011 | 7 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 2 |
| 2019 | 2 |
| 2022 | 3 |
| 2023 | 2 |
| 2024 | 3 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 11
- Phase 2
- 14
- Phase 3
- 14
- Phase 4
- 26
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 13 · Other 60
AstraZeneca (6) · State University of New York at Buffalo (4) · Roxane Laboratories (4) · New York State Psychiatric Institute (3) · University of Sao Paulo (3) · Federal University of Rio Grande do Sul (2) · Shanghai Mental Health Center (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2)
Often tested with
Tested in the same studies.
Valproic Acid (14) · Quetiapine (10) · Lamotrigine (6) · Sertraline (4) · Carbamazepine (3) · Fluoxetine (3) · Escitalopram (3) · Venlafaxine (3)
Studies
Open first, then newest update. How each study uses Lithium is read from its arms, and is right about nine times in ten.
Testing it · 73
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment FailureRecruitingPhase 3Dr. Inge WinterNCT05603104Written as Lithium
- Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)RecruitingPhase 4Aalborg University HospitalNCT05913947Written as Lithium
- Lithium Treatment to Prevent Cognitive Impairment After Brain RadiotherapyRecruitingPhase 2Region StockholmNCT06051240Written as Lithium
- Repurposing Lithium for Parkinson's Disease: a RCTActive, not recruitingPhase 1/2State University of New York at BuffaloNCT06339034Written as Lithium
- Preventing Relapse After Successful Electroconvulsive Therapy for DepressionCompletedNot applicableUniversiteit AntwerpenNCT06751875Written as Lithium
- A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy ParticipantsCompletedPhase 1Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT06729970Written as Lithium
- Dose Escalation Study of Lithium With Oxaliplatin and Capecitabine in Advanced Oesophago-Gastric or Colorectal CancerTerminatedPhase 1Cancer Trials IrelandNCT03153280Written as Lithium
- Effect of Lithium Therapy on Long COVID SymptomsCompletedPhase 2State University of New York at BuffaloNCT05618587Written as Lithium
- Lithium Long COVID Dose-finding StudyCompletedPhase 1State University of New York at BuffaloNCT06108297Written as Lithium
- The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed PatientsCompletedPhase 1/2University of California, IrvineNCT00581009Written as sertraline, lithium
- Lithium Versus Paroxetine in Major DepressionWithdrawnPhase 4Nova Scotia Health AuthorityNCT01416220Written as Lithium
- A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal DegenerationCompletedPhase 1/2WestatNCT00703677Written as Lithium
- Treatment of Psychosis and Agitation in Alzheimer's DiseaseCompletedPhase 2New York State Psychiatric InstituteNCT02129348Written as Lithium
- Lithium for Suicidal Behavior in Mood DisordersTerminatedPhase 2/3VA Office of Research and DevelopmentNCT01928446Written as Lithium
- Lithium Versus Divalproex for Treating Pediatric Bipolar DisorderCompletedPhase 3Children's Hospital Medical Center, CincinnatiNCT00221429Written as Lithium
- Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease.CompletedPhase 1State University of New York at BuffaloNCT04273932Written as Lithium
- Electroconvulsive Therapy and Concomitant Lithium in Depressive Disorder: A Pilot StudyActive, not recruitingEarly Phase 1Melbourne HealthNCT05923476Written as Lithium
- Trial of Ketamine and Lithium Therapy in Bipolar DepressionWithdrawnPhase 2Yale UniversityNCT01768767Written as Ketamine/Lithium
- Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral CavityCompletedPhase 3CEL-SCI CorporationNCT01265849Written as LI
- PET and MRI Brain Imaging of Bipolar DisorderCompletedNot applicableStony Brook UniversityNCT01880957Written as Lithium
See all 73 studies that test Lithium →
Given in every arm · 13 — Lithium is usual care beside what is tested
- A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)RecruitingPhase 3Bristol-Myers SquibbNCT06929273Written as Lithium
- The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingPhase 3Dr. Inge WinterNCT05973786Written as Lithium
- Comparison of Combination Olanzapine+Lithium or Chlorpromazine+Lithium in Treatment of First Manic Episode With Psychotic FeaturesCompletedPhase 4Melbourne HealthNCT00202293Written as Lithium
- Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse DisorderCompletedPhase 3University Hospitals Cleveland Medical CenterNCT00194129Written as Lithium
- Algorithm Guided Treatment Strategies for Bipolar DepressionStatus unknownPhase 4Shanghai Mental Health CenterNCT01938859Written as Lithium
- Combination Therapy for the Treatment of Bipolar DisordersTerminatedPhase 3University Hospitals Cleveland Medical CenterNCT00063362Written as Lithium
- Atypical Antipsychotics for Continuation and Maintenance Treatment After an Acute Manic EpisodeCompletedPhase 3University of British ColumbiaNCT01977300Written as Lithium
- Combination Therapy in Dual Diagnosis Bipolar Rapid CyclingCompletedPhase 3University Hospitals Cleveland Medical CenterNCT00221975Written as Lithium
- Study to Evaluate the Efficacy and Safety of Aripiprazole Administered With Lithium or Valproate Over 12 Weeks in the Treatment of Mania in Bipolar I DisorderCompletedPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT00665366Written as Lithium
- Optimizing Electroconvulsive Therapy for DepressionCompletedPhase 4New York State Psychiatric InstituteNCT00045916Written as Lithium
- Interpersonal Psychotherapy for Treatment Resistant DepressionStatus unknownNot applicableHospital de Clinicas de Porto AlegreNCT01896349Written as Lithium
- Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of DepressionCompletedPhase 4Örebro County CouncilNCT00627887Written as Lithium
- Efficacy and Safety of Olanzapine in the Extended Treatment for Manic or Mixed Episode of Bipolar I DisorderCompletedPhase 3Eli Lilly and CompanyNCT00266630Written as lithium
As the comparator · 6 — what is tested is compared with Lithium
- Lithium Versus Quetiapine in Treatment Resistant DepressionStatus unknownPhase 4King's College LondonNCT03004521Written as Lithium
- Olanzapine Versus Lithium in the Treatment of Acute Depression in Patients With Bipolar II or Bipolar Not Otherwise Specified(OL Study)CompletedPhase 4Tadashi HasegawaNCT02287259Written as lithium
- Prolonging Remission in Depressed Elderly (PRIDE)CompletedPhase 4Icahn School of Medicine at Mount SinaiNCT01028508Written as lithium and Venlafaxine
- Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic RegulationCompletedPhase 4University of Alabama at BirminghamNCT01134731Written as lithium
- Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder PatientsTerminatedPhase 4Ministry of Health & Welfare, KoreaNCT00926835Written as Paroxetine+Lithium
- A Comparison of the Effectiveness of Seroquel XR and Seroquel XR Plus Lithium in Patients With Acute Bipolar Mania: An Open-label, Randomized, Parallel Groups, Rater-blinded, 4 Week, Multicenter, Comparative,StudyTerminatedPhase 4AstraZenecaNCT01254721Written as lithium
Codes
What other systems call Lithium · ClinicalTrials.gg INT007744
- MeSH (NLM) D008094LithiumConfirmed NLM, Wikidata
- UNII (FDA) 9FN79X2M3FLITHIUMConfirmed FDA, NLM, Wikidata
- RxNorm 6448Confirmed FDA, Wikidata
- Wikidata Q126603930LithiumConfirmed FDA, NLM, Wikidata
- Wikidata Q568lithiumConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C95186LithiumConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008094 | Lithium | Confirmed NLM, Wikidata |
| UNII (FDA) | 9FN79X2M3F | LITHIUM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6448 | — | Confirmed FDA, Wikidata |
| Wikidata | Q126603930 | Lithium | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q568 | lithium | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C95186 | Lithium | Confirmed FDA, Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.