Bradycardia clinical trials
The registry lists 317 studies for Bradycardia across more than 10 countries. 71 are recruiting or about to start. 197 of them are mainly about Bradycardia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Medtronic Cardiac Rhythm and Heart Failure (29) · Abbott Medical Devices (28) · Boston Scientific Corporation (15) · Medtronic (9) · MicroPort CRM (9) · Biotronik SE & Co. KG (8) · Sahiwal medical college sahiwal (5) · BackBeat Medical Inc (5)
What is being tested here
Drugs under test in Bradycardia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 3 | 2 | 6 |
| Ropivacaine | 1 | 2 | 2 |
| Dexamethasone | 1 | 2 | 2 |
| Propofol | 1 | 0 | 1 |
| Atropine | 0 | 0 | 8 |
| Glycopyrrolate | 0 | 0 | 3 |
| Sugammadex | 0 | 0 | 2 |
| Ivabradine | 0 | 0 | 2 |
| Levobupivacaine | 0 | 0 | 1 |
| Ondansetron | 0 | 0 | 1 |
Drug classes tested here Local anesthetics 1 open · Antimuscarinics 10
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled Trial · Yonsei University
- Nov 2026Dexmedetomidine and Propofol for Sedation in Cataract Surgery. · Saint-Joseph University
- Dec 2026His Bundle Pacing in Bradycardia and Heart Failure · Yong-Mei Cha
- Dec 2026The Leadless AV Versus DDD Pacing Study · Insel Gruppe AG, University Hospital Bern
- Dec 2026Evaluation of the Factors Associated With BRADYcardia Following Pulmonary Vein Isolation Using Pulsed Field Ablation · Wroclaw Medical University
- Jan 2027Merlin Expanded ECG NSR · Abbott Medical Devices
- Jan 2027Novel Setup Algorithm for Cardiac Neuromodulation Therapy · BackBeat Medical Inc
- Jan 2027Safety and Performances of the LINEA Cardiac Pacing Lead Optimized for the Implantation in Interventricular Septum · MicroPort CRM
- Mar 2027ALPs Single ChambEr New Device Study · Cairdac SA
- Mar 2027ALPs Single ChambEr New Device · Cairdac SA
Who these studies take
Of the 51 Bradycardia studies recruiting now, 34 (67%) set no upper age limit and 9 (18%) stop at 75 or younger. 4 (8%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 4 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (4%) | 2 (4%) |
| 18 | 44 (86%) | 43 (84%) |
| 30 | 48 (94%) | 47 (92%) |
| 40 | 48 (94%) | 47 (92%) |
| 50 | 48 (94%) | 47 (92%) |
| 65 | 46 (90%) | 46 (90%) |
| 75 | 42 (82%) | 42 (82%) |
| 85 | 40 (78%) | 40 (78%) |
Across all 317 studies, recruiting or not: 19% stop at 75 or younger and 16% at 65; 23% take children; 3% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bradycardia studies take
Of 83 interventional studies with no phase under Bradycardia, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 21 mo12–38 · 83 studies | 18 mo9–32 · 36 studies | 28 mo12–59 · 47 studies |
| Observational | 42 mo18–96 · 73 studies | 34 mo17–79 · 35 studies | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Transjugular Approach for Implantation of Active Fixation Leadless PacemakersNov 10, 2026NCT07802119
Newly registered7
- Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart FailureNov 10, 2026NCT07929467
- Intrathecal Dexmedetomidine 5 mcg Versus 10 mcg With Bupivacaine for Infra-umbilical SurgeryNov 10, 2026NCT07929818
- nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 WeeksNov 6, 2026NCT07923604
- Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean SectionOct 20, 2026NCT07883772
- Belgo-Luxembourg Leadless PM RegistryOct 19, 2026NCT07879716
Show 2 moreShow fewer
- Merlin Expanded ECG NSROct 16, 2026NCT07877805
- Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in JapanOct 13, 2026NCT07870837
Studies
Recruiting first, then most recently updated. Showing 50 of 317. Browse all 317 → or search them.
- Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart FailureNot yet recruitingNCT07929467Not applicable1 country
- nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 WeeksNot yet recruitingNCT07923604Not applicable1 country
- Transjugular Approach for Implantation of Active Fixation Leadless PacemakersRecruitingNCT07802119Not applicable1 country
- Leadless Pacemaker Registry: Outcomes and Follow-up From the University Hospital of St. PöltenRecruitingNCT072461351 country
- Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy ProductsRecruitingNCT0027118035 countries
- BIO|STREAM.CSP StudyRecruitingNCT0739300913 countries
- SPIKE FLOW Endocardial Lead Safety and Performance StudyRecruitingNCT07820072Not applicable1 country
- Aveir AR Coverage With Evidence Development (CED) StudyRecruitingNCT061007701 country
- Belgo-Luxembourg Leadless PM RegistryNot yet recruitingNCT07879716Not applicable2 countries
- Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in JapanNot yet recruitingNCT07870837Not applicable1 country
- LEAP 2 Chronic EFSRecruitingNCT07287423Not applicable1 country
- BIOTRONIK Investigation of the LivIQ Leadless Pacemaker SystemRecruitingNCT07118358Not applicable8 countries
- Merlin Expanded ECG NSRNot yet recruitingNCT07877805
- Elevated Midline Positioning During Diaper Change in Preterm InfantsNot yet recruitingNCT07865897Not applicable
- PACE Cognition Proof-of-Concept StudyNot yet recruitingNCT07769424Not applicable1 country
- Novel Setup Algorithm for Cardiac Neuromodulation TherapyRecruitingNCT05719454Not applicable3 countries
- Application to Predict Neonatal Apnea With BradycardiaRecruitingNCT06852053Not applicable1 country
- Left Bundle Branch Area Pacing (LBBAP) PMCF StudyRecruitingNCT07217392Not applicable9 countries
- Safety and Performances of the LINEA Cardiac Pacing Lead Optimized for the Implantation in Interventricular SeptumRecruitingNCT07342608Not applicable5 countries
- Impact of Allometric Pacing Rate on Ventricular Diastolic Function and Cerebral Blood Flow in Hypertensive Patients With Sinus Node DysfunctionRecruitingNCT07589452Not applicable1 country
- Cardiac Arrhythmias in Pediatric Emergency DepartmentNot yet recruitingNCT07826273
- Evaluation of the Factors Associated With BRADYcardia Following Pulmonary Vein Isolation Using Pulsed Field AblationRecruitingNCT078093471 country
- Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal CaptureNot yet recruitingNCT07804394Not applicable
- Chronic Evaluation of Novel Pacemaker SystemRecruitingNCT06056817Not applicable1 country
- Conduction System Pacing Display Research System for SmartSync Pacing System AnalyzerRecruitingNCT077339601 country
- "Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment" (PROTECT-HF)RecruitingNCT05815745Not applicable3 countries
- HeartBeam ECG RegistryRecruitingNCT075012991 country
- Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for BradyarrhythmiasRecruitingNCT07671898Not applicable1 country
- Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657715Not applicable1 country
- Aveir DR Real-World Evidence Post-Approval StudyRecruitingNCT059350071 country
- Permanent Conduction System Pacing Versus Atrioventricular Management for Patients With Wide QRS and Patent AV ConductionRecruitingNCT07585799Not applicable1 country
- Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)RecruitingNCT066413623 countries
- Impact of Optimized Pacing Strategies on Clinical and Hemodynamic Outcomes in Heart Failure Patients With PacemakerRecruitingNCT07563153Not applicable1 country
- Dexmedetomidine and Propofol for Sedation in Cataract Surgery.RecruitingNCT07556133Not applicable1 country
- ALPs Single ChambEr New Device StudyNot yet recruitingNCT07469579Not applicable
- ALPs Single ChambEr New DeviceNot yet recruitingNCT07461935Not applicable
- Pacemaker-based Long-term Monitoring of Sleep ApneaRecruitingNCT051277201 country
- LLL vs. SDL for LBBP: A Non-inferiority RCTNot yet recruitingNCT07378124Not applicable1 country
- Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb SurgeryRecruitingNCT07221682Phase 2/31 country
- PReventive Effect Of Left Bundle Branch Area Pacing Versus righT vEntricular paCing on All Cause deaTh, Heart Failure Progression, and Ventricular dysSYNChrony in Patients With Substantial Ventricular Pacing (PROTECT-SYNC): Multicenter Prospective Randomized Controlled TrialRecruitingNCT05585411Not applicable1 country
- His Bundle Pacing in Bradycardia and Heart FailureRecruitingNCT030082911 country
- Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb SurgeriesRecruitingNCT07290595Phase 2/31 country
- The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm InfantsRecruitingNCT05298748Not applicable1 country
- Evaluation of a Single-lead ECG Patch-based Telemetry System for In-hospital MonitoringNot yet recruitingNCT07260721Not applicable1 country
- Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture SurgeryRecruitingNCT06568770Phase 2/31 country
- Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)RecruitingNCT040750849 countries
- The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated PatientsRecruitingNCT06503016Phase 31 country
- AVEIR™ Leadless Pacemaker (LP) United Kingdom (UK) RegistryRecruitingNCT068544841 country
- National Registry of Cardioneuroablation in Recurrent Reflex SyncopeRecruitingNCT061597641 country
- Clinical Safety and Efficacy Testing of a Medical Device Kardi Ai, an ECG Telemetry Monitoring SystemRecruitingNCT07018648Not applicable1 country