Postpartum Hemorrhage clinical trials
The registry lists 469 studies for Postpartum Hemorrhage across more than 10 countries. 76 are recruiting or about to start. 419 of them are mainly about Postpartum Hemorrhage (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Who runs them
Samuel Lunenfeld Research Institute, Mount Sinai Hospital (34) · Gynuity Health Projects (23) · Cairo University (20) · Assiut University (15) · Aswan University Hospital (12) · Stanford University (7) · Assistance Publique - Hôpitaux de Paris (6) · Ain Shams University (6)
What is being tested here
Drugs under test in Postpartum Hemorrhage studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Prophylactic Amnioinfusion for Prevention of Postpartum Hemorrhage · Phase 3 · The University of Texas Health Science Center, Houston
- Jan 2027EVE TRIAL , ALMA SYSTAM · Phase 3 · ResQ Medical Ltd
- Jan 2027Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage · Phase 3 · Stony Brook University
- Jun 2027TRAnexamic Acid for Preventing Blood Loss Following a Cesarean Delivery in Women With Placenta pREVIA · Phase 3 · University Hospital, Bordeaux
- Sep 2027Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women at Higher Risk · Phase 3 · London School of Hygiene and Tropical Medicine
- Nov 2026Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section · Pak Emirates Military Hospital
- Nov 2026Web-Based Gamification in Postpartum Hemorrhage Management Education Among Midwifery Students · Mersin University
- Dec 2026Oxytocin Maintenance Infusion in Labouring Women Undergoing Cesarean Delivery: an Up-down Sequential Allocation Study · Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Dec 2026Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study · Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Dec 2026Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium · Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Who these studies take
Of the 42 Postpartum Hemorrhage studies recruiting now, 21 (50%) set no upper age limit and 21 (50%) stop at 75 or younger. 6 (14%) take children under 18. 39 (93%) are for women only and 1 (2%) for men only; 21 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (12%) | 1 (2%) |
| 18 | 38 (90%) | 2 (5%) |
| 30 | 41 (98%) | 3 (7%) |
| 40 | 40 (95%) | 3 (7%) |
| 50 | 30 (71%) | 3 (7%) |
| 65 | 21 (50%) | 3 (7%) |
| 75 | 20 (48%) | 3 (7%) |
| 85 | 20 (48%) | 3 (7%) |
Across all 469 studies, recruiting or not: 58% stop at 75 or younger and 57% at 65; 25% take children; 92% are for women only and <1% for men only; 48% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Postpartum Hemorrhage studies take
Of 28 phase 4 interventional studies under Postpartum Hemorrhage, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 18 mo9–38 · 20 studies | — | — |
| Phase 4 | 12 mo10–20 · 28 studies | — | 12 mo10–20 · 27 studies |
| Interventional, no phase | 16 mo7–26 · 119 studies | — | 16 mo7–26 · 112 studies |
| Observational | 21 mo9–38 · 42 studies | — | 30 mo10–39 · 38 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- U-CaVIT Versus Standard of Care for Prevention of Atonic Postpartum Hemorrhage After Cesarean Section in High-risk Women.TerminatedOct 16, 2026NCT07019623
Newly registered5
- Comparison of Effect of Two Different Doses of Intravenous Oxytocin on Patients Undergoing Elective Cesarean SectionNov 6, 2026NCT07922083
- The Effect of Using Virtual Simulation on Students' Knowledge and Skill Levels Regarding Postpartum Hemorrhage ManagementNov 3, 2026NCT07912021
- Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in WaterbirthOct 21, 2026NCT07884890
- Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum HemorrhageOct 21, 2026NCT07885072
- Tranexamic Acid for Reducing Blood Loss in High-Risk Cesarean DeliveryOct 13, 2026NCT07870499
Studies
Recruiting first, then most recently updated. Showing 50 of 469. Browse all 469 → or search them.
- HISTOACRYL® Used for Embolization of Thoracoabdominal Artery BleedingNot yet recruitingNCT077530051 country
- Comparison of Effect of Two Different Doses of Intravenous Oxytocin on Patients Undergoing Elective Cesarean SectionNot yet recruitingNCT07922083Not applicable
- Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women at Higher RiskRecruitingNCT05562609Phase 31 country
- Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in WaterbirthNot yet recruitingNCT078848901 country
- Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum HemorrhageRecruitingNCT078850721 country
- Prevention of Postpartum Hemorrhage With Tranexamic AcidRecruitingNCT05370820Phase 21 country
- Hemoglobin Testing in Pregnant PatientsRecruitingNCT059776861 country
- Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority TrialRecruitingNCT07636421Phase 41 country
- Effect of Simulation-Based Postpartum Hemorrhage Training on Team Performance in Senior Anesthesiology TeamsRecruitingNCT07519252Not applicable1 country
- Comparing Simulated Patients and Manikin Based Simulation in ObstetricsNot yet recruitingNCT07857551Not applicable1 country
- Efficacy of Balloon Tamponade in Post-partum Hemorrhage Within 24 Hours After DeliveryNot yet recruitingNCT078452401 country
- A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in IndiaRecruitingNCT07157423Phase 41 country
- Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal AnaesthesiaNot yet recruitingNCT07784478Not applicable1 country
- Oxytocin Pharmacokinetics and PharmacodynamicsRecruitingNCT05488457Phase 21 country
- Maternal Outcomes Following Manual Lysis of the Placenta.RecruitingNCT03626844Not applicable1 country
- Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR)Not yet recruitingNCT07688512Phase 4
- The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue MorbidityRecruitingNCT06494878Phase 37 countries
- A Pragmatic Randomized Controlled Trial to Predict Postpartum HemorrhageRecruitingNCT06513351Not applicable1 country
- Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal DeliveryRecruitingNCT07714902Not applicable1 country
- Web-Based Gamification in Postpartum Hemorrhage Management Education Among Midwifery StudentsNot yet recruitingNCT07688122Not applicable
- Topical Tranexamic Acid to Reduce Blood Loss During Cesarean DeliveryRecruitingNCT07362992Early Phase 11 country
- Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard CareRecruitingNCT06963047Not applicable1 country
- Immediate vs Delayed Postpartum Implanon-NXTNot yet recruitingNCT07626502
- Prediction of Platelet Function Using Viscoelastic Test (ROTEM® Sigma) in Obstetric Anesthesia.RecruitingNCT076163491 country
- Balloon Tamponade Versus Gauze Packing for Postpartum HemorrhageNot yet recruitingNCT07609589Not applicable
- Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine ToneNot yet recruitingNCT07606846Not applicable
- Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum HemorrhageRecruitingNCT07401524Phase 41 country
- SWIFT - SWIss Factor XIII Trial in PPHRecruitingNCT06481995Phase 41 country
- Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean SectionNot yet recruitingNCT07550413Phase 21 country
- Sublingual Oxytocin for the Prevention of Post-partum HemorrhageNot yet recruitingNCT06968481Phase 21 country
- THUMB: Multi-centre Cluster Trial for Caesarean Section HaemorrhageRecruitingNCT07005349Not applicable1 country
- PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)RecruitingNCT072634901 country
- Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro StudyRecruitingNCT06285396Not applicable1 country
- Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human MyometriumRecruitingNCT06285409Not applicable1 country
- Oxytocin Maintenance Infusion in Labouring Women Undergoing Cesarean Delivery: an Up-down Sequential Allocation StudyRecruitingNCT05290129Not applicable1 country
- Investigating the Efficacy of Tranexamic Acid as a Prophylactic Agent in Reducing Postpartum Hemorrhage Among Patients Undergoing Cesarean Section in SQUHNot yet recruitingNCT07474077Phase 3
- Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean DeliveryRecruitingNCT06333340Not applicable1 country
- Effect of Co-administration of Carbetocin and Calcium Chloride on Uterine Tone in Patients Undergoing Elective Cesarean DeliveryRecruitingNCT07187544Not applicable1 country
- EVE TRIAL , ALMA SYSTAMRecruitingNCT06646653Phase 32 countries
- Hemophilia A Research ProgramRecruitingNCT074145111 country
- Umbilical Cord Drainage to Prevent Postpartum HemorrhageRecruitingNCT07401160Not applicable1 country
- Carbetocin vs Misoprostol for Postpartum Hemorrhage PreventionNot yet recruitingNCT07353281Not applicable
- Prophylactic Regimen of Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative for Primary Prevention of Postpartum Hemorrhage in Intrapartum Cesarean Section Versus Intravenous Carbetocin AloneNot yet recruitingNCT07318467Not applicable
- Trends in the Administration of Tranexamic Acid for Postpartum HemorrhageRecruitingNCT072780371 country
- Von Willebrand Factor in Pregnancy (VIP) StudyRecruitingNCT041463761 country
- The Effect of Placental Cord Drainage on the Third Stage of Labor and the Amount of Postpartum BleedingRecruitingNCT07279545Not applicable1 country
- Temporary Aortic Compression With the Abdominal Tourniquet for Refractory Postpartum HemorrhageRecruitingNCT07034924Not applicable1 country
- The Effect of Gamification-Based Instructional Design DevelopedNot yet recruitingNCT07207590Not applicable1 country
- Detection of Bleeding Disorders Diagnosed After Vaginal Delivery Complicated by Severe Postpartum HemorrhageNot yet recruitingNCT069708601 country
- Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human MyometriumRecruitingNCT06930391Not applicable1 country