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Weight Loss clinical trials

The registry lists 1,815 studies for Weight Loss across more than 10 countries. 294 are recruiting or about to start. 298 of them are mainly about Weight Loss (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Cachexia too: 2,115 studies, 362 open.

ClinicalTrials.gov finds 3,503 studies for Weight Loss. How that becomes 1,814 here

This page counts the studies the registry files under Weight Loss, and those it files under no condition that list Weight Lossthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 3,503Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −272Filed under a narrower condition, counted on its own pageCachexia 272
  3. −22List Weight Loss as a condition, but the registry did not file them under itMost often written as “Weight Loss Maintenance” (3), “Weight Loss Trial” (3), and “Inadequate Initial Weight Loss” (2). The registry filed them under other conditions only, most often Obesity (12) and Overweight (5).
  4. −1,395Match it another way1,134 name it in the title, 93 in a keyword, and 168 by a synonym or other text the search reads.
  5. 1,814The count on this page11 of them list Weight Loss in their own words; the registry filed them under no condition.

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Status

Completed
1,184
Recruiting
196
Status unknown
139
Active, not recruiting
88
Not yet recruiting
84
Terminated
65

Phase

Phase 2
157
Phase 3
96
Phase 4
82
Phase 1
67
Early Phase 1
7

Where

United States
995
Canada
67
China
51
Germany
49
United Kingdom
49
Spain
47

Who runs them

The Miriam Hospital (29) · Wake Forest University Health Sciences (28) · University of Pittsburgh (22) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (22) · University of California, San Diego (21) · University of Alabama at Birmingham (21) · University of Colorado, Denver (20) · University of North Carolina, Chapel Hill (20)

What is being tested here

Drugs under test in Weight Loss studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Semaglutide15424
Tirzepatide9210
VK2735348
Metformin239
Phentermine207
Ponsegromab215
Berobenatide223
Mazdutide203
Efsubaglutide alfa202
Liraglutide1516

Drug classes tested here GLP-1 receptor agonists 24 open · Stimulants 2 open · Antipsychotics 1 open · SGLT2 inhibitors 9 · Antiemetics 3

Coming up

22phase 3 studies under way
125studies finish main data collection within a year8 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 196 Weight Loss studies recruiting now, 71 (36%) set no upper age limit and 108 (55%) stop at 75 or younger. 21 (11%) take children under 18. 11 (6%) are for women only and 4 (2%) for men only; 58 (30%) take healthy volunteers.

Recruiting studies that take each age, of 196
AgeWomenMen
109 (5%)7 (4%)
18147 (75%)142 (72%)
30168 (86%)162 (83%)
40172 (88%)166 (85%)
50171 (87%)164 (84%)
65149 (76%)142 (72%)
7599 (51%)93 (47%)
8580 (41%)74 (38%)

Across all 1,815 studies, recruiting or not: 64% stop at 75 or younger and 48% at 65; 8% take children; 13% are for women only and 3% for men only; 44% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Weight Loss studies take

Of 45 phase 4 interventional studies under Weight Loss, half reached primary completion within 29 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 115 mo8–25 · 24 studies——
Phase 232 mo11–56 · 44 studies——
Phase 324 mo14–28 · 23 studies——
Phase 429 mo19–46 · 45 studies—33 mo25–51 · 40 studies
Interventional, no phase24 mo11–43 · 729 studies10 mo6–21 · 59 studies25 mo13–45 · 670 studies
Observational32 mo16–99 · 92 studies—37 mo17–99 · 86 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting4

Results posted2

Stopped1

Newly registered17

Show 12 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,815. Browse all 1,815 → or search them.