Brain Neoplasms clinical trials
The registry lists 1,958 studies for Brain Neoplasms across more than 10 countries. 517 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 729
- Recruiting
- 397
- Terminated
- 224
- Status unknown
- 197
- Active, not recruiting
- 173
- Not yet recruiting
- 107
Phase
- Phase 2
- 594
- Phase 1
- 402
- Phase 3
- 118
- Early Phase 1
- 57
- Phase 4
- 34
Where
- United States
- 1,036
- China
- 188
- France
- 146
- Canada
- 139
- Germany
- 76
- Italy
- 72
Who runs them
National Cancer Institute (NCI) (80) · M.D. Anderson Cancer Center (77) · Memorial Sloan Kettering Cancer Center (40) · Duke University (30) · Mayo Clinic (26) · Case Comprehensive Cancer Center (23) · University Health Network, Toronto (22) · Sun Yat-sen University (21)
Studies
Recruiting first, then most recently updated. Showing 50 of 1,958 — search for more.
- C-SMART vs BE Well for Patients With Brain TumorsRecruitingNCT07224503Not applicable1 country
- Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT000605411 country
- Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain MetastasisRecruitingNCT06047379Phase 1/21 country
- Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent GlioblastomaRecruitingNCT07416188Phase 1/21 country
- RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)RecruitingNCT06389591Phase 11 country
- Extracellular Impact of Ultrasound-induced Blood-brain Barrier DisruptionRecruitingNCT05733312Not applicable1 country
- Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the BrainRecruitingNCT07470606Phase 21 country
- Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)RecruitingNCT07248228Phase 21 country
- Feasibility of 18F-Fluciclovine PET/CT to Identify Brain MetastasisRecruitingNCT06055790Early Phase 11 country
- Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent GlioblastomaRecruitingNCT04977375Phase 1/21 country
- REMIND Maintenance Radiotherapy for Newly Diagnosed GlioblastomaRecruitingNCT07831772Not applicable1 country
- A Phase 1 Study of SRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma.Not yet recruitingNCT07826949Phase 11 country
- A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain MetastasesRecruitingNCT05048212Phase 21 country
- Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)RecruitingNCT07053033Phase 21 country
- Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)RecruitingNCT07227610Phase 21 country
- PilotStudyAssessSafeActiveSurveillancApproachLocalThe Pa w/BrainMetsUndergoinCNSPenetratSystemicTheRecruitingNCT078270011 country
- Intraoperative Ultrasound for Brain Tumor Surgery Enhanced by AINot yet recruitingNCT07376304Phase 3
- SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain MetastasesRecruitingNCT04923542Phase 1/21 country
- Preoperative Embolization for Highly Vascular Brain TumorsNot yet recruitingNCT07823985Not applicable
- Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive MalignanciesRecruitingNCT05786924Phase 1/210 countries
- Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness MeasurementsNot yet recruitingNCT066303381 country
- Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIRecruitingNCT07326566Phase 21 country
- Effectiveness of a Visual Telerehabilitation Program on Visual Perception in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain TumourNot yet recruitingNCT07558395Not applicable7 countries
- A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)RecruitingNCT07492680Phase 213 countries
- Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed MedulloblastomaRecruitingNCT05535166Phase 21 country
- Development of MRF for Characterization of Brain Tumors After RadiotherapyRecruitingNCT06101069Not applicable1 country
- A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain MetastasesRecruitingNCT04511013Phase 21 country
- Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) TumorsRecruitingNCT07374692Not applicable1 country
- OBSERVE: A Pilot Study Of Omission Of Brain Metastasis Stereotactic Radiosurgery Following Resection With CNS-Active Systemic TherapyRecruitingNCT07655583Phase 11 country
- Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous SystemRecruitingNCT03270059Phase 21 country
- Frameless Stereotactic Radiosurgery for Intact Brain MetastasesRecruitingNCT02747303Phase 21 country
- Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients With Brain Lesions.RecruitingNCT06797661Not applicable1 country
- Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-OncologyRecruitingNCT049880091 country
- Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity TrainingRecruitingNCT07105358Not applicable1 country
- Home-based Vision Rehabilitation Guided by Brain ImagingRecruitingNCT07635329Not applicable1 country
- Asciminib With or Without Sildenafil for Brain TumorsNot yet recruitingNCT07039760Early Phase 11 country
- GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young AdultsRecruitingNCT07087002Phase 11 country
- Susceptibility-Weighted Imaging in Preoperative Grading of Cerebral GliomasNot yet recruitingNCT07813741
- MELanoma Brain Metastasis Treated With CYberknifeRecruitingNCT076912551 country
- IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)Not yet recruitingNCT06946680Phase 11 country
- Repotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain MetastasisRecruitingNCT06315010Phase 23 countries
- IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain MetastasesNot yet recruitingNCT07569263Phase 11 country
- Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain MetastasesRecruitingNCT04899908Phase 21 country
- The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological ComplicationsNot yet recruitingNCT07805876Not applicable1 country
- Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast CancerRecruitingNCT05386108Phase 1/210 countries
- A Phase 1/1b Study of IAM1363 in HER2 CancersRecruitingNCT06253871Phase 18 countries
- Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain MetastasesRecruitingNCT04033497Not applicable1 country
- FearLess in NeuroOncologyRecruitingNCT06989086Not applicable1 country
- A Study to Evaluate the Safety and Efficacy of Intracranial Venous Blood Sampling for Liquid Biopsy in the Diagnosis of Brain CancersRecruitingNCT074671091 country
- NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain TumorsRecruitingNCT07664176Phase 11 country