Brain Neoplasms clinical trials

The registry lists 2,440 studies for Brain Neoplasms across more than 10 countries. 540 are recruiting or about to start. 1,202 of them are mainly about Brain Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 9 narrower conditions too, such as Pituitary Neoplasms: 2,892 studies, 657 open.

ClinicalTrials.gov finds 4,497 studies for Brain Neoplasms. How that becomes 2,439 here

This page counts the studies the registry files under Brain Neoplasms, and those it files under no condition that list Brain Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

4,497Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
−386Filed under a narrower condition, counted on its own pagePituitary Neoplasms 174 · Diffuse Intrinsic Pontine Glioma 86 · Choroid Plexus Neoplasms 57 · Infratentorial Neoplasms 19 · Pinealoma 17 · Prolactinoma 15 · 3 more
−81List Brain Neoplasms as a condition, but the registry did not file them under itMost often written as “Brain Tumor Adult” (14), “Pediatric Brain Tumor” (10), and “Childhood Brain Tumor” (9). The registry filed them under other conditions only, most often Neoplasms (18) and Glioma (12).
−1,595Match it another way282 name it in the title, 30 in a keyword, and 1,283 by a synonym or other text the search reads.
2,435Counted here and found by its search64 of them list Brain Neoplasms in their own words; the registry filed them under no condition.
+4
Counted here, but its search does not find them
2,439The count on this page

Get an email when these change. Save the Brain Neoplasms studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies

See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed: 1,098
Recruiting: 423
Terminated: 285
Status unknown: 219
Active, not recruiting: 176
Withdrawn: 107

Phase

Phase 2: 798
Phase 1: 601
Phase 3: 153
Early Phase 1: 66
Phase 4: 36

Where

United States: 1,443
Canada: 180
China: 179
France: 172
Germany: 104
Italy: 95

Who runs them

National Cancer Institute (NCI) (136) · M.D. Anderson Cancer Center (87) · Duke University (66) · Memorial Sloan Kettering Cancer Center (51) · Case Comprehensive Cancer Center (29) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (28) · Mayo Clinic (28) · St. Jude Children's Research Hospital (25)

What is being tested here

Drugs under test in Brain Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Bevacizumab	6	6	66
Pembrolizumab	6	0	18
Ipilimumab	5	1	21
Capecitabine	5	0	10
Temozolomide	4	9	119
Nivolumab	4	3	23
Etoposide	3	3	24
Cyclophosphamide	3	1	12
Fluciclovine F-18	3	1	8
Levetiracetam	3	2	8

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 25 open · Immune checkpoint inhibitors 16 open · Antibody-drug conjugates (ADCs) 9 open · Alkylating agents 8 open · Antimetabolites 7 open

Coming up

44phase 3 studies under way

238studies finish main data collection within a year16 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Dec 2026International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma · Phase 3 · Universitätsklinikum Hamburg-Eppendorf
Dec 2026Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma · Phase 3 · Eastern Cooperative Oncology Group
Dec 2026A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients · Phase 3 · NaviFUS Corporation
Dec 2026Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer · Phase 3 · Chang Gung Memorial Hospital
Jan 2027Levetiracetam for Seizure Prevention After Brain Tumor Surgery · Phase 3 · Beijing Tiantan Hospital
Jan 2027Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases · Phase 3 · M.D. Anderson Cancer Center
Jan 2027The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies · Phase 3 · Stephen Lownie
Mar 2027Effect of Different Anesthetic Drugs on Electrocorticography (ECOG). · Phase 3 · Children's Cancer Hospital Egypt 57357
Mar 2027Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases · Phase 3 · NRG Oncology
Apr 2027Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM · Phase 3 · Northwell Health

Who these studies take

Of the 423 Brain Neoplasms studies recruiting now, 284 (67%) set no upper age limit and 82 (19%) stop at 75 or younger. 80 (19%) take children under 18. 8 (2%) are for women only and 1 (<1%) for men only; 36 (9%) take healthy volunteers.

Recruiting studies that take each age, of 423
Age	Women	Men
10	71 (17%)	71 (17%)
18	399 (94%)	393 (93%)
30	381 (90%)	374 (88%)
40	372 (88%)	365 (86%)
50	370 (87%)	363 (86%)
65	367 (87%)	360 (85%)
75	352 (83%)	346 (82%)
85	315 (74%)	310 (73%)

Across all 2,440 studies, recruiting or not: 22% stop at 75 or younger and 15% at 65; 21% take children; 2% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Brain Neoplasms studies take

Of 252 phase 2 interventional studies under Brain Neoplasms, half reached primary completion within 61 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Phase 1	54 mo36–84 · 205 studies	—	56 mo36–84 · 176 studies
Phase 1/2	82 mo48–105 · 71 studies	—	82 mo48–102 · 49 studies
Phase 2	61 mo38–98 · 252 studies	43 mo24–55 · 44 studies	67 mo43–100 · 208 studies
Phase 3	81 mo48–269 · 56 studies	—	—
Interventional, no phase	64 mo35–125 · 317 studies	—	65 mo36–125 · 306 studies
Observational	82 mo41–269 · 199 studies	—	82 mo42–269 · 181 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Show 6 more

Lemborexant on Perioperative Sleep Quality in Patients With Brain Tumor Undergoing SurgeryOct 29, 2026NCT07903051
Impact of a Radiologic and Immunologic Signature on Cerebral Efficacy of Treatments in Lung Cancers With Brain MetastasisOct 29, 2026NCT07904013
Adverse Events During Physical Therapy in Neurocritical ICU PatientsOct 28, 2026NCT07901140
Ceritinib Treatment for Recurrent MeningiomasOct 23, 2026NCT07893197
IDH1-vac in Patients With Newly Diagnosed IDH1R132H-positive High-grade AstrocytomasOct 22, 2026NCT07888647
EXercise-induced PhysioLogical Adaptations In Neurological DisordersOct 20, 2026NCT07883720

Studies

Recruiting first, then most recently updated. Showing 50 of 2,440. Browse all 2,440 → or search them.