Drug
Pioglitazone clinical trials
Also written Actos, AD4833 and BR3006B.
- studies test it
- 341
- open now
- 28
- in phase 3
- 57
- first study started
- 2000
Keep track of what changes. Save the Pioglitazone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- Pioglitazone
- 226
Combined with it in one product
- ACTOS®
- 16
Studies by the year they started
338 studies that test it; most in 2008 (36)
| Year | Studies |
|---|---|
| 2000 | 4 |
| 2001 | 3 |
| 2002 | 7 |
| 2003 | 16 |
| 2004 | 13 |
| 2005 | 21 |
| 2006 | 20 |
| 2007 | 27 |
| 2008 | 36 |
| 2009 | 29 |
| 2010 | 17 |
| 2011 | 16 |
| 2012 | 11 |
| 2013 | 11 |
| 2014 | 8 |
| 2015 | 8 |
| 2016 | 14 |
| 2017 | 6 |
| 2018 | 11 |
| 2019 | 7 |
| 2020 | 9 |
| 2021 | 7 |
| 2022 | 9 |
| 2023 | 7 |
| 2024 | 7 |
| 2025 | 9 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 11
- Phase 1
- 53
- Phase 2
- 95
- Phase 3
- 57
- Phase 4
- 103
- No phase
- 43
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 84 · Other 257
Takeda (38) · The University of Texas Health Science Center at San Antonio (13) · University of Texas Southwestern Medical Center (7) · Stanford University (6) · Boehringer Ingelheim (6) · The University of Texas Health Science Center, Houston (5) · AstraZeneca (5) · Tehran University of Medical Sciences (5)
Often tested with
Tested in the same studies.
Metformin (41) · Sitagliptin (11) · Empagliflozin (11) · Alogliptin (11) · Dapagliflozin (9) · Linagliptin (5) · Insulin (4) · Vildagliptin (4)
Studies
Open first, then newest update. How each study uses Pioglitazone is read from its arms, and is right about nine times in ten.
Testing it · 341
- Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)RecruitingPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT03109288Written as Pioglitazone
- Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 FibrosisRecruitingPhase 4Madrigal Pharmaceuticals, Inc.NCT07848191Written as ACTOS/pioglitazone
- Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus ParticipantsRecruitingPhase 4The University of Texas Health Science Center at San AntonioNCT05838287Written as Pioglitazone
- Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)RecruitingNot applicableThe University of Texas Health Science Center at San AntonioNCT02969798Written as Pioglitazone
- Quantifying Hepatic Mitochondrial Fluxes in HumansRecruitingPhase 4The University of Texas Health Science Center at San AntonioNCT05305287Written as Pioglitazone
- Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes MellitusRecruitingPhase 2Mayo ClinicNCT06729996Written as Pioglitazone (PIO)
- Bioenergetic Effect of Pioglitazone in CLD-PHRecruitingPhase 2Emory UniversityNCT06336798Written as Pioglitazone 30mg
- SGLT2i, Pioglitazone, and Ketone Production in T1DRecruitingPhase 3The University of Texas Health Science Center at San AntonioNCT07056699Written as Pioglitazone 15 MG and 30mg
- An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard TherapyRecruitingPhase 2Fudan UniversityNCT07117630Written as Pioglitazone (PIO)
- A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO TrialRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT05946564Written as Pioglitazone (ACTOS®)
- Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or TirzepatideRecruitingPhase 4Stanford UniversityNCT06657209Written as Pioglitazone
- Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesRecruitingPhase 3The University of Texas Health Science Center at San AntonioNCT06246799Written as Pioglitazone
- Effect Clomiphene vs Clomiphene Along With Pioglitazone on Ovarian Stimulation RateRecruitingPhase 4PAEC General Hospital, IslamabadNCT07462065Written as Pioglitazone (PIO) + Clomiphene citrate
- Insulin Regulation of Lipolysis and Lipolysis ProteinsRecruitingEarly Phase 1Mayo ClinicNCT03866408Written as Pioglitazone
- Prevention of Progression of Prediabetes, Obesity and CV RiskRecruitingPhase 1The University of Texas Health Science Center at San AntonioNCT06446531Written as Actos
- Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver DiseaseNot yet recruitingPhase 4Badr UniversityNCT07180745Written as Pioglitazone (PIO)
- Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify the Decrease in HbA1c and Prevent the Increase in Plasma Ketone Concentration?Not yet recruitingPhase 4Dasman Diabetes InstituteNCT06922656Written as Pioglitazone 45 mg
- A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed)RecruitingPhase 1Boryung Pharmaceutical Co., LtdNCT07083401Written as Pioglitazone 30 mg
- A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fasting)RecruitingPhase 1Boryung Pharmaceutical Co., LtdNCT07083388Written as Pioglitazone 30 mg
- Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 DiabetesRecruitingPhase 4Seoul National University Bundang HospitalNCT06989723Written as Pioglitazone 15 MG [Actos]
See all 341 studies that test Pioglitazone →
Given in every arm · 27 — Pioglitazone is usual care beside what is tested
- A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 DiabetesRecruitingPhase 4Boryung Pharmaceutical Co., LtdNCT06972732Written as Dapagliflozin/Pioglitazone
- A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate CancerActive, not recruitingPhase 1Aragon Pharmaceuticals, Inc.NCT02592317Written as Pioglitazone
- A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Pioglitazone in Type 2 Diabetic PatientsCompletedPhase 3Astellas Pharma IncNCT01225081Written as Pioglitazone
- Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic ControlCompletedPhase 3University of BasrahNCT06107153Written as Pioglitazone 30mg
- Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Patients With Type 2 DiabetesCompletedPhase 3Novartis PharmaceuticalsNCT00099853Written as pioglitazone
- A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)TerminatedPhase 4Eli Lilly and CompanyNCT02072096Written as Pioglitazone
- Effect of Inhaled Insulin (AERx® iDMS) on Blood Glucose Control in Type 2 DiabetesTerminatedPhase 3Novo Nordisk A/SNCT00411892Written as pioglitazone
- A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin AloneCompletedPhase 3AstraZenecaNCT01095666Written as Pioglitazone
- A Study to Investigate the Effect of GSK1605786 on Hepatic Cytochrome P450, and BCRP and OATP1B1 Transport in Healthy Adult SubjectsCompletedPhase 1GlaxoSmithKlineNCT01489943Written as Pioglitazone 15 mg
- Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes MellitusCompletedPhase 3Daiichi SankyoNCT00789750Written as Pioglitazone
- Drug-drug Interaction Study With MDV3100 and a Cocktail of SubstratesCompletedPhase 1Astellas Pharma Europe B.V.NCT01911728Written as Pioglitazone
- A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)CompletedPhase 3Merck Sharp & Dohme LLCNCT01076075Written as Comparator: pioglitazone
- Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128)CompletedPhase 3Merck Sharp & Dohme LLCNCT00885352Written as Pioglitazone
- MK0431 (Sitagliptin) Pioglitazone Add-on Study for Patients With Type 2 Diabetes Mellitus (0431-055)(COMPLETED)CompletedPhase 3Merck Sharp & Dohme LLCNCT00372060Written as Comparator: pioglitazone
- Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)CompletedPhase 3Merck Sharp & Dohme LLCNCT00086515Written as Pioglitazone
- GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of PioglitazoneCompletedPhase 3SanofiNCT00763815Written as Pioglitazone
- Effect Of Exenatide Treatment on Liver Fat Content in Patients With DiabetesCompletedPhase 4Baylor College of MedicineNCT01432405Written as Pioglitazone
- Pioglitazone Add-on Study in Patients With Type 2 Diabetes MellitusCompletedPhase 3Merck Sharp & Dohme LLCNCT00086502Written as Comparator: Pioglitazone
- A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTSCompletedPhase 1Daiichi SankyoNCT02473627Written as Pioglitazone hydrochloride
- Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin AloneCompletedPhase 3AstraZenecaNCT00121667Written as Pioglitazone
Showing 20 of 27.
As the comparator · 41 — what is tested is compared with Pioglitazone
- Enavogliflozin vs. Pioglitazone on Glucose and AtherosclerosisRecruitingPhase 4Seoul National University Bundang HospitalNCT06399835Written as Pioglitazone
- Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes MellitusRecruitingPhase 3EMSNCT05028140Written as PIOGLITAZONE
- Adipose Tissue Heterogeneity and Its Link to Type 2 DiabetesRecruitingNot applicableKarolinska InstitutetNCT05501483Written as Pioglitazone 45 mg
- Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on MetforminTerminatedPhase 2Gilead SciencesNCT00814372Written as Actos
- A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Type 2 Diabetes MellitusCompletedPhase 2AmgenNCT01028963Written as pioglitazone
- Efficacy and Safety of Dapagliflozin in Patients with Non-alcoholic SteatohepatitisCompletedPhase 2Cairo UniversityNCT05254626Written as Pioglitazone 30 mg
- Hydroxychloroquine Versus Pioglitazone in Combination Treatment for Type 2 Diabetes MellitusTerminatedPhase 2Charles Drew University of Medicine and ScienceNCT02303405Written as Pioglitazone
- Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian SyndromeCompletedPhase 2Khyber Medical University PeshawarNCT04867252Written as Metformin (500 mg Twice a day), Pioglitazone (15 mg Twice a day)
- Study of Rivoglitazone in Type 2 Diabetes MellitusCompletedPhase 3Daiichi SankyoNCT00484198Written as Pioglitazone
- Efficacy and Safety of Evoglitin in Patients With Type 2 Diabetes and Non-alcoholic Fatty Liver DiseasesCompletedPhase 4Dong-A ST Co., Ltd.NCT03910361Written as Pioglitazone
- Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian SyndromeCompletedEarly Phase 1Khyber Medical University PeshawarNCT03117517Written as Metformin, Pioglitazone
- Canagliflozin (Invokana™) vs. Standard Dual Therapy Regimen for T2DM During RamadanCompletedPhase 4University of LeicesterNCT02694263Written as Pioglitazone
- Safety and Efficacy Study to Compare Vildagliptin to Pioglitazone as Adding on Metformin in Type 2 DiabetesCompletedPhase 4Pusan National University HospitalNCT01882907Written as Pioglitazone
- Study of NGM313 in Obese ParticipantsCompletedPhase 1NGM Biopharmaceuticals, IncNCT03298464Written as Pioglitazone
- A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)CompletedPhase 2Merck Sharp & Dohme LLCNCT01217073Written as Pioglitazone
- Dose-Ranging Study in Treatment Naive Type 2 Diabetes Mellitus(T2DM)CompletedPhase 2GlaxoSmithKlineNCT00500331Written as pioglitazone
- Response To Oral Agents in Diabetes (ROAD)- Pilot StudyCompletedPhase 4University of DundeeNCT00780715Written as Pioglitazone
- Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and PioglitazoneCompletedPhase 4Yonsei UniversityNCT02875821Written as metformin with pioglitazone
- MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)CompletedPhase 3Merck Sharp & Dohme LLCNCT00532935Written as Comparator: pioglitazone
- A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)CompletedPhase 3Merck Sharp & Dohme LLCNCT01076075Written as Comparator: pioglitazone
Showing 20 of 41.
Codes
What other systems call Pioglitazone · ClinicalTrials.gg INT006661
- MeSH (NLM) D000077205PioglitazoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) X4OV71U42SPIOGLITAZONEConfirmed FDA, NLM, Wikidata
- RxNorm 33738Confirmed FDA, Wikidata
- Wikidata Q417765(RS)-pioglitazoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C71633PioglitazoneOne source FDA
- DrugBank DB01132One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077205 | Pioglitazone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | X4OV71U42S | PIOGLITAZONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 33738 | — | Confirmed FDA, Wikidata |
| Wikidata | Q417765 | (RS)-pioglitazone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C71633 | Pioglitazone | One source FDA |
| DrugBank | DB01132 | — | One source Wikidata |
Also registered as pioglitazone hydrochloride (UNII JQT35NPK6C · RxNorm 259319).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.