Drug
Dipyrone clinical trials
Also written Metamizole.
- studies test it
- 23
- open now
- 5
- in phase 3
- 4
- first study started
- 1998
Keep track of what changes. Save the Dipyrone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Studies by the year they started
23 studies that test it; most in 2016 (3)
| Year | Studies |
|---|---|
| 1998 | 2 |
| 2004 | 1 |
| 2006 | 1 |
| 2007 | 1 |
| 2009 | 1 |
| 2010 | 2 |
| 2014 | 1 |
| 2016 | 3 |
| 2017 | 1 |
| 2018 | 2 |
| 2019 | 2 |
| 2020 | 1 |
| 2021 | 1 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 3
- Phase 3
- 4
- Phase 4
- 6
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 19
University Hospital, Basel, Switzerland (5) · Medical University of Silesia (2) · Jessa Hospital (2) · Boehringer Ingelheim (2) · Wolfson Medical Center (2) · University Children's Hospital Basel (1) · Baskent University (1) · University Center of Araraquara (1)
Often tested with
Tested in the same studies.
Acetaminophen (6) · Ibuprofen (4) · Lidocaine (1) · Proxymetacaine (1) · Papaverine (1) · Diclofenac hydroxyethylpyrrolidine (1) · Orphenadrine (1) · Tramadol (1)
Studies
Open first, then newest update. How each study uses Dipyrone is read from its arms, and is right about nine times in ten.
Testing it · 23
- Efficacy of Non-opioid Drugs in Addition to Opioid Therapy for Cancer Pain ManagementNot yet recruitingPhase 3University Hospital, Basel, SwitzerlandNCT07682558Written as Metamizole
- Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in AdultsRecruitingPhase 3Brainfarma Industria Química e Farmacêutica S/ANCT07626437Written as dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg
- Study Protocol: Impact of Metamizole (Optalgin®) on Anti-Xa Concentrations in Oncology Patients Receiving DOACsRecruitingNot applicableRambam Health Care CampusNCT07384013Written as metamizole
- Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT)Not yet recruitingPhase 4Wolfson Medical CenterNCT06950840Written as dipyrone
- Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back PainRecruitingPhase 4Insel Gruppe AG, University Hospital BernNCT04111315Written as Metamizole Sodium
- Paracetamol and Metamizole With SPI-guided Anaesthesia for VRSCompletedNot applicableMedical University of SilesiaNCT03389243Written as Metamizol
- Evaluation of the Added Value of Metamizole to Standard Postoperative Treatment After Ambulant Shoulder SurgeryCompletedNot applicableJessa HospitalNCT04703257Written as Metamizole
- Evaluation of the Added Value of Metamizole to Standard Post-operative Treatment After Ambulant SurgeryCompletedNot applicableJessa HospitalNCT04082728Written as Metamizole
- Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar ExtractionCompletedPhase 4University Hospital, Basel, SwitzerlandNCT02686021Written as Metamizole and Ibuprofen
- Inhibition Metamizole 2020CompletedPhase 1University Hospital, Basel, SwitzerlandNCT04621253Written as Novalgin
- Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine PatientsWithdrawnNot applicableWestern Galilee Hospital-NahariyaNCT01263652Written as Dipyrone
- Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy SubjectsCompletedPhase 1University Hospital, Basel, SwitzerlandNCT03990129Written as Metamizole
- Comparing Protocols for Analgesia Following Elective Cesarean SectionStatus unknownPhase 4Wolfson Medical CenterNCT03622489Written as Dipyrone
- Pharmacokinetics of Intravenous Metamizole in Children Less Than 6 Years OldCompletedPhase 2University Children's Hospital BaselNCT02660177Written as Metamizole
- SPI-directed Analgesia for Vitreoretinal SurgeriesCompletedNot applicableMedical University of SilesiaNCT02973581Written as Metamizol
- Optimal Analgesia in Acute GastroenteritisTerminatedPhase 3Hadassah Medical OrganizationNCT02711241Written as Dipyrone
- Effect of Metamizole (Dipyrone) on Renal Function in Salt-depleted Healthy SubjectsCompletedPhase 1University Hospital, Basel, SwitzerlandNCT01995006Written as metamizole
- Efficacy and Safety of Metamizole Versus Placebo as Antithermic Therapy in the Acute Phase of Ischemic StrokeTerminatedPhase 4Boehringer IngelheimNCT02184260Written as Metamizole
- Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate HeadacheCompletedPhase 3Boehringer IngelheimNCT02183220Written as Metamizol
- Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal AnesthesiaCompletedPhase 2Baskent UniversityNCT01858402Written as Dipyrone
See all 23 studies that test Dipyrone →
Given in every arm · 15 — Dipyrone is usual care beside what is tested
- Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially RestoredRecruitingNot applicableUniversidade Estadual Paulista Júlio de Mesquita FilhoNCT05916716Written as Sodium dipyrone
- Biofunctionalization of a Volume-stable Collagen Matrix (VCMX) for the Treatment of Single Gingival RecessionRecruitingNot applicableUniversidade Estadual Paulista Júlio de Mesquita FilhoNCT05916742Written as Sodium dipyrone
- Comparison of Two Pain-treatment Techniques After Cesarean SectionCompletedPhase 4Michał BorysNCT02804126Written as Metamizol
- TAP vs QLB in Patients After Cesarean DeliveryCompletedPhase 4Medical University of LublinNCT03404908Written as metamizole
- Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular AnaesthesiaCompletedPhase 4Łukasz KrzychNCT04691726Written as Metamizole
- Evaluation of the Roll of IV Fluids in the Treatment of Renal ColicWithdrawnPhase 4Sheba Medical CenterNCT03529097Written as Optalgin, Voltaren, Morphine
- Comparison of Two Flaps for Root CoverageCompletedNot applicableUniversidade Estadual Paulista Júlio de Mesquita FilhoNCT02814279Written as Sodium dipyrone
- Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.Status unknownNot applicableUniversidade Estadual Paulista Júlio de Mesquita FilhoNCT03594513Written as Sodium dipyrone
- Regional Analgesia After Cesarean SectionCompletedPhase 4Medical University of LublinNCT03244540Written as Metamizol
- SPI-directed Analgesia for Lumbar DiscectomyCompletedNot applicableMedical University of SilesiaNCT02971540Written as Metamizol
- A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)CompletedNot applicableUniversidade Estadual Paulista Júlio de Mesquita FilhoNCT02817763Written as sodium dipyrone
- Laparoscopic-guided TAP Block in Patients Undergoing Gastric BypassStatus unknownPhase 3Hospital General Universitario ElcheNCT03203070Written as Metamizol iv
- Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder PainCompletedPhase 4University of DebrecenNCT02445599Written as Metamizole-sodium
- Analgesia iv vs Epidural Analgesia vs Port-sites Infiltration After Laparoscopic Sleeve GastrectomyCompletedPhase 3Hospital General Universitario ElcheNCT02662660Written as Metamizole and Acetaminophen iv
- Metamizol for the Treatment of Neoplastic Chronic PainTerminatedPhase 4Boehringer IngelheimNCT02181920Written as Metamizole
As the comparator · 7 — what is tested is compared with Dipyrone
- Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third MolarsNot yet recruitingPhase 3EMSNCT06237231Written as DIPYRONE
- Fixed Combination of Dipyrone and Codeine for Controlling Pain After Pelvic-abdominal SurgeryCompletedPhase 3Brazilian Clinical Research InstituteNCT04641338Written as Dipyrone
- Efficacy and Safety of Tiradentes Association in the Treatment of Acute PainWithdrawnPhase 2EMSNCT04593329Written as DIPYRONE
- Efficacy and Safety of Canadá Association in the Treatment of Chronic PainWithdrawnPhase 2EMSNCT05125978Written as Dipyrone
- Delirium in Elderly Patients With Trauma of the HipTerminatedPhase 4Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT02689024Written as Dipyrone
- The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord TraumaWithdrawnPhase 3Masaryk UniversityNCT03255330Written as Metamizol
- Paracetamol Toxicity in Septic PatientsSuspendedPhase 3Barzilai Medical CenterNCT01182974Written as dypirone
Codes
What other systems call Dipyrone · ClinicalTrials.gg INT007382
- MeSH (NLM) D004177DipyroneConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 6429L0L52YDIPYRONEConfirmed FDA, NLM
- RxNorm 3523One source FDA
- NCI Thesaurus C65435DipyroneOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004177 | Dipyrone | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 6429L0L52Y | DIPYRONE | Confirmed FDA, NLM |
| RxNorm | 3523 | — | One source FDA |
| NCI Thesaurus | C65435 | Dipyrone | One source FDA |
Also registered as metamizole (UNII 934T64RMNJ · RxNorm 3523) and metamizole sodium (UNII VSU62Z74ON · RxNorm 1537943).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.