Drug
Proxymetacaine clinical trials
Also written Alcaine and Proparacaine.
- studies test it
- 11
- open now
- 0
- in phase 3
- 1
- first study started
- 2005
How studies write it
Studies that test it under each name
Studies by the year they started
11 studies that test it; most in 2016 (3)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2012 | 1 |
| 2016 | 3 |
| 2020 | 3 |
| 2022 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 3
- 1
- Phase 4
- 4
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 11
London Vision Clinic (1) · Mayo Clinic (1) · Prisma Health-Upstate (1) · Medical University of Silesia (1) · Retina Vitreous Associates of Florida (1) · Illinois Retina Associates (1) · London Health Sciences Centre (1) · William Beaumont Hospitals (1)
Often tested with
Tested in the same studies.
Sodium Chloride (2) · Potassium Chloride (2) · Calcium Chloride (2) · Magnesium Chloride (2) · Sodium Acetate (2) · Sodium Citrate (2) · Tobramycin (1) · Dexamethasone (1)
Studies
Open first, then newest update. How each study uses proxymetacaine is read from its arms, and is right about nine times in ten.
Testing it · 11
- VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High MyopiaCompletedNot applicableLondon Vision ClinicNCT02528123Written as Proxymetacaine 0.5%
- Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal InjectionsCompletedNot applicableMayo ClinicNCT02951351Written as Proparacaine
- Wearing-Off Period of Pharmacological Dilation and AnisocoriaCompletedPhase 4Prisma Health-UpstateNCT05238233Written as Proparacaine Hydrochloride
- Does Topical Ophthalmic Anesthetic Prior to Probing and Irrigation Decrease Pain?TerminatedPhase 4William Beaumont HospitalsNCT04229771Written as Proparacaine Hydrochloride ophthalmic solution, USP 0.5%
- Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?Status unknownPhase 4Louisiana State University Health Sciences Center in New OrleansNCT05663684Written as Proparacaine Hydrochloride ophthalmic solution, USP 0.5%
- Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)Status unknownPhase 4Beeran Meghpara, MDNCT04283331Written as Proparacaine Ophthalmic
- SPI-directed Analgesia for Vitreoretinal SurgeriesCompletedNot applicableMedical University of SilesiaNCT02973581Written as Proxymetacaine
- Anesthesia Preference for Intravitreal Injection: Topical or SubconjunctivalCompletedNot applicableRetina Vitreous Associates of FloridaNCT01640171Written as Proparacaine Hydrochloride 0.5% Drop
- Proparacaine and Mydriatic Eye DropsTerminatedNot applicableChildren's Hospital of PhiladelphiaNCT01266824Written as Proparacaine Hydrochloride Ophthalmic Solution
- Patient Assessment of Topical Anesthetic Effectiveness for Intravitreal InjectionsCompletedPhase 3Illinois Retina AssociatesNCT01027611Written as proparacaine HCL 0.5%
- Proparacaine vs Placebo for Corneal InjuriesCompletedPhase 1London Health Sciences CentreNCT00620997Written as Proparacaine drops 0.05%
Given in every arm · 4 — proxymetacaine is usual care beside what is tested
- Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle ClosureStatus unknownNot applicableSun Yat-sen UniversityNCT02613013Written as Proparacaine
- Comparing Ropivacaine and Bupivacaine in DTFNB Anesthesia in Patients Undergoing PhacoemulsificationCompletedNot applicableGovernment Medical College, HaldwaniNCT02925832Written as Proparacaine
- Subfoveal Choroidal Thickness After Surgery for Age-related CataractsCompletedNot applicableSun Yat-sen UniversityNCT02895074Written as Proparacaine hydrochloride
- Comparison of In-the-bag Stability Between Single-piece and Three-piece Intraocular LensCompletedNot applicableSun Yat-sen UniversityNCT02609997Written as proparacaine
As the comparator · 2 — what is tested is compared with proxymetacaine
- Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal InjectionsEnrolling by invitationPhase 4Harrow IncNCT07456826Written as Proparacaine Hydrochloride Ophthalmic Solution 0.5%
- A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric PopulationCompletedPhase 3American Genomics, LLCNCT05325853Written as Proparacaine Ophthalmic
Codes
What other systems call proxymetacaine · ClinicalTrials.gg INT002347
- MeSH (NLM) C005717proxymetacaineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) B4OB0JHI1XPROPARACAINEConfirmed FDA, NLM
- RxNorm 34905One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C005717 | proxymetacaine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | B4OB0JHI1X | PROPARACAINE | Confirmed FDA, NLM |
| RxNorm | 34905 | — | One source FDA |
Also registered as proparacaine hydrochloride (UNII U96OL57GOY · RxNorm 227778).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.