Inflammation clinical trials
The registry lists 3,536 studies for Inflammation across more than 10 countries. 642 are recruiting or about to start. 622 of them are mainly about Inflammation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
Get an email when these change. Save the Inflammation studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
Emory University (28) · Radboud University Medical Center (25) · University of Florida (24) · University of California, Los Angeles (23) · Massachusetts General Hospital (22) · University of Aarhus (22) · Novo Nordisk A/S (21) · Universidade Federal Fluminense (20)
What is being tested here
Drugs under test in Inflammation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Colchicine | 14 | 12 | 34 |
| Omega-3 fatty acid | 5 | 4 | 30 |
| Semaglutide | 5 | 0 | 6 |
| Atorvastatin | 4 | 3 | 21 |
| Royal Jelly | 4 | 0 | 4 |
| Interleukin 1 Receptor Antagonist Protein | 3 | 2 | 19 |
| Tocilizumab | 3 | 1 | 11 |
| Quercetin | 3 | 0 | 5 |
| Baricitinib | 3 | 1 | 4 |
| 11C-PS13 | 3 | 0 | 3 |
Drug classes tested here GLP-1 receptor agonists 5 open · Tyrosine kinase inhibitors (TKIs) 5 open · JAK inhibitors 5 open · NSAIDs 4 open · Corticosteroids 4 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Colchicine and Inflammation in Aortic Stenosis · Phase 3 · Radboud University Medical Center
- Dec 2026Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis · Phase 3 · Ain Shams University
- Dec 2026Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women · Phase 3 · Cedars-Sinai Medical Center
- Dec 2026Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia · Phase 3 · Ottawa Heart Institute Research Corporation
- Dec 2026Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare · Phase 3 · Olatec Therapeutics, Inc.
- Jun 2027Design and Rationale of the COLT Study · Phase 3 · Azienda Sanitaria Locale ASL 6, Livorno
- Jul 2027The Effect of Nicorandil on Rheumatoid Arthritis Patients · Phase 3 · Ain Shams University
- Jul 2027Colchicine for Autoimmune and Subacute Thyroiditis · Phase 3 · Mansoura University
- Sep 2027The Danish Out-of-Hospital Cardiac Arrest Study · Phase 3 · Christian Hassager
- Sep 2027PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation · Phase 3 · Major Extremity Trauma Research Consortium
Who these studies take
Of the 462 Inflammation studies recruiting now, 174 (38%) set no upper age limit and 207 (45%) stop at 75 or younger. 56 (12%) take children under 18. 40 (9%) are for women only and 7 (2%) for men only; 165 (36%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 37 (8%) | 37 (8%) |
| 18 | 333 (72%) | 306 (66%) |
| 30 | 359 (78%) | 331 (72%) |
| 40 | 373 (81%) | 345 (75%) |
| 50 | 383 (83%) | 364 (79%) |
| 65 | 351 (76%) | 334 (72%) |
| 75 | 284 (61%) | 273 (59%) |
| 85 | 222 (48%) | 213 (46%) |
Across all 3,536 studies, recruiting or not: 50% stop at 75 or younger and 36% at 65; 11% take children; 8% are for women only and 6% for men only; 41% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Inflammation studies take
Of 149 phase 2 interventional studies under Inflammation, half reached primary completion within 29 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 21 mo10–51 · 82 studies | — | 28 mo17–56 · 63 studies |
| Phase 1/2 | 29 mo13–60 · 46 studies | — | 35 mo14–62 · 40 studies |
| Phase 2 | 29 mo16–56 · 149 studies | 17 mo10–26 · 36 studies | 45 mo23–64 · 113 studies |
| Phase 2/3 | 24 mo11–54 · 30 studies | — | — |
| Phase 3 | 27 mo17–50 · 68 studies | 22 mo11–28 · 21 studies | 44 mo21–63 · 47 studies |
| Phase 4 | 24 mo13–52 · 86 studies | — | 25 mo12–52 · 79 studies |
| Interventional, no phase | 18 mo8–36 · 924 studies | 12 mo6–24 · 47 studies | 18 mo8–36 · 877 studies |
| Observational | 40 mo18–85 · 370 studies | — | 41 mo18–85 · 354 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting9
- Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection FractionNov 10, 2026NCT06217120
- Ticagrelor for Inflammation and Cardiovascular Risk in Patients With Chronic Kidney DiseaseNov 10, 2026NCT07911124
- Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in HumansNov 4, 2026NCT07602166
- Predictive Value of Inflammatory Biomarkers for Mirabegron Response in Women With Overactive BladderNov 3, 2026NCT07773532
- Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in KidsOct 30, 2026NCT06882772
Show 4 moreShow fewer
- CRP Apheresis in Infarct-Related Cardiogenic ShockOct 27, 2026NCT07687017
- Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle SurgeryOct 22, 2026NCT07802106
- Stem Cell Therapy for Intracerebral HemorrhageOct 20, 2026NCT06862388
- Suppressive Functions of Regulatory T Cells in MigraineOct 14, 2026NCT07067112
Results posted1
Stopped3
- Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin TreatmentWithdrawnNov 3, 2026NCT04177303
- The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs StudiesSuspendedOct 29, 2026NCT06454344
- The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )TerminatedOct 21, 2026NCT03999580
Newly registered24
- Mechanisms Within the Autonomic Nervous SysTEm undeRlying MusIc Therapy's aNalgesic Effects in Sickle Cell Disease (MASTERMIND)Nov 10, 2026NCT07928089
- Mesenchymal Stem Cell Exosomes Alone or Combined With HUVEC Exosomes in Non-Dialysis Chronic Kidney DiseaseNov 6, 2026NCT07922889
- Fecal Microbiota Transplantation (FMT) to Slow Biological AgingNov 3, 2026NCT07912164
- Dupilumab in Major Depressive DisorderNov 2, 2026NCT07908563
- The Immunobiological Mechanisms of Depression in PerimenopauseNov 2, 2026NCT07910552
Show 19 moreShow fewer
- Effects of Taurine Supplementation and Morning or Evening High-intensity Exercise on Circadian Clock Genes and Inflammatory Parameters in Adult Women With ObesityNov 2, 2026NCT07910747
- Ticagrelor for Inflammation and Cardiovascular Risk in Patients With Chronic Kidney DiseaseNov 2, 2026NCT07911124
- Effects Of Periodontal Therapy In Patients With Inflammatory Bowel DiseaseOct 30, 2026NCT07905859
- Effect of Bee Venom on T Regulatory Cells and Inflammation in Hemodialysis Patients: a Prospective Study ThesisOct 30, 2026NCT07907588
- Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study)Oct 27, 2026NCT07897097
- Efficacy of MAGNESIO TOTAL on Sleep Quality and Quality of Life in AdultsOct 26, 2026NCT07894562
- Inflammatory Pathways Modulated by Prenatal Mindfulness: A Route to Improve Maternal Child Emotional Well Being and Whole Person HealthOct 23, 2026NCT07892326
- Exercise, Mediterranean Diet and Inflammation in Heart FailureOct 21, 2026NCT07885514
- Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's DiseaseOct 20, 2026NCT07882108
- Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess AdiposityOct 20, 2026NCT07883031
- IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With ObesityOct 20, 2026NCT07884058
- Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune ThyroiditisOct 19, 2026NCT07879690
- Vascular Inflammation in Atherosclerosis - Whole Body Molecular PET/CT Imaging Using Folate Receptor βOct 16, 2026NCT07877324
- Egg Albumin and Agave Fructans With Exercise in HemodialysisOct 16, 2026NCT07877545
- Effect of Curcumin Topical Spray on Wound Healing After Tooth ExtractionOct 15, 2026NCT07874789
- Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic SurgeryOct 14, 2026NCT07872683
- Functional Foods for HealthOct 13, 2026NCT07871682
- Investigation of the Effectiveness of Spinal Stabilization Exercises Added to Aerobic Exercise in Women With Polycystic Ovary SyndromeOct 13, 2026NCT07871851
- Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue ExerciseOct 13, 2026NCT07871942
Studies
Recruiting first, then most recently updated. Showing 50 of 3,536. Browse all 3,536 → or search them.
- Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection FractionRecruitingNCT06217120Phase 21 country
- Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruitingNCT076195471 country
- Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous SystemRecruitingNCT007943521 country
- Investigation of the Effectiveness of Spinal Stabilization Exercises Added to Aerobic Exercise in Women With Polycystic Ovary SyndromeEnrolling by invitationNCT07871851Not applicable1 country
- Ticagrelor for Inflammation and Cardiovascular Risk in Patients With Chronic Kidney DiseaseRecruitingNCT07911124Phase 21 country
- Mechanisms Within the Autonomic Nervous SysTEm undeRlying MusIc Therapy's aNalgesic Effects in Sickle Cell Disease (MASTERMIND)Not yet recruitingNCT07928089Not applicable1 country
- The Prognosis of Patients After PCI:a Multi-center Study in ChinaRecruitingNCT056140501 country
- Secukinumab Open Label Roll-over Extension ProtocolRecruitingNCT04638647Phase 422 countries
- Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway InflammationRecruitingNCT00595491Phase 11 country
- Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's DiseaseRecruitingNCT07651319Phase 1/21 country
- Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)RecruitingNCT05531786Phase 1/21 country
- Beta-Blocker Influences on Inflammatory and Neural Responses to StressRecruitingNCT06263452Phase 41 country
- Diagnosis and Management of Inflammatory and Infectious DiseasesRecruitingNCT005577261 country
- Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune ThyroiditisNot yet recruitingNCT07879690Not applicable1 country
- Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in HumansRecruitingNCT07602166Phase 21 country
- Our Voices Matter: Intervention for Depression in YouthRecruitingNCT07216326Not applicable1 country
- Oxidative Stress and Inflammatory Biomarkers in Gaucher DiseaseRecruitingNCT024373961 country
- A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's DiseaseRecruitingNCT07157735Phase 21 country
- Fecal Microbiota Transplantation (FMT) to Slow Biological AgingNot yet recruitingNCT07912164Not applicable
- Ex Vivo Study of Leukocyte Responses in the Blood of Patients With Leptospirosis and ex Vivo Testing of a New Host-targeted Therapeutic Strategy to Restore Phagocytosis of LeptospiraNot yet recruitingNCT07611591
- Predictive Value of Inflammatory Biomarkers for Mirabegron Response in Women With Overactive BladderRecruitingNCT077735321 country
- Dupilumab in Major Depressive DisorderRecruitingNCT07908563Phase 21 country
- Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingNCT07281456Phase 21 country
- The Immunobiological Mechanisms of Depression in PerimenopauseRecruitingNCT079105521 country
- PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseRecruitingNCT04396873Phase 11 country
- Effects of Taurine Supplementation and Morning or Evening High-intensity Exercise on Circadian Clock Genes and Inflammatory Parameters in Adult Women With ObesityNot yet recruitingNCT07910747Not applicable1 country
- Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in KidsRecruitingNCT06882772Phase 1/21 country
- Effects Of Periodontal Therapy In Patients With Inflammatory Bowel DiseaseRecruitingNCT079058591 country
- Evaluation and Long-Term Follow-up of Patients With Inflammatory DisordersEnrolling by invitationNCT000013511 country
- Natural History of the Human Biological Response to Environmental Exposure and InjuryRecruitingNCT048889231 country
- Role of Inflammation in Vascular Phenotype Associated With E-cigarette UseRecruitingNCT06489249Early Phase 11 country
- Investigating Novel Strategies in Pediatric Immune Responses and Microbiome Environment: Comprehensive Lung Disease Investigation in Children.Enrolling by invitationNCT067460771 country
- CRP Apheresis in Infarct-Related Cardiogenic ShockRecruitingNCT07687017Not applicable1 country
- Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study)Not yet recruitingNCT07897097Not applicable
- Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via InfliximabRecruitingNCT06136546Phase 21 country
- The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.RecruitingNCT07848594Not applicable1 country
- Effect of Curcumin Topical Spray on Wound Healing After Tooth ExtractionRecruitingNCT07874789Not applicable1 country
- Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)RecruitingNCT04339907Not applicable1 country
- Combination of NMDA-enhancing and Anti-inflammatory Treatments for SchizophreniaRecruitingNCT04917302Phase 21 country
- Inflammatory Pathways Modulated by Prenatal Mindfulness: A Route to Improve Maternal Child Emotional Well Being and Whole Person HealthNot yet recruitingNCT07892326Not applicable1 country
- Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile CorporaNot yet recruitingNCT03463239Phase 11 country
- A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)RecruitingNCT07646587Phase 22 countries
- Nutrition in Rheumatoid ArthritisEnrolling by invitationNCT06831331Not applicable1 country
- Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle SurgeryRecruitingNCT078021061 country
- Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related ConditionsRecruitingNCT035104421 country
- Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney InjuryRecruitingNCT05758077Not applicable1 country
- Ginger-PD: Ginger as a Modifier of Ghrelin Levels and Gut Function in Parkinson's DiseaseRecruitingNCT07882108Not applicable1 country
- Exercise, Mediterranean Diet and Inflammation in Heart FailureNot yet recruitingNCT07885514Not applicable
- Functional Foods for HealthNot yet recruitingNCT07871682Not applicable1 country
- IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With ObesityNot yet recruitingNCT07884058Phase 2