Drug
Codeine clinical trials
- studies test it
- 33
- open now
- 0
- in phase 3
- 5
- first study started
- 2005
How studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
33 studies that test it; most in 2012 (6)
| Year | Studies |
|---|---|
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 3 |
| 2011 | 1 |
| 2012 | 6 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 1 |
| 2017 | 3 |
| 2018 | 3 |
| 2021 | 1 |
| 2023 | 2 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 6
- Phase 2
- 2
- Phase 3
- 5
- Phase 4
- 15
- No phase
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 29
Universitaire Ziekenhuizen KU Leuven (3) · Montefiore Medical Center (2) · Pontificia Universidad Catolica de Chile (1) · ibrahim doğru (1) · Albert Einstein College of Medicine (1) · Cairo University (1) · Yuzuncu Yıl University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1)
Often tested with
Tested in the same studies.
Acetaminophen (13) · Ibuprofen (7) · Oxycodone (5) · Naproxen (3) · Hydrocodone (2) · Caffeine (2) · Metoclopramide (2) · Diclofenac (2)
Studies
Open first, then newest update. How each study uses Codeine is read from its arms, and is right about nine times in ten.
Testing it · 33
- CHAO Tos: Codeina, HederA Helix, LevOdropropizina Para la TOSCompletedPhase 4Pontificia Universidad Catolica de ChileNCT06907355Written as Codeine
- Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental PainCompletedPhase 4ibrahim doğruNCT06916234Written as Naproxen Sodium + Codeine Phosphate
- Colonic Motor Patterns in Healthy VolunteersCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT05770960Written as codeine phosphate
- An Randomized Control Trial Comparing Two Drug Combinations for Pain Management After Third Molars SurgerySuspendedNot applicableUniversity of ZimbabweNCT04874675Written as diclofenac / acetaminophen /codeine
- Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)CompletedPhase 2Albert Einstein College of MedicineNCT03173456Written as codeine/APAP
- Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute PulpitisCompletedNot applicableCairo UniversityNCT04202406Written as Acetaminophen and codeine and caffeine
- Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial PainCompletedPhase 4Yuzuncu Yıl UniversityNCT04066426Written as naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol
- Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the EDTerminatedNot applicableMount Sinai Hospital, CanadaNCT03478423Written as Codeine
- Codeine on Pharyngeal and Esophageal MotilityCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT03784105Written as Codeine Phosphate
- A Study of Oral Codeine Sulfate in Pediatric Patients With Post-procedural PainTerminatedPhase 3Roxane LaboratoriesNCT01676493Written as Codeine
- Codeine in Mechanically Ventilated NeonatesCompletedPhase 1Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT01322204Written as Codeine
- Clinical Evaluation of the VIPUN Balloon Catheter 0.1CompletedNot applicableUniversitaire Ziekenhuizen KU LeuvenNCT03239821Written as Codeine Phosphate
- Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge DischargeCompletedPhase 3Montefiore Medical CenterNCT01402375Written as Codeine (first trial)
- A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.CompletedNot applicableSt. Louis UniversityNCT02295280Written as Codeine
- Comparative Efficacy of 4 Oral AnalgesicsCompletedPhase 4Montefiore Medical CenterNCT02455518Written as Codeine/acetaminophen
- Treatment of Chronic Pain From OsteoarthritisWithdrawnPhase 4Fondazione IRCCS Policlinico San Matteo di PaviaNCT02032927Written as Codeine/paracetamol
- Codeine Phosphate/Guaifenesin ER Tablet 30 mg/600 mg Steady State Clinical StudyCompletedPhase 1Nexgen Pharma, IncNCT02572375Written as Codeine Phosphate/Guaifenesin ER Tablet
- Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their CombinationCompletedPhase 4Ullevaal University HospitalNCT00921700Written as Ibuprofen + Paracetamol + Codeine
- Codeine Plus Paracetamol Versus Placebo for PRK Post-operative PainCompletedPhase 3University of Sao Paulo General HospitalNCT02625753Written as Codeine
- Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.CompletedPhase 4University of Sao PauloNCT02547896Written as Codeine + Diclofenac
See all 33 studies that test Codeine →
Given in every arm · 1 — Codeine is usual care beside what is tested
As the comparator · 5 — what is tested is compared with Codeine
- Fixed Combination of Dipyrone and Codeine for Controlling Pain After Pelvic-abdominal SurgeryCompletedPhase 3Brazilian Clinical Research InstituteNCT04641338Written as Codeine
- Cannabinoid vs Opioid for Photorefractive Keratectomy Pain ControlCompletedPhase 2University of FloridaNCT05477875Written as oral codeine/acetaminophen
- COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICACompletedPhase 3Pakistan Institute of Medical SciencesNCT05626140Written as Codeine Phosphate
- A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)CompletedPhase 3Organon and CoNCT00694369Written as Comparator: acetaminophen + codeine
- A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to OsteoarthritisCompletedPhase 4Napp Pharmaceuticals LimitedNCT00784810Written as Codeine/Paracetamol
Codes
What other systems call Codeine · ClinicalTrials.gg INT007246
- MeSH (NLM) D003061CodeineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Q830PW7520CODEINEConfirmed FDA, Wikidata
- RxNorm 2670One source FDA
- Wikidata Q98915715codeine monohydrateConfirmed FDA, Wikidata
- NCI Thesaurus C383CodeineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003061 | Codeine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Q830PW7520 | CODEINE | Confirmed FDA, Wikidata |
| RxNorm | 2670 | — | One source FDA |
| Wikidata | Q98915715 | codeine monohydrate | Confirmed FDA, Wikidata |
| NCI Thesaurus | C383 | Codeine | One source FDA |
Also registered as codeine anhydrous (UNII UX6OWY2V7J · RxNorm 1545976) and codeine phosphate (UNII GSL05Y1MN6 · RxNorm 2672).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.