Drug
Naproxen clinical trials
Also written Naprosyn and Aleve.
- studies test it
- 150
- open now
- 11
- in phase 3
- 33
- first study started
- 2000
Keep track of what changes. Save the Naproxen studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
148 studies that test it; most in 2008 (19)
| Year | Studies |
|---|---|
| 2000 | 2 |
| 2003 | 3 |
| 2004 | 7 |
| 2005 | 2 |
| 2006 | 9 |
| 2007 | 5 |
| 2008 | 19 |
| 2009 | 6 |
| 2010 | 11 |
| 2011 | 7 |
| 2012 | 4 |
| 2013 | 2 |
| 2014 | 11 |
| 2015 | 9 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 9 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 5 |
| 2022 | 5 |
| 2023 | 5 |
| 2024 | 7 |
| 2025 | 3 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 39
- Phase 2
- 17
- Phase 3
- 33
- Phase 4
- 43
- No phase
- 16
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 79 · Other 71
Bayer (24) · Pfizer (8) · GlaxoSmithKline (6) · AstraZeneca (6) · POZEN (6) · Northwestern University (4) · Merck Sharp & Dohme LLC (4) · Dr. Reddy's Laboratories Limited (4)
Often tested with
Tested in the same studies.
Sumatriptan (12) · Acetaminophen (11) · Celecoxib (11) · Esomeprazole (10) · Lidocaine (4) · Tramadol (3) · Codeine (3) · Aspirin (3)
Studies
Open first, then newest update. How each study uses Naproxen is read from its arms, and is right about nine times in ten.
Testing it · 150
- Human Experimental Models of Pain (HEMP)Not yet recruitingNot applicableNational Center for Complementary and Integrative Health (NCCIH)NCT07549490Written as Naproxen
- Naproxen Versus Placebo as Adjunct Treatment of CellulitisNot yet recruitingPhase 3Ottawa Hospital Research InstituteNCT07665476Written as enteric-coated naproxen
- NSAIDS Following Elective Lumbar Spine FusionEnrolling by invitationPhase 3Rothman Institute OrthopaedicsNCT07743606Written as Naproxen
- A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch SyndromeRecruitingPhase 2M.D. Anderson Cancer CenterNCT05411718Written as Naproxen
- Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer PatientsEnrolling by invitationNot applicableMayo Hospital LahoreNCT07606638Written as Pregabalin + Naproxen Sodium
- A Study to Evaluate the Pharmacokinetics and Food-effect of IN-M00002 Tablet in Healthy Adult VolunteersNot yet recruitingPhase 1HK inno.N CorporationNCT07277712Written as Naproxen
- Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in GoutRecruitingPhase 4Massachusetts General HospitalNCT04875702Written as Naproxen 250 MG
- NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL)RecruitingPhase 4Endeavor HealthNCT06861920Written as Naproxen Sodium 550mg
- Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative RadiotherapyNot yet recruitingPhase 2American University of Beirut Medical CenterNCT06903585Written as Naproxen (Proxen S)
- Pain Control After Lumbar Spine FusionEnrolling by invitationPhase 4Rothman Institute OrthopaedicsNCT06484192Written as Naproxen 500 Mg
- Optimal Treatment of Acute Skeletal Muscle InjuryNot yet recruitingNot applicableBispebjerg HospitalNCT06274151Written as Naproxen 500 Mg
- Mechanistic Characterization of Uterine PainCompletedPhase 4Endeavor HealthNCT04145518Written as Naproxen Sodium
- Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative PainCompletedPhase 2/3Dow University of Health SciencesNCT05982392Written as Naproxen Sodium
- Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDASTerminatedPhase 4Massachusetts General HospitalNCT04015596Written as Naproxen Sodium
- NSAIDs vs. Coxibs in the Presence of AspirinTerminatedPhase 4Platelet and Thrombosis Research, LLCNCT03699293Written as naproxen sodium 550mg tablet
- PK,PD and DDI of Epaminurad and Naproxen in Healthy VolunteersCompletedPhase 1JW PharmaceuticalNCT06435442Written as Epaminurad, Naproxen
- Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee OsteoarthritisActive, not recruitingPhase 4Northwestern UniversityNCT05430230Written as Naproxen 500 Mg
- Symptomatic Management of Lyme ArthritisTerminatedPhase 3Desiree Neville, MDNCT04038346Written as Naproxen
- Effect of Oral Analgesics on Post-op PainCompletedEarly Phase 1Armed Forces Institute of Dentistry, PakistanNCT07204379Written as Naproxen
- Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 TrialsTerminatedPhase 2The University of Texas Health Science Center, HoustonNCT04115098Written as Naproxen
See all 150 studies that test Naproxen →
Given in every arm · 22 — Naproxen is usual care beside what is tested
- Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill QuantityEnrolling by invitationPhase 4AdventHealthNCT07750639Written as Naproxen
- Duloxetine for LBPRecruitingPhase 4Montefiore Medical CenterNCT05851976Written as Naproxen
- Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)CompletedPhase 1/2National Cancer Institute (NCI)NCT03493945Written as Naproxen
- A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)CompletedPhase 2Merck Sharp & Dohme LLCNCT03654326Written as Naproxen
- Novel Non-opioid Post-surgical Pain Treatment in FemalesWithdrawnPhase 2Northwestern UniversityNCT05087914Written as Naproxen
- Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and HipTerminatedPhase 2Regeneron PharmaceuticalsNCT03949673Written as Naproxen
- Treatment Study of Steroid Injection and Physical Therapy for Acute Lateral EpicondylitisCompletedPhase 4University of OsloNCT00826462Written as Naproxen
- Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL ReconstructionStatus unknownPhase 3Rothman Institute OrthopaedicsNCT05161221Written as Naproxen 500 Mg
- Efficacy of Multimodal Analgesia Following Hip ArthroscopyCompletedNot applicableWestern University, CanadaNCT03351439Written as Naprosyn
- MAST Trial: Multi-modal Analgesic Strategies in TraumaCompletedPhase 4The University of Texas Health Science Center, HoustonNCT03472469Written as Naproxen
- Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDsStatus unknownPhase 1Daewoong Pharmaceutical Co. LTD.NCT04490434Written as Naproxen
- The Effect of Turmeric on New Onset Primary DysmenorrheaCompletedNot applicableBatman Training and Research HospitalNCT04183556Written as Naproxen
- Is Kinesio Taping Effective to the Radial Nerve in Patients With Lateral Epicondylitis?CompletedNot applicableAnkara Education and Research HospitalNCT03794219Written as oral naproxen
- Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With GoutCompletedPhase 4Menarini International Operations Luxembourg SANCT02500641Written as Naproxen
- Diazepam Use With Standard Management for Acute Low Back PainCompletedPhase 2/3Montefiore Medical CenterNCT02646124Written as Naproxen
- A Randomized Study of Three Medication Regimens for Acute Low Back PainCompletedPhase 4Montefiore Medical CenterNCT01587274Written as Naproxen
- Orphenadrine and Methocarbamol for LBPCompletedPhase 4Montefiore Medical CenterNCT02665286Written as Naproxen
- Gastrointestinal Integrity After Naproxen + Rebamipide Versus Naproxen + PlaceboCompletedPhase 1Biolab Sanus FarmaceuticaNCT02632812Written as Naproxen tablet
- Characterize Flu-like Symptoms in Relapsing Multiple Sclerosis Patients Transitioning From Non-Pegylated Interferon Beta (IFN-β) Therapies to Peginterferon Beta-1a (BIIB017)CompletedPhase 3BiogenNCT01939002Written as naproxen
- Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With GoutCompletedPhase 3TakedaNCT02139046Written as Naproxen
Showing 20 of 22.
As the comparator · 65 — what is tested is compared with Naproxen
- Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment PainRecruitingPhase 4Dow University of Health SciencesNCT06562816Written as Naproxen Sodium 550mg
- Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber OpeningRecruitingPhase 4Dow University of Health SciencesNCT06344195Written as Naproxen Sodium 550mg
- A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental PainCompletedPhase 3Johnson & Johnson Consumer Inc. (J&JCI)NCT05761574Written as Naproxen Sodium
- A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the KneeCompletedPhase 2Astellas Pharma Europe B.V.NCT02611466Written as Naproxen
- Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative PainCompletedPhase 2Laboratorios LiomontNCT05995912Written as Naproxen
- An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064)CompletedPhase 3Organon and CoNCT00092729Written as Comparator: naproxen sodium
- Delirium in Elderly Patients With Trauma of the HipTerminatedPhase 4Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT02689024Written as Naproxen
- Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the KneeCompletedNot applicablePrimus PharmaceuticalsNCT00790985Written as Naproxen
- Study to Evaluate Efficacy and Safety of IW-6118 in Patients Undergoing Third Molar ExtractionCompletedPhase 2Ironwood Pharmaceuticals, Inc.NCT01107236Written as Naproxen Sodium
- RN624 In Adult Patients With Chronic Low Back PainCompletedPhase 2PfizerNCT00584870Written as Naproxen
- A Study of Tanezumab in Adults With Chronic Low Back PainCompletedPhase 2PfizerNCT00876187Written as Naproxen
- Tanezumab in Osteoarthritis of the Hip or Knee (2)CompletedPhase 3PfizerNCT00863304Written as naproxen
- Tanezumab In Osteoarthritis Of The Knee (2)CompletedPhase 3PfizerNCT00830063Written as naproxen
- Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or NaproxenCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00346216Written as Naproxen
- Comparison Of Ketorolac Tromethamine Versus Naproxen For Moderate to Severe Back Pain TreatmentCompletedPhase 3EMSNCT01471886Written as Naproxen
- Comparison Of Ketorolac Tromethamine Oral Drops Versus Naproxen For Moderate to Severe Back Pain TreatmentCompletedPhase 3EMSNCT01471899Written as Naproxen
- Safety and Efficacy of Celecoxib Versus Naproxen in the 6-month Treatment of Knee OsteoarthritisCompletedPhase 4Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00643799Written as Naproxen
- Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic PatientsCompletedPhase 3EMSNCT01670552Written as Naproxen + Esomeprazole
- A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the KneeCompletedPhase 2Purdue Pharma LPNCT03028870Written as Naproxen
- A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) PainTerminatedPhase 2PfizerNCT00418782Written as naproxen
Showing 20 of 65.
Codes
What other systems call Naproxen · ClinicalTrials.gg INT007870
- MeSH (NLM) D009288NaproxenConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 57Y76R9ATQNAPROXENConfirmed FDA, NLM, Wikidata
- RxNorm 7258Confirmed FDA, Wikidata
- Wikidata Q1215575naproxenConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C680NaproxenOne source FDA
- DrugBank DB00788One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009288 | Naproxen | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 57Y76R9ATQ | NAPROXEN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7258 | — | Confirmed FDA, Wikidata |
| Wikidata | Q1215575 | naproxen | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C680 | Naproxen | One source FDA |
| DrugBank | DB00788 | — | One source Wikidata |
Also registered as naproxen sodium (UNII 9TN87S3A3C · RxNorm 142442).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.