Breast Diseases clinical trials
The registry lists 148 studies for Breast Diseases across more than 10 countries. 26 are recruiting or about to start. 47 of them are mainly about Breast Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 14 narrower conditions too, such as Breast Neoplasms: 15,928 studies, 3,688 open.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
AstraZeneca (4) · Sysmex America, Inc. (4) · Syndax Pharmaceuticals (4) · Novartis Pharmaceuticals (3) · Medipol University (3) · Ma Zhe (3) · Zhejiang Cancer Hospital (2) · Huazhong University of Science and Technology (2)
What is being tested here
Drugs under test in Breast Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| AZD9833 | 1 | 3 | 3 |
| Letrozole | 1 | 1 | 3 |
| Tamoxifen | 1 | 1 | 2 |
| Suzetrigine | 1 | 0 | 1 |
| Elacestrant | 1 | 0 | 1 |
| STX-478 | 1 | 0 | 1 |
| Dalpiciclib | 1 | 0 | 1 |
| Sacubitril valsartan | 1 | 0 | 1 |
| Entinostat | 0 | 0 | 4 |
| Pyrotinib | 0 | 0 | 4 |
Drug classes tested here SERDs (estrogen receptor degraders) 2 open · Aromatase inhibitors 1 open · Tyrosine kinase inhibitors (TKIs) 5 · Opioids 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09) · Phase 3 · AstraZeneca
- Jul 2027Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation · Phase 3 · Alliance for Clinical Trials in Oncology
- Dec 2026Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer · Stemline Therapeutics, Inc.
- Dec 2026Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI Models · Peking Union Medical College Hospital
- Dec 2026Contrast-Free Magnetic Resonance Imaging for Breast Disease · Perspectum
- Dec 2026Lymphaticovenous Anastomosis as Treatment for Lymphedema · Odense University Hospital
- Mar 202718F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer. · Maastricht University Medical Center
- Jun 2027Suzetrigine for Non-Mastectomy Breast Surgery · University of California, San Diego
- Jun 2027Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors · Ensem Therapeutics
- Jul 2027Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast · Icahn School of Medicine at Mount Sinai
Who these studies take
Of the 20 Breast Diseases studies recruiting now, 14 (70%) set no upper age limit and 2 (10%) stop at 75 or younger. 2 (10%) take children under 18. 11 (55%) are for women only and 0 (0%) for men only; 4 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (10%) | 1 (5%) |
| 18 | 18 (90%) | 8 (40%) |
| 30 | 18 (90%) | 8 (40%) |
| 40 | 18 (90%) | 8 (40%) |
| 50 | 19 (95%) | 8 (40%) |
| 65 | 19 (95%) | 8 (40%) |
| 75 | 19 (95%) | 8 (40%) |
| 85 | 17 (85%) | 8 (40%) |
Across all 148 studies, recruiting or not: 26% stop at 75 or younger and 12% at 65; 9% take children; 70% are for women only and 1% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Breast Diseases studies take
Of 26 interventional studies with no phase under Breast Diseases, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 31 mo14–63 · 26 studies | — | — |
| Observational | 35 mo19–147 · 19 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 148. Browse all 148 → or search them.
- Evaluation of Scanning and Diagnostic Performance of an Autonomous Dual-Arm Breast Ultrasound RobotRecruitingNCT079150501 country
- A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast CancerRecruitingNCT07647328Phase 39 countries
- Phase 1/2 Study of ETX-636 in Participants With Advanced Solid TumorsRecruitingNCT06993844Phase 1/22 countries
- Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast CancerRecruitingNCT05386108Phase 1/210 countries
- ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono HealthRecruitingNCT075057971 country
- Suzetrigine for Non-Mastectomy Breast SurgeryEnrolling by invitationNCT07463430Phase 41 country
- A Study of Breast Cancer Risk Factors and Outcomes of People in FloridaRecruitingNCT067801761 country
- First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid TumorsRecruitingNCT05768139Phase 1/29 countries
- Efficacy and Safety of Dalpiciclib Combined With Endocrine Adjuvant Therapy for Early HR +/HER2- Breast Cancer: a Multicenter, Prospective Clinical StudyRecruitingNCT07581834Phase 21 country
- Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI ModelsRecruitingNCT075004281 country
- The Value of the O-RADS Radiological Classification in Predicting the Malignancy of Ovarian Masses in ChildrenRecruitingNCT073135141 country
- 18F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer.RecruitingNCT06335069Phase 21 country
- A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer PatientsRecruitingNCT070109391 country
- Breast 3DUS ABUS System ComparisonRecruitingNCT06118996Not applicable1 country
- Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)RecruitingNCT05465031Phase 41 country
- Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 StudyRecruitingNCT068058121 country
- Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast SurgeryRecruitingNCT06507345Not applicable1 country
- Endoscopic Anatomy of the Breast Fascia SystemRecruitingNCT066787761 country
- A Retrospective Real-world Study of Abemaciclib in HR+ Breast CancerNot yet recruitingNCT063412831 country
- Real World Evaluation of Lunit INSIGHT MMG TechnologyNot yet recruitingNCT062320701 country
- A Simplified Approach to Predicting the Malignancy of Breast Lesions: Nomogram in UltrasonographyNot yet recruitingNCT06185855
- PET-MRI for Axillary Staging in Node Negative Breast Cancer PatientsRecruitingNCT03374826Not applicable1 country
- Smart Optical and Ultrasound Diagnostic of Breast CancerRecruitingNCT05916703Not applicable1 country
- Effectiveness Validation of CELBREA® in Symptomatic Women or With Diagnostic Doubt of Breast Pathology (DETECT-BH)Enrolling by invitationNCT058571111 country
- A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric DisordersEnrolling by invitationNCT05395949Not applicable1 country
- A Registry Study of Breast Microseed TreatmentRecruitingNCT027012441 country
- Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)Active, not recruitingNCT04784715Phase 327 countries
- Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline MutationActive, not recruitingNCT04711109Phase 31 country
- A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced DiseaseActive, not recruitingNCT04711252Phase 327 countries
- Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)Active, not recruitingNCT04964934Phase 323 countries
- A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K MutationsActive, not recruitingNCT07038369Phase 14 countries
- Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic BreastActive, not recruitingNCT03304080Phase 1/21 country
- REGENERA Implant in Localized Non-malignant Breast Lesions Treated by Excision or Lumpectomy - Long-term Follow-upCompletedNCT055330991 country
- Contrast-Free Magnetic Resonance Imaging for Breast DiseaseActive, not recruitingNCT050061961 country
- Leflunomide in Previously Treated Metastatic Triple Negative CancersCompletedNCT03709446Phase 1/21 country
- Dotarem vs Gadobutrol Contrast for Breast MRICompletedNCT03730051Phase 41 country
- Robotic vs. Open NSM for Early Stage Breast CancerActive, not recruitingNCT05720039Not applicable1 country
- Evaluating the Value of Audio-guided Meditation During Breast Biopsy ProceduresCompletedNCT053439751 country
- Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense BreastsActive, not recruitingNCT048543041 country
- A Study to Compare PK, Immunogenicity and Safety of Trastuzumab of Incepta Pharmaceuticals Ltd With Trastuzumab (Roche)CompletedNCT06886659Phase 11 country
- The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar FormationCompletedNCT03887377Phase 2/31 country
- The Use of AI to Safely Reduce the Workload in Breast Cancer Screening With Mammography in Region ÖstergötlandCompletedNCT061873501 country
- Advanced Diffusion Tensor MRI for Breast CancerCompletedNCT047744711 country
- Prospective Phase II Study of Intraoperative Radiotherapy (IORT) in Elderly Patients with Small Breast CancerCompletedNCT01299987Not applicable1 country
- Surgical and Patient Reported Outcomes of Robotic Nipple-Sparing MastectomySuspendedNCT04151368Not applicable1 country
- Explore Association Models Between Environmental Hormones andBreast CancerActive, not recruitingNCT067653951 country
- Serratus Posterior Superior Interfascial Plane Block for Breast SurgeryCompletedNCT05972083Not applicable1 country
- Ultrasound Guided Erector Spinae Plane BlockCompletedNCT06657092Not applicable1 country
- Radiomics Model Based on DCE-MRI and Ultrasound Images for Breast Lesion ClassificationCompletedNCT064970231 country
- Using Deep Learning and Radiomics to Diagnose Benign and Malignant Breast Lesions Based on UltrasoundCompletedNCT060699211 country