Drug
Lisdexamfetamine clinical trials
Also written Vyvanse, SPD489 and NRP104.
Includes 1 study of Lisdexamfetamine sulfate.
Keep track of what changes. Save the lisdexamfetamine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
97 studies that test it; most in 2009 (13)
| Year | Studies |
|---|---|
| 2004 | 2 |
| 2005 | 1 |
| 2006 | 3 |
| 2007 | 3 |
| 2008 | 11 |
| 2009 | 13 |
| 2010 | 11 |
| 2011 | 12 |
| 2012 | 9 |
| 2013 | 7 |
| 2014 | 4 |
| 2015 | 6 |
| 2017 | 4 |
| 2018 | 4 |
| 2019 | 3 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 48 · Other 49
Shire (40) · New River Pharmaceuticals (6) · University of Pennsylvania (5) · New York State Psychiatric Institute (4) · Lindner Center of HOPE (4) · University of Minnesota (3) · Yale University (3) · Duke University (3)
Often tested with
Tested in the same studies.
Methylphenidate (4) · Guanfacine (3) · Adderall (2) · LDX 50 (1) · LDX 70 (1) · Behavioral Intervention (1) · Estradiol (1)
Related medicines
As reviewed, each with the page that says it.
Studies
Open first, then newest update. How each study uses lisdexamfetamine is read from its arms, and is right about nine times in ten.
Testing it · 97
- Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 DiabetesRecruitingPhase 2Medical University of LodzNCT05957055Written as Lisdexamfetamine
- Experimental fMRI Study of Guanfacine and Lisdexamfetamine in ADHD AdolescentsCompletedNot applicableKing's College LondonNCT03333668Written as Lisdexamfetamine dimesylate
- Vyvanse in Children Aged 6 to 12 YearsCompletedEarly Phase 1University of MinnesotaNCT05416125Written as Lisdexamfetamine Dimesylate
- Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)CompletedPhase 2/3Yale UniversityNCT04599504Written as Lisdexamfetamine Dimesylate (Medication)
- Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance TreatmentCompletedPhase 3Yale UniversityNCT03926052Written as Lisdexamfetamine Dimesylate
- Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue SyndromeCompletedPhase 4Rochester Center for Behavioral MedicineNCT01071044Written as Lisdexamfetamine Dimesylate
- To Compare and Evaluate the Oral Bioavailability of Lisdexamfetamine 70 mg Capsule With That of Elvanse® 70 mg Capsules, Hard Lisdexamfetamine Dimesylate in Healthy, Adult, Human Subjects Under Fasting Conditions.CompletedPhase 1Humanis Saglık Anonim SirketiNCT07098585Written as Lisdexamfetamine capsule
- Effects of LDX on Functioning of College Students With ADHDCompletedPhase 4University of Rhode IslandNCT01342445Written as lisdexamfetamine dimesylate
- Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute TreatmentCompletedPhase 3Yale UniversityNCT03924193Written as Lisdexamfetamine Dimesylate
- Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With ADHD and AutismCompletedPhase 4JPM van Stralen Medicine ProfessionalNCT03337646Written as Lisdexamfetamine Dimesylate
- IMProving Executive Function StudyCompletedPhase 4University of PennsylvaniaNCT03187353Written as Lisdexamfetamine
- An fMRI Study of Stimulant vs. Non-Stimulant Treatment of ADHDTerminatedNot applicableNew York State Psychiatric InstituteNCT02259517Written as Lisdexamfetamine
- Study of Lisdexamfetamine Sulfate to Treat Cognitive Dysfunction in Multiple SclerosisCompletedPhase 2State University of New York at BuffaloNCT01615887Written as lisdexamfetamine sulfate
- Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHDCompletedNot applicableNew York State Psychiatric InstituteNCT01415440Written as Lisdexamfetamine
- Dose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesylate) in Children Aged 6-12 Diagnosed With ADHDCompletedPhase 4ShireNCT00500071Written as Vyvanse (lisdexamfetamine dimesylate)
- Shire SCT: Lisdexamfetamine Treatment for ADHD and SCTCompletedPhase 2NYU Langone HealthNCT02635035Written as Lisdexamfetamine
- SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating DisorderCompletedPhase 3ShireNCT01718509Written as SPD489 (Lisdexamfetamine dimesylate)
- Efficacy of Lisdexamfetamine Dimesylate for Promoting Occupational Success in Young Adults With ADHDCompletedPhase 4Gregory FabianoNCT03446885Written as Lisdexamfetamine Dimesylate 40 MG
- Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity DisorderCompletedPhase 4ShireNCT00877487Written as SPD489 (Lisdexamfetamine dimesylate)
- SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of SchizophreniaTerminatedPhase 3ShireNCT01760889Written as SPD489 low dose range (40mg, 80mg, and 100mg)
See all 97 studies that test lisdexamfetamine →
Given in every arm · 2 — lisdexamfetamine is usual care beside what is tested
- A Trial to Assess How Centanafadine Interacts With Stimulants in the BodyCompletedPhase 1Otsuka Pharmaceutical Development & Commercialization, Inc.NCT07314333Written as Lisdexamfetamine
- Characterization and Sequential Pharmacotherapy of Severe Mood DysregulationCompletedPhase 2University of California, Los AngelesNCT01714310Written as lisdexamfetamine
As the comparator · 3 — what is tested is compared with lisdexamfetamine
- Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating DisorderRecruitingPhase 2Johns Hopkins UniversityNCT06847399Written as Lisdexamfetamine Dimesylate
- A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant UsersCompletedPhase 1Otsuka Pharmaceutical Development & Commercialization, Inc.NCT02144415Written as lisdexamfetamine 150 mg
- Real World Evidence of the Efficacy and Safety of FOQUESTCompletedPhase 4Purdue Pharma, CanadaNCT04152629Written as Lisdexamfetamine Dimesylate
Codes
What other systems call lisdexamfetamine · ClinicalTrials.gg INT006599
- MeSH (NLM) D000069478Lisdexamfetamine DimesylateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) H645GUL8KJLISDEXAMFETAMINEConfirmed FDA, NLM, Wikidata
- RxNorm 700810Confirmed FDA, Wikidata
- Wikidata Q6558704lisdexamfetamineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C75114LisdexamfetamineOne source FDA
- DrugBank DB01255One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069478 | Lisdexamfetamine Dimesylate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | H645GUL8KJ | LISDEXAMFETAMINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 700810 | — | Confirmed FDA, Wikidata |
| Wikidata | Q6558704 | lisdexamfetamine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C75114 | Lisdexamfetamine | One source FDA |
| DrugBank | DB01255 | — | One source Wikidata |
Also registered as lisdexamfetamine dimesylate (UNII SJT761GEGS · RxNorm 673579).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.