Drug
Aliskiren clinical trials
Also written Tekturna, Rasilez and SPP100.
- studies test it
- 132
- open now
- 1
- in phase 3
- 47
- first study started
- 2001
Keep track of what changes. Save the aliskiren studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
132 studies that test it; most in 2009 (29)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2004 | 7 |
| 2005 | 18 |
| 2006 | 10 |
| 2007 | 7 |
| 2008 | 18 |
| 2009 | 29 |
| 2010 | 26 |
| 2011 | 9 |
| 2012 | 3 |
| 2013 | 2 |
| 2015 | 1 |
| 2020 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 19
- Phase 3
- 47
- Phase 4
- 49
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 81 · Other 51
Novartis (59) · Novartis Pharmaceuticals (21) · Medical University of Gdansk (3) · Vanderbilt University Medical Center (2) · Texas Tech University Health Sciences Center (2) · The University of Hong Kong (2) · UMC Utrecht (2) · Brigham and Women's Hospital (2)
Often tested with
Tested in the same studies.
Hydrochlorothiazide (13) · Amlodipine (11) · Valsartan (7) · Losartan (4) · Eplerenone (3) · Metoprolol (2) · Enalapril (2) · Ramipril (2)
Studies
Open first, then newest update. How each study uses aliskiren is read from its arms, and is right about nine times in ten.
Testing it · 132
- Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 GlomerulopathyRecruitingPhase 2Region SkaneNCT04183101Written as Aliskiren
- A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential HypertensionCompletedPhase 3NovartisNCT00667719Written as Aliskiren
- Effect of Light Meal on Pharmacokinetic and Pharmacodynamics of Aliskiren in Patients With Mild to Moderate HypertensionCompletedPhase 1Novartis PharmaceuticalsNCT00933920Written as Aliskiren
- Pharmacokinetic and Pharmacodynamic Profiles of Aliskiren in Japanese Patients With Mild to Moderate Essential HypertensionCompletedPhase 1NovartisNCT00424541Written as SPP100 (aliskiren)
- Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate HypertensionCompletedPhase 4NovartisNCT00765947Written as Aliskiren
- Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With HypertensionCompletedPhase 4Centre Hospitalier Universitaire VaudoisNCT01519635Written as Aliskiren
- A Clinical Study to Evaluate Safety & Efficacy of the Combination of Aliskiren, Valsartan & Hydrochlorothiazide in Diabetic Hypertensive Nonresponder PatientsCompletedPhase 3NovartisNCT00219102Written as aliskiren
- Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection FractionCompletedPhase 4Wake Forest University Health SciencesNCT00982033Written as aliskiren
- Aldosterone and the Metabolic SyndromeCompletedPhase 1Vanderbilt University Medical CenterNCT01103245Written as Aliskiren 150 mg (ALI 150)
- Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac TransplantationTerminatedPhase 4University of Colorado, DenverNCT01235910Written as Aliskiren
- Vitamin D Deficiency in Patients With HypertensionTerminatedPhase 4UConn HealthNCT00974922Written as Aliskiren
- Shiga Microalbuminuria Reduction Trial-2CompletedPhase 4Shiga UniversityNCT01461499Written as Aliskiren
- Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic ComplianceTerminatedNot applicableBrigham and Women's HospitalNCT01252238Written as Aliskiren
- Aliskiren on Retinal Vasculature Treatment StudyCompletedPhase 3University of Erlangen-Nürnberg Medical SchoolNCT01318395Written as Aliskiren
- Direct Renin Inhibition Effects on Atherosclerotic BiomarkersCompletedPhase 4Texas Tech University Health Sciences CenterNCT00818779Written as Aliskiren
- Treatment of Supine Hypertension in Autonomic FailureCompletedPhase 1Vanderbilt UniversityNCT00223717Written as aliskiren
- Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II DiabeticsWithdrawnPhase 4William Beaumont HospitalsNCT00994253Written as Aliskiren
- The Effects of Renin Inhibition on Fibrinolytic Balance and Endothelial FunctionCompletedPhase 4Vanderbilt University Medical CenterNCT03115853Written as Aliskiren 150 mg
- Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFSCompletedPhase 3Samsung Medical CenterNCT01715207Written as Aliskiren
- A Clinical Study to Evaluate the Safety and Efficacy of the Combination of Aliskiren and Amlodipine in Hypertensive Non Responders PatientsCompletedPhase 3NovartisNCT00219076Written as aliskiren
See all 132 studies that test aliskiren →
Given in every arm · 3 — aliskiren is usual care beside what is tested
- A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide.CompletedPhase 3NovartisNCT00386607Written as Aliskiren
- Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic HypertensionCompletedPhase 4NovartisNCT00797316Written as Aliskiren
- An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood PressureCompletedPhase 3NovartisNCT00402103Written as Aliskiren
As the comparator · 5 — what is tested is compared with aliskiren
- Direct Renin Inhibition and the KidneyCompletedPhase 1Vitae Pharmaceuticals, Inc.NCT01217736Written as aliskiren
- Efficacy and Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential HypertensionCompletedPhase 3NovartisNCT01237223Written as Aliskiren 150 mg
- Study to Evaluate the Efficacy and Safety of Combination Aliskiren/Amlodipine in Patients Not Adequately Responding to Aliskiren AloneCompletedPhase 3NovartisNCT00777946Written as Aliskiren 300 mg
- Aliskiren/Amlodipine/Hydrochlorothiazide (HCTZ) Versus Aliskiren/Amlodipine in US Minority Patients With Stage II Systolic HypertensionCompletedPhase 4NovartisNCT00942994Written as Aliskiren/Amlodipine
- Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II HypertensionCompletedPhase 3NovartisNCT00705575Written as Aliskiren (300 mg)
Codes
What other systems call aliskiren · ClinicalTrials.gg INT004415
- MeSH (NLM) C446481aliskirenConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 502FWN4Q32ALISKIRENConfirmed FDA, NLM, Wikidata
- RxNorm 325646Confirmed FDA, Wikidata
- Wikidata Q414904aliskirenConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C65222AliskirenOne source FDA
- DrugBank DB09026One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C446481 | aliskiren | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 502FWN4Q32 | ALISKIREN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 325646 | — | Confirmed FDA, Wikidata |
| Wikidata | Q414904 | aliskiren | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C65222 | Aliskiren | One source FDA |
| DrugBank | DB09026 | — | One source Wikidata |
Also registered as aliskiren hemifumarate (UNII C8A0P8G029 · RxNorm 732498).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.