Glomerulonephritis, IGA clinical trials
The registry lists 275 studies for Glomerulonephritis, IGA across more than 10 countries. 107 are recruiting or about to start. 239 of them are mainly about Glomerulonephritis, IGA (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Novartis Pharmaceuticals (18) · Guangdong Provincial People's Hospital (7) · Sun Yat-sen University (7) · Otsuka Pharmaceutical Development & Commercialization, Inc. (6) · Travere Therapeutics, Inc. (5) · Chengdu Suncadia Medicine Co., Ltd. (5) · Peking University First Hospital (5) · The Children's Hospital of Zhejiang University School of Medicine (5)
What is being tested here
Drugs under test in Glomerulonephritis, IGA studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Telitacicept | 4 | 4 | 8 |
| Atrasentan | 3 | 3 | 6 |
| Iptacopan | 3 | 3 | 5 |
| Prednisolone | 3 | 2 | 5 |
| Mycophenolic Acid | 2 | 2 | 11 |
| Sibeprenlimab | 2 | 3 | 5 |
| TACI receptor-IgG Fc fragment fusion protein | 2 | 1 | 5 |
| Sparsentan | 2 | 1 | 5 |
| Povetacicept | 2 | 3 | 4 |
| Zigakibart | 2 | 2 | 4 |
Drug classes tested here Endothelin receptor antagonists 6 open · Corticosteroids 4 open · Angiotensin receptor blockers (ARBs) 3 open · Antimetabolites 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria · Phase 3 · Biocity Biopharmaceutics Co., Ltd.
- May 2027A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN) · Phase 3 · Biogen
- Jun 2027Clinical Study on the Efficacy and Safety of Telitacicept in the Treatment of Pediatric IgA Nephropathy or IgA Vasculitis Nephritis · Phase 3 · Guixia Ding
- Aug 2027A Study of Zigakibart in Adults With IgA Nephropathy · Phase 3 · Novartis Pharmaceuticals
- Oct 2027A Trial of HRS-5965 Capsule in Primary IgA Nephropathy · Phase 3 · Chengdu Suncadia Medicine Co., Ltd.
- Nov 2026IgA Nephropathy Biomarkers Evaluation Study (INTEREST) · Sun Yat-sen University
- Dec 2026A Food-Effect Study of Budesonide Delayed Release Tablet (D23A) in Healthy Chinese Participants · Triastek, lnc.
- Dec 2026The Randomized Controlled Study of Shenqi Yishen Granules in the Treatment of IgA Nephropathy · Keda Lu
- Dec 2026Efficacy and Safety of Telitacicept in IgAN · Ruijin Hospital
- Dec 2026A Study of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment · Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd.
Who these studies take
Of the 67 Glomerulonephritis, IGA studies recruiting now, 39 (58%) set no upper age limit and 23 (34%) stop at 75 or younger. 20 (30%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 16 (24%) | 16 (24%) |
| 18 | 66 (99%) | 66 (99%) |
| 30 | 62 (93%) | 62 (93%) |
| 40 | 62 (93%) | 62 (93%) |
| 50 | 61 (91%) | 61 (91%) |
| 65 | 59 (88%) | 59 (88%) |
| 75 | 54 (81%) | 54 (81%) |
| 85 | 43 (64%) | 43 (64%) |
Across all 275 studies, recruiting or not: 48% stop at 75 or younger and 25% at 65; 18% take children; <1% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Glomerulonephritis, IGA studies take
Of 41 phase 2 interventional studies under Glomerulonephritis, IGA, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 11 mo4–13 · 22 studies | — | — |
| Phase 2 | 33 mo17–50 · 41 studies | — | — |
| Phase 3 | 55 mo39–70 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting3
- Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat GlomerulonephritisNov 3, 2026NCT05517980
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyNov 3, 2026NCT07902817
- A Study to Evaluate the Effect of ARGX-121 on the Change in Proteinuria in Adult Participants With IgANOct 27, 2026NCT07773727
Results posted1
- Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy PatientsNov 4, 2026NCT04578834
Newly registered8
- A Pharmacokinetic Study of Budesonide Delayed Release Tablet D23A (D23) in Healthy Chinese Participants Under Fasting ConditionsNov 9, 2026NCT07925216
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyOct 29, 2026NCT07902817
- MYTP01 for Immune-Mediated DiseasesOct 28, 2026NCT07901764
- A Food-Effect Study of Budesonide Delayed Release Tablet (D23A) in Healthy Chinese ParticipantsOct 27, 2026NCT07897240
- Efficacy and Safety of Obinutuzumab Beta in Primary IgA Nephropathy With Active Pathological LesionsOct 22, 2026NCT07888335
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- A Study to Learn About the Effects of Felzartamab on the Kidneys of Adults With Immunoglobulin A Nephropathy (IgAN)Oct 22, 2026NCT07889362
- A Phase 3b Study of Participant Experience on Povetacicept Administered Via Autoinjector as Compared to Sibeprenlimab Administered Via Prefilled SyringeOct 22, 2026NCT07890909
- IBI3034 Study in Healthy Adults and Patients With Primary IgA NephropathyOct 21, 2026NCT07886476
Studies
Recruiting first, then most recently updated. Showing 50 of 275. Browse all 275 → or search them.
- Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgANRecruitingNCT07498335Phase 38 countries
- MYTP01 for Immune-Mediated DiseasesNot yet recruitingNCT07901764Not applicable1 country
- Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of KP104 to Treat GlomerulonephritisRecruitingNCT05517980Phase 21 country
- A Phase 3 Blinded Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07902817Phase 31 country
- A Study of JADE101 in Participants With Immunoglobulin A NephropathyRecruitingNCT07541287Phase 25 countries
- A Study to Evaluate the Effect of ARGX-121 on the Change in Proteinuria in Adult Participants With IgANRecruitingNCT07773727Phase 22 countries
- A Food-Effect Study of Budesonide Delayed Release Tablet (D23A) in Healthy Chinese ParticipantsNot yet recruitingNCT07897240Phase 11 country
- A Phase 3b Study of Participant Experience on Povetacicept Administered Via Autoinjector as Compared to Sibeprenlimab Administered Via Prefilled SyringeNot yet recruitingNCT07890909Phase 3
- A Study to Learn About the Effects of Felzartamab on the Kidneys of Adults With Immunoglobulin A Nephropathy (IgAN)Not yet recruitingNCT07889362Phase 2
- Efficacy and Safety of Obinutuzumab Beta in Primary IgA Nephropathy With Active Pathological LesionsNot yet recruitingNCT07888335Phase 41 country
- IBI3034 Study in Healthy Adults and Patients With Primary IgA NephropathyNot yet recruitingNCT07886476Phase 11 country
- A Study to Assess the Effects of Zigakibart on IgA Nephropathy.RecruitingNCT07146906Phase 211 countries
- Phase 2 Study of ADX-038 in Complement-Mediated Kidney DiseaseRecruitingNCT06989359Phase 28 countries
- Mediators of Loin Pain in IgA NephropathyEnrolling by invitationNCT076495381 country
- A Phase 3 Open-Label Study of Long-term Treatment With Povetacicept in Adults With Immunoglobulin A NephropathyEnrolling by invitationNCT07807995Phase 31 country
- Trial of Sibeprenlimab in Children and Adolescents With Immunoglobulin A Nephropathy (IgAN)Not yet recruitingNCT07770815Phase 3
- A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)RecruitingNCT06935357Phase 328 countries
- Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN StudyRecruitingNCT06350630Phase 21 country
- Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)RecruitingNCT06676579Phase 21 country
- A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA NephropathyRecruitingNCT04557462Phase 336 countries
- A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3GRecruitingNCT06419205Phase 22 countries
- A Study of the Efficacy and Safety of Zigakibart + Atrasentan in Adult Patients With Primary IgA NephropathyNot yet recruitingNCT07850752Phase 3
- Mechanistic Evaluation of Atrasentan in Patients With IgA Nephropathy (IgAN)Not yet recruitingNCT07820995Phase 41 country
- To Assess the Efficacy and Safety of Utilizing Galactose-deficient IgA1 Biomarker Changes to Guide Pathogenic IgA-targeted Therapeutic StrategiesRecruitingNCT07822100Not applicable1 country
- IgA Nephropathy Registration Initiative of High Quality (INSIGHT)RecruitingNCT030019471 country
- Correlation of Microbiome and Metabonomics With IgA NephropathyRecruitingNCT051908481 country
- A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney DiseasesNot yet recruitingNCT07389499Early Phase 11 country
- Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgANRecruitingNCT06994845Phase 38 countries
- Chinese Adults With Kidney DiseaseRecruitingNCT07522099Phase 21 country
- Efficacy and Safety of Nefecon on Prevention of Relapse of IgA NephropathyRecruitingNCT07604311Phase 41 country
- Efficacy and Safety of Mycophenolate Mofetil in Refractory IgA NephropathyNot yet recruitingNCT07785128Phase 21 country
- Study of the Link Between Complement Activation and IgA Nephropathy SeverityRecruitingNCT052344631 country
- The Chinese Registry of Prognostic Study of IgA Nephropathy (CRPIGA)RecruitingNCT048587241 country
- Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.RecruitingNCT06858319Phase 39 countries
- Universal STAR-T Cell Injection in Autoimmune Kidney DiseasesNot yet recruitingNCT07746453Not applicable1 country
- The MIMIGA Study is a Randomized, Double-blind, Placebo-controlled Crossover Trial Evaluating the Safety and Efficacy of SCFA vs. Placebo. Administered Orally Once Daily With Standard Care, it Aims to Prevent CKD Progression in Biopsy-proven IgA Nephropathy by Modulating the Gut Microbiome.Enrolling by invitationNCT07750249Early Phase 11 country
- Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of EVER001 in Participants With Selected Proteinuric Glomerular DiseasesRecruitingNCT07614477Phase 21 country
- A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.RecruitingNCT07203404Early Phase 11 country
- Study of WAL0921 in Patients With Glomerular Kidney DiseasesRecruitingNCT06466135Phase 27 countries
- Study of Ravulizumab in Pediatric Participants With Primary IgANRecruitingNCT07024563Phase 37 countries
- Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgANRecruitingNCT06797518Phase 25 countries
- Phase II Clinical Study on the Efficacy and Safety of QLS7305 in Patients With Kidney Disease (Part A)Not yet recruitingNCT07730632Phase 21 country
- A Trial to Evaluate the Long-term Safety and Tolerability of HRS-5965 in Patients With Primary IgA NephropathyRecruitingNCT07582133Phase 21 country
- Epithelial Dysmetabolism and Renal Fibrosis in ANCA VasculitisRecruitingNCT070102501 country
- RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune DiseasesNot yet recruitingNCT07674147Early Phase 11 country
- Atacicept in Multiple Glomerular DiseasesRecruitingNCT06983028Phase 21 country
- Study of BHV-1400 in IgA NephropathyRecruitingNCT07054684Phase 12 countries
- RESistance of IgA Nephropathy to Conventional and Newly-approved Therapies: an Observational, Real-life Study (RESIGAN)RecruitingNCT069262441 country
- A Rollover Study to Evaluate the Long-Term Safety and Efficacy of AtaciceptEnrolling by invitationNCT06674577Phase 21 country
- A Study to Determine if BHV-1400 is Effective and Safe in Adults With IgA NephropathyNot yet recruitingNCT07642050Phase 3