Drug
Enalapril clinical trials
Also written Vasotec and Renitec.
- studies test it
- 68
- open now
- 8
- in phase 3
- 18
- first study started
- 1992
Keep track of what changes. Save the Enalapril studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Combined with it in one product
Studies by the year they started
66 studies that test it; most in 2009 (6)
| Year | Studies |
|---|---|
| 1992 | 1 |
| 1994 | 1 |
| 1997 | 1 |
| 2000 | 3 |
| 2003 | 3 |
| 2004 | 1 |
| 2005 | 4 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 4 |
| 2009 | 6 |
| 2010 | 6 |
| 2011 | 1 |
| 2012 | 4 |
| 2013 | 3 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 5 |
| 2018 | 2 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 2 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 7
- Phase 2
- 15
- Phase 3
- 18
- Phase 4
- 21
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 13 · Other 55
Novartis Pharmaceuticals (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Shenzhen Ausa Pharmed Co.,Ltd (3) · European Institute of Oncology (2) · Brigham and Women's Hospital (2) · University of Alberta (2) · National Center for Research Resources (NCRR) (2) · Chulalongkorn University (2)
Often tested with
Tested in the same studies.
Valsartan (6) · Folic Acid (5) · Lisinopril (5) · Losartan (5) · Labetalol (3) · Hydralazine (3) · Sacubitril valsartan sodium hydrate (3) · Sacubitril valsartan (3)
Studies
Open first, then newest update. How each study uses Enalapril is read from its arms, and is right about nine times in ten.
Testing it · 68
- Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)Enrolling by invitationPhase 4Baylor Research InstituteNCT07547878Written as Enalapril
- Cardiovascular Protection After Preeclampsia With EnalaprilRecruitingPhase 3Women and Infants Hospital of Rhode IslandNCT07222852Written as Enalapril
- Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension StudyRecruitingNot applicableThe Cleveland ClinicNCT07363343Written as Nifedipine and Enalapril
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Enalapril
- Postpartum Evaluation of Nifedipine and Enalapril for HypertensionRecruitingPhase 4Nebraska Methodist Health SystemNCT07023003Written as Enalapril 10mg QD
- A Study of Enalapril in Treatment of Venous MalformationsRecruitingPhase 2Oslo University HospitalNCT06788314Written as Enalapril
- Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.RecruitingPhase 3University of Sao Paulo General HospitalNCT04853758Written as Enalapril
- Treatment of Patients With Diabetic Kidney DiseaseNot yet recruitingNot applicableAssiut UniversityNCT06187493Written as lisinopril, enalapril
- Genetic Determinants of ACEI Prodrug ActivationCompletedPhase 4University of MichiganNCT03051282Written as Enalapril
- The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial IITerminatedPhase 2University of AlbertaNCT02281838Written as labetalol/hydralazine/enalapril
- PROACT: Can we Prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma?CompletedPhase 3South Tees Hospitals NHS Foundation TrustNCT03265574Written as Enalapril
- Prevention of Diabetes and HypertensionTerminatedPhase 4Istituto Auxologico ItalianoNCT00456963Written as enalapril tablets
- Blood Pressure Management in Stroke Following Endovascular TreatmentCompletedPhase 2Hamilton Health Sciences CorporationNCT04484350Written as Enalapril
- Prevention of Anthracycline-induced CardiotoxicityActive, not recruitingPhase 3European Institute of OncologyNCT01968200Written as Enalapril
- Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart FailureCompletedPhase 2/3Novartis PharmaceuticalsNCT02678312Written as Enalapril
- Medicine-induced Cardiac Hemodialysis on COVID-19CompletedPhase 4Yang I. PachankisNCT05711810Written as Enalapril Maleate 10Mg Tab
- Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum PeriodCompletedPhase 4Brigham and Women's HospitalNCT04236258Written as Enalapril
- Reduction of Night-time Blood Pressure in Pediatric Renal Transplant RecipientsCompletedPhase 2/3Northwell HealthNCT01007994Written as New Medication: Enalapril, Isradipine, Propranolol
- Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsiaCompletedPhase 2Manchester University NHS Foundation TrustNCT03466333Written as Enalapril Maleate
- Impact of Angiotensin Converting Enzyme Activity on Exercise Training SensitivityCompletedNot applicableUniversity of CopenhagenNCT03949075Written as Enalapril
See all 68 studies that test Enalapril →
Given in every arm · 1 — Enalapril is usual care beside what is tested
As the comparator · 22 — what is tested is compared with Enalapril
- Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 GlomerulopathyRecruitingPhase 2Region SkaneNCT04183101Written as Enalapril
- Pulmonary REsistance Modification Under Treatment With Sacubitril/valsartaN in paTients With Heart Failure With Reduced Ejection FractionRecruitingPhase 4Clinical Hospital Heliodor Swiecicki of the Medical University of Karol Marcinkowski in PoznańNCT05487261Written as Enalapril
- The Effects of Sacubitril-Valsartan vs Enalapril on Left Ventricular Remodeling in ST-elevation Myocardial InfarctionNot yet recruitingPhase 3West China HospitalNCT04912167Written as Enalapril
- Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCCCompletedPhase 4Novartis PharmaceuticalsNCT04023227Written as Enalapril
- An Extension Study Designed to Assess Effects of Losartan on Proteinuria in Pediatric Populations (MK-0954-326 AM1,EXT1(AM2))CompletedPhase 3Organon and CoNCT00568178Written as Enalapril Maleate
- COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart FailureCompletedPhase 3Novartis PharmaceuticalsNCT03917459Written as Enalapril
- Study of Efficacy and Safety of LCZ696 in Japanese Patients With Chronic Heart Failure and Reduced Ejection FractionCompletedPhase 3Novartis PharmaceuticalsNCT02468232Written as Enalapril
- Comparison Between the Efficacy of SGLT2 Inhibitor Therapy Versus ACE Inhibitor in the Treatment of Diabetic Kidney DiseaseStatus unknownPhase 2/3Omar Tarek ElfarargiNCT05373004Written as Enalapril Maleate 20 mg
- A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF PatientsCompletedPhase 3Novartis PharmaceuticalsNCT03066804Written as Enalapril
- Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.CompletedPhase 4Novartis PharmaceuticalsNCT02768298Written as Enalapril
- Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.CompletedPhase 4Novartis PharmaceuticalsNCT02970669Written as enalapril
- Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection FractionCompletedPhase 4Novartis PharmaceuticalsNCT02874794Written as Enalapril
- Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.CompletedPhase 4Novartis PharmaceuticalsNCT02554890Written as Enalapril
- The Effect of Neprilysin (LCZ696) on Exercise Tolerance in Patients With Heart FailureCompletedPhase 4University of Sao Paulo General HospitalNCT03190304Written as Enalapril
- randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart FailureCompletedPhase 3Novartis PharmaceuticalsNCT02900378Written as Enalapril
- Angiotensin-II Receptor Antibodies Blockade With Losartan in Patients With Lupus NephritisStatus unknownNot applicableInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranNCT03526042Written as Enalapril
- This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart FailureTerminatedPhase 3Novartis PharmaceuticalsNCT01035255Written as Enalapril 10 mg BID
- An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of AgeCompletedPhase 3Novartis PharmaceuticalsNCT01151410Written as Enalapril
- A Study to Determine the Effectiveness and Tolerability of MK8141 in Patients With High Blood Pressure (MK-8141-006)CompletedPhase 2Merck Sharp & Dohme LLCNCT00543413Written as Enalapril
- A Study to Investigate the Efficacy and Safety of Different Doses of Losartan Potassium (MK0954-011)CompletedPhase 3Merck Sharp & Dohme LLCNCT00882440Written as Enalapril
Showing 20 of 22.
Codes
What other systems call Enalapril · ClinicalTrials.gg INT007420
- MeSH (NLM) D004656EnalaprilConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 69PN84IO1AENALAPRILConfirmed FDA, NLM, Wikidata
- RxNorm 3827Confirmed FDA, Wikidata
- Wikidata Q422185enalaprilConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62027EnalaprilOne source FDA
- DrugBank DB00584One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004656 | Enalapril | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 69PN84IO1A | ENALAPRIL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3827 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422185 | enalapril | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62027 | Enalapril | One source FDA |
| DrugBank | DB00584 | — | One source Wikidata |
Also registered as enalapril maleate (UNII 9O25354EPJ · RxNorm 203123).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.