Tuberculosis, Pulmonary clinical trials
The registry lists 319 studies for Tuberculosis, Pulmonary across more than 10 countries. 71 are recruiting or about to start. 268 of them are mainly about Tuberculosis, Pulmonary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Global Alliance for TB Drug Development (22) · National Institute of Allergy and Infectious Diseases (NIAID) (15) · Michael Hoelscher (9) · Johns Hopkins University (7) · TASK Applied Science (6) · Beijing Chest Hospital (6) · Seoul National University Hospital (6) · Foundation for Innovative New Diagnostics, Switzerland (5)
What is being tested here
Drugs under test in Tuberculosis, Pulmonary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Moxifloxacin | 6 | 8 | 15 |
| Bedaquiline | 5 | 12 | 22 |
| Pyrazinamide | 5 | 5 | 16 |
| Linezolid | 4 | 9 | 15 |
| Rifapentine | 3 | 5 | 8 |
| Sitafloxacin | 3 | 3 | 3 |
| Atorvastatin | 3 | 1 | 3 |
| Rifampin | 2 | 3 | 17 |
| Pretomanid | 2 | 6 | 16 |
| BTZ-043 | 2 | 0 | 5 |
Drug classes tested here Statins 3 open · Beta-lactamase inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Short-course Regimens for the Treatment of Pulmonary Tuberculosis · Phase 3 · Centers for Disease Control and Prevention
- Dec 2026Pragmatic Optimized Rifampicin Trial · Phase 3 · Radboud University Medical Center
- Feb 2027Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis:BDLL Chinese Cohort · Phase 3 · Huashan Hospital
- Sep 2027Shortened Regimen for Drug-susceptible TB in Children · Phase 3 · Johns Hopkins University
- Nov 2026Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis · Gates Medical Research Institute
- Nov 2026Effectiveness of Psychosocial Counseling in Patients With a New Tuberculosis Diagnosis · Universitas Diponegoro
- Nov 2026Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary Tuberculosis · DINA KEUMALA SARI
- Dec 2026Remimazolam for Bronchoscopy in High-Risk Patients · First Affiliated Hospital of Zhejiang University
- Dec 2026ID93+GLA-SE Vaccine Against Tuberculosis in Older Adults Aged 55-74 · Quratis Inc.
- Dec 2026Characterization of Tuberculosis Associated Lung Fibrosis and Respiratory Impairment, and Prevention Using Doxycycline · Makerere University
Who these studies take
Of the 45 Tuberculosis, Pulmonary studies recruiting now, 21 (47%) set no upper age limit and 20 (44%) stop at 75 or younger. 11 (24%) take children under 18. 0 (0%) are for women only and 1 (2%) for men only; 7 (16%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (13%) | 6 (13%) |
| 18 | 38 (84%) | 38 (84%) |
| 30 | 38 (84%) | 39 (87%) |
| 40 | 39 (87%) | 40 (89%) |
| 50 | 38 (84%) | 39 (87%) |
| 65 | 38 (84%) | 38 (84%) |
| 75 | 25 (56%) | 25 (56%) |
| 85 | 23 (51%) | 23 (51%) |
Across all 319 studies, recruiting or not: 42% stop at 75 or younger and 34% at 65; 22% take children; 1% are for women only and 2% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tuberculosis, Pulmonary studies take
Of 43 phase 2 interventional studies under Tuberculosis, Pulmonary, half reached primary completion within 30 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 3 mo2–13 · 13 studies | — | — |
| Phase 2 | 30 mo21–37 · 43 studies | — | 30 mo21–49 · 33 studies |
| Interventional, no phase | 17 mo11–29 · 42 studies | — | 17 mo11–29 · 42 studies |
| Observational | 32 mo21–49 · 44 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisSuspendedNov 2, 2026NCT06192160
Newly registered4
- Vitamin D3 and Monocyte Responses in Pregnant Women With Pulmonary TuberculosisOct 30, 2026NCT07907094
- Effect of Vitamin D and Zinc Supplementation on Inflammatory Biomarkers in Pulmonary Tuberculosis PatientsOct 27, 2026NCT07899138
- BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in ChildrenOct 26, 2026NCT07893444
- Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary TuberculosisOct 21, 2026NCT07887724
Studies
Recruiting first, then most recently updated. Showing 50 of 319. Browse all 319 → or search them.
- Fibroblast Activating Protein (FAP) PET/CT in Adults With TuberculosisRecruitingNCT07830771Early Phase 11 country
- The LalelaLung Study: Digital Stethoscope Clinical EvaluationNot yet recruitingNCT07631377Phase 4
- BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in ChildrenRecruitingNCT07893444Phase 21 country
- Channa Striata and Curcuma Domestica Supplementation in Patients With Active Pulmonary TuberculosisRecruitingNCT07887724Not applicable1 country
- Platform Assessing Regimens and Durations In a Global Multisite Consortium for TBRecruitingNCT06114628Phase 25 countries
- Study of Combinations of Novel Promising Drugs for Pulmonary TuberculosisNot yet recruitingNCT07773610Phase 21 country
- Digital Health Intervention to Improve TPT UptakeRecruitingNCT07313995Not applicable1 country
- Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory TrialRecruitingNCT07118059Phase 21 country
- Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruitingNCT06441006Phase 2/35 countries
- Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TBNot yet recruitingNCT06205589Phase 2
- A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 216 countries
- Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TBRecruitingNCT07672405Phase 22 countries
- Short Course Regimen in Low Risk Active Tuberculosis- a Multicenter, Randomized, Active-controlled, TrialRecruitingNCT06727864Phase 31 country
- A Step Forward for Unraveling the Immune Mechanisms and Tools for Tuberculosis Spectrum ManagementNot yet recruitingNCT07735754
- Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary TuberculosisRecruitingNCT07525427Phase 21 country
- Shortened Regimen for Drug-susceptible TB in ChildrenRecruitingNCT06253715Phase 37 countries
- Effectiveness of Psychosocial Counseling in Patients With a New Tuberculosis DiagnosisNot yet recruitingNCT07703696Not applicable1 country
- Evaluating Urine Isoniazid Testing to Detect Nonadherence to Tuberculosis Medications in IndiaEnrolling by invitationNCT06526221Not applicable1 country
- Artificial Intelligence-driven Tuberculosis Landscape Analysis & Stratification ResearchNot yet recruitingNCT076116951 country
- Short-Course Regimens for DS-PTB in AIDS PatientsNot yet recruitingNCT07608172Not applicable
- Blood Tuberculosis DNA Levels to Monitor Tuberculosis TreatmentRecruitingNCT068456181 country
- 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) in Tuberculosis PatientsRecruitingNCT070772131 country
- Parent Study Name: Pulmonary Rehabilitation to Reduce Post-Tuberculosis Morbidity (TB Pure)RecruitingNCT07164742Not applicable1 country
- AIPH-TB: AI-Optimised Pyrazinamide-Hydroxychloroquine vs Standard RIPE for Drug-Sensitive Pulmonary Tuberculosis - A Phase II RCTNot yet recruitingNCT07467252Phase 21 country
- Remimazolam for Bronchoscopy in High-Risk PatientsRecruitingNCT07395596Phase 41 country
- ATORvastatin in Pulmonary TUBerculosis: a POPulation PharmacoKinetics -PharmacoDynamics Sub-study (ATORTUB popPK-PD)RecruitingNCT07303699Phase 21 country
- Pragmatic Optimized Rifampicin TrialRecruitingNCT06057519Phase 32 countries
- Phase 2 Trial to Evaluate the Safety and Tolerability and Early Bactericidal Activity of RESP30TB in TuberculosisRecruitingNCT07073638Phase 21 country
- Safety and Efficacy of Ear Acupuncture for Antituberculosis Drug-Related Nausea and VomitingRecruitingNCT07271225Not applicable1 country
- Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis:BLMZ Chinese CohortNot yet recruitingNCT07268664Phase 31 country
- A PAN-USR TB Multi-Center TrialRecruitingNCT06905522Phase 31 country
- DoseTB-individualised Dosing by Model-informed Precision Dosing for Pulmonary TuberculosisRecruitingNCT065853581 country
- Plasma MTB cfDNA Before BronchoscopyNot yet recruitingNCT072304571 country
- PanACEA - STEP2C -01RecruitingNCT05807399Phase 26 countries
- ATORvastatin in Pulmonary TUBerculosisRecruitingNCT06199921Phase 21 country
- Evaluation of PATHFAST-LAM as a Tuberculosis Treatment Monitoring Tool in KenyaNot yet recruitingNCT071579041 country
- Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible TuberculosisNot yet recruitingNCT07129629Phase 2
- Evaluating a Shorter, Rifampicin-Based Treatment for People With Less Severe Tuberculosis DiseaseNot yet recruitingNCT07118696Phase 3
- Ultra-Short Regimen for Elderly DS-TBNot yet recruitingNCT07076225Phase 3
- A Phase III Study of Oral Sudapyridine (WX-081) Tablets in Rifampicin-Resistant Pulmonary Tuberculosis PatientsRecruitingNCT05824871Phase 31 country
- ID93+GLA-SE Vaccine Against Tuberculosis in Older Adults Aged 55-74RecruitingNCT06714513Phase 11 country
- Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective StudyNot yet recruitingNCT069229161 country
- Characterization of Tuberculosis Associated Lung Fibrosis and Respiratory Impairment, and Prevention Using DoxycyclineRecruitingNCT06477185Phase 21 country
- Novel Triple-dose Tuberculosis Retreatment RegimenRecruitingNCT04260477Phase 31 country
- Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled BreathRecruitingNCT065284181 country
- A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With EthionamideRecruitingNCT06748937Phase 21 country
- Drug-Drug Interaction and Food Effect of Sudapyridine(WX-081) With Itraconazole and Rifampin in Healthy Chinese AdultsNot yet recruitingNCT06701136Phase 1
- Post TB Sequelae StudyEnrolling by invitationNCT067441791 country
- A Systemic Screening for TB Disease in High-risk Groups in BarcelonaRecruitingNCT067065961 country
- Observation Study on the Efficacy of Yiqi Gubiao Pill in the Treatment of Chronic Obstructive Pulmonary Disease Secondary to Active Pulmonary TuberculosisNot yet recruitingNCT06676800Early Phase 1