An interventional study of CHANA STRIATA AND CURCUMA and Maltodextrin (Placebo) in Pulmonary Tuberculosis, sponsored by DINA KEUMALA SARI. Recruiting at 2 sites in Indonesia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-21.
Sponsored by DINA KEUMALA SARI · Not applicable, Interventional, and Supportive care
This study aims to evaluate the effect of combined supplementation with Channa striata extract and Curcuma domestica rhizome on nutritional status, inflammatory markers, and quality of life in patients with active pulmonary tuberculosis receiving standard anti tuberculosis treatment at public health centers in Medan City. Pulmonary tuberculosis is frequently accompanied by malnutrition, persistent systemic inflammation, and impaired quality of life, all of which can delay recovery and worsen clinical outcomes. Channa striata is a rich source of high quality protein and albumin that may support nutritional recovery, while Curcuma domestica contains curcumin with well documented anti inflammatory properties. This study will assess whether the combined supplementation provides additional benefits in improving nutritional status, reducing inflammatory markers, and enhancing health related quality of life compared with standard treatment alone. The findings are expected to provide evidence for a safe, affordable, and locally available nutritional intervention that may complement conventional tuberculosis management.
340 studies on the registry are indexed under Tuberculosis, Pulmonary; 69 are open to participants now.
This study's planned enrollment of 80 is below the median of 150 across 243 interventional studies indexed under Tuberculosis, Pulmonary.
Browse Tuberculosis, Pulmonary studies →DINA KEUMALA SARI is the lead sponsor of 7 studies on the registry; 6 are open to participants now.
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Exclusion Criteria:
Channa striata 5gr and curcuma domestica rhizoma 250mg
Dietary Supplement: CHANA STRIATA AND CURCUMA
maltodekstrin
Dietary Supplement: Maltodextrin (Placebo)
Channa striata 5gr and curcuma 250mg
Maltodextrin
Interleukin-6 Concentration
Interleukin-6 (IL-6) concentration will be measured in \[serum/plasma\] using \[laboratory assay\] and reported in \[unit\].
Time frame: baseline and 4 weeks
C-Reactive Protein Concentration
C-reactive protein (CRP) concentration will be measured in \[serum/plasma\] using \[laboratory method\] and reported in \[unit\].
Time frame: baseline and 4 weeks
Health-Related Quality of Life Measured Using the EuroQol Five-Dimension Five-Level Questionnaire (EQ-5D-5L) Index
Health-related quality of life will be assessed using the EuroQol Five-Dimension Five-Level questionnaire (EQ-5D-5L). Responses will be converted into an index value using the Indonesian value set. Index values range from -0.865 to 1.000, with higher values indicating better health-related quality of life.
Time frame: baseline and 4 weeks
Body Weight
Body weight will be measured using a digital weighing scale and reported in kilograms (kg).
Time frame: Baseline and week 4
Body Mass Index
Body mass index (BMI) will be calculated as body weight in kilograms divided by height in meters squared and reported in kg/m². Body weight will be measured using \[weighing instrument\], and height will be measured using \[height measurement instrument\].
Time frame: Baseline and week 4
Muscle Mass
Muscle mass will be measured using \[measurement device and method\] and reported in \[kg or %\].
Time frame: Baseline and week 4
Mid-Upper Arm Circumference
Mid-upper arm circumference will be measured using a non-stretchable measuring tape at the midpoint between the acromion and olecranon and reported in centimeters (cm).
Time frame: Baseline and week 4
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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DINA KEUMALA SARI