Drug
Bedaquiline clinical trials
Also written TMC207, Sirturo and R207910.
- studies test it
- 57
- open now
- 11
- in phase 3
- 22
- first study started
- 2005
Keep track of what changes. Save the bedaquiline studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
57 studies that test it; most in 2016 (5)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2007 | 1 |
| 2009 | 4 |
| 2010 | 4 |
| 2011 | 2 |
| 2012 | 1 |
| 2014 | 2 |
| 2015 | 3 |
| 2016 | 5 |
| 2017 | 3 |
| 2018 | 3 |
| 2019 | 2 |
| 2020 | 4 |
| 2021 | 4 |
| 2022 | 5 |
| 2023 | 3 |
| 2024 | 2 |
| 2025 | 5 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 11
- Phase 2
- 33
- Phase 3
- 22
- Phase 4
- 1
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 16 · Other 41
Global Alliance for TB Drug Development (9) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Tibotec BVBA (5) · Janssen Research & Development, LLC (4) · Janssen Infectious Diseases BVBA (3) · Huashan Hospital (2) · Janssen Pharmaceutical K.K. (2) · Médecins Sans Frontières, France (2)
Often tested with
Tested in the same studies.
Linezolid (18) · Pretomanid (14) · Pyrazinamide (13) · Clofazimine (12) · Moxifloxacin (11) · OPC-67683 (10) · Levofloxacin (6) · Rifabutin (3)
Studies
Open first, then newest update. How each study uses bedaquiline is read from its arms, and is right about nine times in ten.
Testing it · 57
- Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TBRecruitingPhase 2/3Johns Hopkins UniversityNCT06568484Written as Bedaquiline
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT06192160Written as Bedaquiline
- Platform Assessing Regimens and Durations In a Global Multisite Consortium for TBRecruitingPhase 2University College, LondonNCT06114628Written as Bedaquiline (B)
- Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in France (FAST-MDR)RecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT07486024Written as Bedaquiline Oral Tablet
- Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruitingPhase 2/3University of California, San FranciscoNCT06441006Written as Bedaquiline
- Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary InfectionEnrolling by invitationPhase 1Vancouver Coastal HealthNCT07228702Written as Bedaquiline (B)
- Finding the Optimal Regimen for Mycobacterium Abscessus TreatmentRecruitingPhase 2/3The University of QueenslandNCT04310930Written as Bedaquiline
- A PAN-USR TB Multi-Center TrialRecruitingPhase 3Shenzhen Third People's HospitalNCT06905522Written as Bedaquiline (B)
- Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible TuberculosisNot yet recruitingPhase 2Shanghai Pulmonary Hospital, Shanghai, ChinaNCT07129629Written as Bedaquiline (B)
- Ultra-Short Regimen for Elderly DS-TBNot yet recruitingPhase 3Shenzhen Third People's HospitalNCT07076225Written as Bedaquiline (B)
- A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in ChinaRecruitingPhase 4Beijing Chest HospitalNCT05306223Written as Bedaquiline
- Short-course Regimens for the Treatment of Pulmonary TuberculosisActive, not recruitingPhase 2/3Centers for Disease Control and PreventionNCT05766267Written as Bedaquiline
- Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents With Pulmonary MDR-TBSuspendedPhase 2Janssen Research & Development, LLCNCT02354014Written as Bedaquiline (TMC207)
- Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult PatientsCompletedPhase 2/3Global Alliance for TB Drug DevelopmentNCT03338621Written as Bedaquiline
- Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TBCompletedPhase 2Otsuka Pharmaceutical Development & Commercialization, Inc.NCT05221502Written as Bedaquiline
- Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TuberculosisActive, not recruitingPhase 2Brigham and Women's HospitalNCT05556746Written as Bedaquiline (BDQ)
- Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIVCompletedPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT02906007Written as Bedaquiline
- Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TBActive, not recruitingPhase 2Boston UniversityNCT03828201Written as Bedaquiline
- Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary TuberculosisCompletedPhase 2GlaxoSmithKlineNCT05382312Written as Bedaquiline
- A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)CompletedPhase 2/3Janssen Pharmaceutical K.K.NCT04630145Written as Bedaquiline
See all 57 studies that test bedaquiline →
Given in every arm · 11 — bedaquiline is usual care beside what is tested
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform TrialNot yet recruitingPhase 2The University of QueenslandNCT07485010Written as bedaquiline
- 6 Months of Bedaquiline(BDQ), Delamanid(DLM), Linezolid(LZD) and Levofloxacin(LFX) in RR-TB Patients in Hubei ProvinceNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07198685Written as bedaquiline
- A Study on the Short-course Treatment Regimen Containing Pretomanid for Drug-resistant TuberculosisNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07126639Written as bedaquiline
- BTZ-043 Dose Evaluation in Combination and SelectionCompletedPhase 2Michael HoelscherNCT05926466Written as Bedaquiline
- Linezolid Dosing Strategies in Drug-Resistant TBCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05007821Written as Bedaquiline 200 mg
- Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary TuberculosisSuspendedPhase 2Gates Medical Research InstituteNCT07517445Written as Bedaquiline, pretomanid, linezolid
- PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE)CompletedPhase 2LigaChem Biosciences, Inc.NCT04550832Written as Bedaquiline, Delamanid, Moxifloxacin
- Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline CohortActive, not recruitingPhase 3Beijing Chest HospitalNCT06081361Written as Bedaquiline
- Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of CareCompletedPhase 3Wits Health Consortium (Pty) LtdNCT04062201Written as Bedaquiline Oral Tablet
- PanACEA Sutezolid Dose-finding and Combination EvaluationCompletedPhase 2Michael HoelscherNCT03959566Written as Bedaquiline, Delamanid, Moxifloxacin
- PRACTECAL-PKPD Sub StudyStatus unknownPhase 2/3Medecins Sans Frontieres, NetherlandsNCT04081077Written as Bedaquiline
As the comparator · 5 — what is tested is compared with bedaquiline
- Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary TuberculosisRecruitingPhase 2Gates Medical Research InstituteNCT07525427Written as Bedaquiline, pretomanid and linezolid
- A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary TuberculosisRecruitingPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT07209761Written as BPaL
- A Phase III Study of Oral Sudapyridine (WX-081) Tablets in Rifampicin-Resistant Pulmonary Tuberculosis PatientsRecruitingPhase 3Shanghai Jiatan Pharmatech Co., LtdNCT05824871Written as Bedaquiline
- Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary TuberculosisActive, not recruitingPhase 2Global Alliance for TB Drug DevelopmentNCT06058299Written as Bedaquiline
- Evaluation of Early Bactericidal Activity and Safety in Pulmonary Tuberculosis With WX-081CompletedPhase 2Shanghai Jiatan Pharmatech Co., LtdNCT04608955Written as Bedaquiline
Codes
What other systems call bedaquiline · ClinicalTrials.gg INT004721
- MeSH (NLM) C493870bedaquilineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 78846I289YBEDAQUILINEConfirmed FDA, NLM, Wikidata
- RxNorm 1364504Confirmed FDA, Wikidata
- Wikidata Q1257318bedaquilineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C87658BedaquilineOne source FDA
- DrugBank DB08903One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C493870 | bedaquiline | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 78846I289Y | BEDAQUILINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1364504 | — | Confirmed FDA, Wikidata |
| Wikidata | Q1257318 | bedaquiline | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C87658 | Bedaquiline | One source FDA |
| DrugBank | DB08903 | — | One source Wikidata |
Also registered as bedaquiline fumarate (UNII P04QX2C1A5 · RxNorm 1364503).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.