National Institute of Allergy and Infectious Diseases (NIAID): Tuberculosis, Pulmonary trials

The registry lists 18 Tuberculosis, Pulmonary studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 2 are open to participants now and 7 have results posted.

Phase 1 2Phase 2 12Phase 3 1No phase 4(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 2
• Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingNCT06192160Phase 2
• Linezolid Dosing Strategies in Drug-Resistant TBCompletedNCT05007821Phase 2Results posted
• StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With TuberculosisCompletedNCT03882177Phase 2Results posted
• Using Biomarkers to Predict TB Treatment DurationCompletedNCT02821832Phase 2Results posted
• Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary TuberculosisCompletedNCT02583048Phase 2Results posted
• Linezolid to Treat Extensively-Drug Resistant TuberculosisCompletedNCT00727844Phase 2Results posted
• Metronidazole for Pulmonary Tuberculosis (South Korea)CompletedNCT00425113Phase 2Results posted
• Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary TuberculosisCompletedNCT00396084Phase 1/2Results posted
• NexGen EBA Radiologic and Immunologic Biomarkers of Sterilizing Drug Activity in TuberculosisCompletedNCT02371681Phase 2
• Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in MaliTerminatedNCT01381757
• Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary TuberculosisCompletedNCT01301144
• Pimonidazole Hydrochloride to Detect Low Oxygen in Tuberculosis-Infected LungsWithdrawnNCT00374517Phase 2
• Vitamin A Therapy for TuberculosisCompletedNCT00057434Phase 3
• Diagnosing Tuberculosis in HIV Infected Children in PeruCompletedNCT00054769
• Interferon Gamma for Drug Resistant TuberculosisCompletedNCT00001407Phase 2
• A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.CompletedNCT00000796Not applicable
• A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and LevofloxacinCompletedNCT00000778Phase 1