Drug
Linezolid clinical trials
Also written Zyvox.
- studies test it
- 76
- open now
- 19
- in phase 3
- 25
- first study started
- 2001
Keep track of what changes. Save the Linezolid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
75 studies that test it; most in 2025 (7); 1 more planned to start later
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2002 | 3 |
| 2003 | 2 |
| 2004 | 3 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 2 |
| 2011 | 1 |
| 2012 | 4 |
| 2013 | 3 |
| 2014 | 2 |
| 2015 | 3 |
| 2016 | 2 |
| 2017 | 3 |
| 2018 | 3 |
| 2019 | 1 |
| 2020 | 3 |
| 2021 | 5 |
| 2022 | 5 |
| 2023 | 5 |
| 2024 | 4 |
| 2025 | 7 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 26
- Phase 3
- 25
- Phase 4
- 14
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 17 · Other 59
Pfizer (13) · Global Alliance for TB Drug Development (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Boston University (2) · Huashan Hospital (2) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (2) · Médecins Sans Frontières, France (2) · Seoul National University Hospital (2)
Often tested with
Tested in the same studies.
Bedaquiline (18) · Levofloxacin (10) · Clofazimine (9) · Pretomanid (9) · OPC-67683 (7) · Moxifloxacin (7) · Pyrazinamide (6) · Vancomycin (6)
Studies
Open first, then newest update. How each study uses Linezolid is read from its arms, and is right about nine times in ten.
Testing it · 76
- Comprehensive Ambulatory Antibiotics for the Treatment of Congenital SyphilisRecruitingPhase 2London School of Hygiene and Tropical MedicineNCT06921213Written as Linezolid (LZD)
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT06192160Written as Linezolid
- Platform Assessing Regimens and Durations In a Global Multisite Consortium for TBRecruitingPhase 2University College, LondonNCT06114628Written as Linezolid (L)
- Oral Antibiotic Pharmacokinetics in Young InfantsNot yet recruitingPhase 4University of Colorado, DenverNCT07815613Written as Linezolid (LZD)
- Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruitingPhase 2/3University of California, San FranciscoNCT06441006Written as Linezolid
- Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TBRecruitingPhase 2Global Alliance for TB Drug DevelopmentNCT07672405Written as Linezolid
- Linezolid Plus Standard of CareRecruitingNot applicableUniversity Hospital, Basel, SwitzerlandNCT06958835Written as Linezolid 600 mg
- Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective EndocarditisRecruitingPhase 4Fundacion Clinic per a la Recerca BiomédicaNCT05398679Written as Linezolid Oral Tablet
- Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary InfectionEnrolling by invitationPhase 1Vancouver Coastal HealthNCT07228702Written as Linezolid (LZD)
- Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous MeningitisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05383742Written as Linezolid (LZD)
- Finding the Optimal Regimen for Mycobacterium Abscessus TreatmentRecruitingPhase 2/3The University of QueenslandNCT04310930Written as Linezolid
- Linezolid or Vancomycin Surgical Site Infection ProphylaxisRecruitingPhase 4Assistance Publique Hopitaux De MarseilleNCT05571722Written as Linezolid Injection
- Microbiological Characteristics of Biofilm on Double J Ureteral Stents After Lithotripsy.Not yet recruitingPhase 4Menoufia UniversityNCT07301294Written as Linezolid (LZD)
- A PAN-USR TB Multi-Center TrialRecruitingPhase 3Shenzhen Third People's HospitalNCT06905522Written as Linezolid (L)
- Optimizing Linezolid Dosing in Patients With Advanced Renal Impairment: a Therapeutic Drug Monitoring-based EvaluationNot yet recruitingPhase 4Alexandria UniversityNCT07138521Written as Linezolid (IV and PO)
- Ultra-Short Regimen for Elderly DS-TBNot yet recruitingPhase 3Shenzhen Third People's HospitalNCT07076225Written as Linezolid (L)
- Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB)RecruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT05534750Written as Linezolid arm (ZYVOXID®)
- Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric ProphylaxisRecruitingPhase 4Rigshospitalet, DenmarkNCT06709196Written as Linezolid
- Model-informed Precision Dosing for LinezolidNot yet recruitingPhase 3University of Hamburg-EppendorfNCT06444802Written as Linezolid
- Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws)CompletedPhase 3Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la CienciaNCT05764876Written as Linezolid Oral Tablet
See all 76 studies that test Linezolid →
Given in every arm · 15 — Linezolid is usual care beside what is tested
- Study of Combinations of Novel Promising Drugs for Pulmonary TuberculosisNot yet recruitingPhase 2TASK Applied ScienceNCT07773610Written as Linezolid 600Mg Tab
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform TrialNot yet recruitingPhase 2The University of QueenslandNCT07485010Written as linezolid
- 6 Months of Bedaquiline(BDQ), Delamanid(DLM), Linezolid(LZD) and Levofloxacin(LFX) in RR-TB Patients in Hubei ProvinceNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07198685Written as Linezolid (LZD)
- A Study on the Short-course Treatment Regimen Containing Pretomanid for Drug-resistant TuberculosisNot yet recruitingNot applicableWuhan Pulmonary HospitalNCT07126639Written as linezolid
- A Study of an Oral Short-course Regimen Including Bedaquiline for the Treatment of Participants With Multidrug-resistant Tuberculosis in ChinaRecruitingPhase 4Beijing Chest HospitalNCT05306223Written as Linezolid
- Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary TuberculosisSuspendedPhase 2Gates Medical Research InstituteNCT07517445Written as Bedaquiline, pretomanid, linezolid
- Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary TuberculosisCompletedPhase 2GlaxoSmithKlineNCT05382312Written as Linezolid
- PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONINCompletedPhase 2M.D. Anderson Cancer CenterNCT04983901Written as Linezolid
- Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)CompletedPhase 3Merck Sharp & Dohme LLCNCT03583333Written as Linezolid
- Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of CareCompletedPhase 3Wits Health Consortium (Pty) LtdNCT04062201Written as Linezolid Oral Tablet
- Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s)CompletedPhase 2/3Medecins Sans Frontieres, NetherlandsNCT02589782Written as Linezolid
- PRACTECAL-PKPD Sub StudyStatus unknownPhase 2/3Medecins Sans Frontieres, NetherlandsNCT04081077Written as Linezolid
- Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative PathogensCompletedPhase 3ShionogiNCT03032380Written as Linezolid
- Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)CompletedPhase 3Merck Sharp & Dohme LLCNCT02493764Written as Linezolid
- Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With CancerTerminatedPhase 2Forest LaboratoriesNCT02732327Written as Linezolid
As the comparator · 42 — what is tested is compared with Linezolid
- Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)RecruitingPhase 3MicuRxNCT05369052Written as Linezolid (IV and PO)
- Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary TuberculosisRecruitingPhase 2Gates Medical Research InstituteNCT07525427Written as Bedaquiline, pretomanid and linezolid
- A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary TuberculosisRecruitingPhase 3Otsuka Pharmaceutical Development & Commercialization, Inc.NCT07209761Written as BPaL
- Clinical Study on the Early Bactericidal Activity of Contezolid Against Mycobacterium Abscessus DiseaseEnrolling by invitationPhase 2Beijing Chest HospitalNCT07372781Written as linezolid
- Phase II Clinical Study of Contezolid for the Treatment of Tuberculous MeningitisEnrolling by invitationPhase 1/2Beijing Chest HospitalNCT06811025Written as Linezolid (LZD)
- Phase II Clinical Study of Contezolid for the Treatment of Bone and Joint TuberculosisEnrolling by invitationPhase 1/2Beijing Chest HospitalNCT06811012Written as Linezolid (LZD)
- Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to StaphylococcusTerminatedPhase 2Debiopharm International SANCT03723551Written as Linezolid
- Innovating Shorter, All- Oral, Precised, Individualized Treatment Regimen for Rifampicin Resistant Tuberculosis：Contezolid, Delamanid and Bedaquiline CohortActive, not recruitingPhase 3Beijing Chest HospitalNCT06081361Written as Linezolid
- MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure InfectionCompletedPhase 2MicuRxNCT02269319Written as Linezolid
- Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk PatientsTerminatedPhase 4Henry Ford Health SystemNCT01734694Written as Linezolid
- Contezolid Acefosamil Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure InfectionCompletedPhase 2MicuRxNCT03747497Written as linezolid 600 mg
- Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site InfectionsTerminatedPhase 3Menarini GroupNCT04042077Written as Linezolid
- Study the Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)TerminatedPhase 3Paratek Pharmaceuticals IncNCT00865280Written as linezolid
- Study the Efficacy and Safety of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI)CompletedPhase 2Paratek Pharmaceuticals IncNCT03716024Written as Linezolid
- Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial PneumoniaCompletedPhase 3Melinta Therapeutics, Inc.NCT02679573Written as Linezolid
- A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PKCompletedPhase 2LigaChem Biosciences, Inc.NCT02836483Written as Zyvox 600mg, BID
- Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With PneumoniaCompletedPhase 3Nabriva Therapeutics AGNCT02559310Written as Linezolid
- A Study to Assess Objective Endpoint Measurements of Response in Bacterial Skin InfectionsCompletedPhase 2Melinta Therapeutics, Inc.NCT01283581Written as Linezolid
- Tedizolid Phosphate (TR-701 FA, MK-1986) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)CompletedPhase 3Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT02019420Written as Linezolid
- Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure InfectionsCompletedPhase 3Arrevus Inc.NCT02570490Written as linezolid
Showing 20 of 42.
Codes
What other systems call Linezolid · ClinicalTrials.gg INT006573
- MeSH (NLM) D000069349LinezolidConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) ISQ9I6J12JLINEZOLIDConfirmed FDA, NLM, Wikidata
- RxNorm 190376Confirmed FDA, Wikidata
- Wikidata Q411377linezolidConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29158LinezolidOne source FDA
- DrugBank DB00601One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000069349 | Linezolid | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | ISQ9I6J12J | LINEZOLID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 190376 | — | Confirmed FDA, Wikidata |
| Wikidata | Q411377 | linezolid | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29158 | Linezolid | One source FDA |
| DrugBank | DB00601 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.