Drug
Rifampin clinical trials
Also written Rifampicin, Rifadin and Rimactane.
Includes 1 study of Rifampin sodium.
- studies test it
- 278
- open now
- 24
- in phase 3
- 26
- first study started
- 1994
Keep track of what changes. Save the Rifampin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
- HRZE
- 2
Studies by the year they started
276 studies that test it; most in 2011 (22)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 2000 | 1 |
| 2002 | 2 |
| 2003 | 1 |
| 2004 | 2 |
| 2006 | 6 |
| 2007 | 4 |
| 2008 | 9 |
| 2009 | 8 |
| 2010 | 11 |
| 2011 | 22 |
| 2012 | 12 |
| 2013 | 16 |
| 2014 | 16 |
| 2015 | 11 |
| 2016 | 16 |
| 2017 | 14 |
| 2018 | 15 |
| 2019 | 18 |
| 2020 | 20 |
| 2021 | 16 |
| 2022 | 16 |
| 2023 | 11 |
| 2024 | 8 |
| 2025 | 11 |
| 2026 | 9 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 186
- Phase 2
- 30
- Phase 3
- 26
- Phase 4
- 23
- No phase
- 16
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 159 · Other 119
National Institute of Allergy and Infectious Diseases (NIAID) (9) · Bristol-Myers Squibb (9) · Boehringer Ingelheim (8) · AstraZeneca (7) · Millennium Pharmaceuticals, Inc. (7) · Pfizer (7) · Janssen Research & Development, LLC (6) · University of California, San Francisco (5)
Often tested with
Tested in the same studies.
Itraconazole (56) · Isoniazid (28) · Pyrazinamide (20) · Ethambutol (19) · Doxycycline (7) · Levofloxacin (6) · Omeprazole (6) · Clarithromycin (6)
Studies
Open first, then newest update. How each study uses Rifampin is read from its arms, and is right about nine times in ten.
Testing it · 278
- A Drug-Drug Interaction Study of Rifampicin and Oral HRS-8080Not yet recruitingPhase 1Shandong Suncadia Medicine Co., Ltd.NCT07876596Written as Rifampicin
- A Phase I Study of the Interaction of D-2570 With Other Drugs in Healthy AdultsNot yet recruitingPhase 1InventisBio Co., LtdNCT07875842Written as Rifampicin
- Rifampin in CYP24A1-related Hypercalcemia and HypercalciuriaRecruitingPhase 2Children's Hospital of PhiladelphiaNCT03301038Written as Rifampin
- Re-evaluating the Duration in Children of TB TreatmentNot yet recruitingPhase 2University of Wisconsin, MadisonNCT07656012Written as Rifampicin
- A Phase I Clinical Trial to Evaluate Pharmacokinetics of HS-10504Not yet recruitingPhase 1Jiangsu Hansoh Pharmaceutical Co., Ltd.NCT07770217Written as Rifampin
- A Clinical Trial of MK-8527 and Rifampin in Adult Participants With Latent Tuberculosis Infection (MK-8527-019)Not yet recruitingPhase 1Merck Sharp & Dohme LLCNCT07600775Written as Rifampin
- Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose RifampicinRecruitingPhase 1Brigham and Women's HospitalNCT05069688Written as rifampicin
- Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous MeningitisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05383742Written as Rifampicin (RIF)
- Drug-Drug Interaction Study of MDR-001 With Rifampin and Itraconazole in Healthy Adult ParticipantsNot yet recruitingPhase 1MindRank AI LtdNCT07550621Written as Rifampin
- Early Use of Realgar-Indigo Naturalis Formula (RIF) Combined With All-trans Retinoic Acid (ATRA) for Treating Acute Promyelocytic Leukemia (APL).RecruitingPhase 3First Affiliated Hospital Xi'an Jiaotong UniversityNCT07503730Written as RIF
- Mechanical Bowel Preparation With or Without Oral Antibiotics in Left Sided Colorectal Cancer SurgeryEnrolling by invitationNot applicableShaukat Khanum Memorial Cancer Hospital & Research CentreNCT07429760Written as Rifampicin (R)
- Pharmacokinetics of Antituberculosis Drugs in Breastfeeding WomenNot yet recruitingPhase 1McGill University Health Centre/Research Institute of the McGill University Health CentreNCT07069582Written as High dose rifampicin
- An Open-Label Drug Interaction Clinical Study to Evaluate Itraconazole, Rifampin, Midazolam and SIM0270 in Chinese Healthy Adult ParticipantsRecruitingPhase 1Jiangsu Simcere Pharmaceutical Co., Ltd.NCT07357610Written as Rifampin
- Rifampin-combined Antibiotic Therapy for Staphylococcal PJIRecruitingNot applicableFirst Affiliated Hospital of Fujian Medical UniversityNCT07313215Written as Rifampicin (R)
- PanACEA - STEP2C -01RecruitingPhase 2Michael HoelscherNCT05807399Written as Rifampicin
- Novel Interventions and Diagnostic Tests for LeprosyRecruitingNot applicableAnnemieke GelukNCT06222372Written as Rifampin
- Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial)Not yet recruitingPhase 3University College, LondonNCT07163143Written as Rifampicin (R)
- Drug-Drug Interaction and Food Effect of Sudapyridine(WX-081) With Itraconazole and Rifampin in Healthy Chinese AdultsNot yet recruitingPhase 1Shanghai Jiatan Pharmatech Co., LtdNCT06701136Written as Rifampin
- Drug-Drug Interaction (DDI) Study for TQB3616Not yet recruitingPhase 1Chia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT06662773Written as TQB3616 capsule + rifampicin
- A Study To Evaluate The Effect Of Rifampicin Or Ltraconazole On Pharmacokinetics Of Ensartinib In Healthy VolunteersNot yet recruitingPhase 1Betta Pharmaceuticals Co., Ltd.NCT06492525Written as Rifampicin
See all 278 studies that test Rifampin →
Given in every arm · 22 — Rifampin is usual care beside what is tested
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT06192160Written as Rifampicin
- Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary DiseaseRecruitingPhase 4Bin CaoNCT07213765Written as Rifampicin (R)
- Short-term Bactericidal Effect of Contezolid in MAC-PDRecruitingPhase 4Bin CaoNCT07084402Written as Rifampicin (RIF)
- Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)CompletedPhase 2University of Massachusetts, WorcesterNCT04930744Written as Rifampicin
- A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's LymphomasTerminatedPhase 1CelgeneNCT02875223Written as Rifampicin
- The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.CompletedPhase 1Kyowa Kirin Co., Ltd.NCT02174250Written as Rifampin 300mg BID + istradefylline 40mg Day 8 only
- StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With TuberculosisCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT03882177Written as Rifafour
- Effects of Rifampicin and Probenecid On The Pharmacokinetic Profile Of Rongliflozin In Healthy SubjectsCompletedPhase 1Sunshine Lake Pharma Co., Ltd.NCT05497674Written as Rifampin
- A Study Of Oral PF-02341066, A C-Met/Hepatocyte Growth Factor Tyrosine Kinase Inhibitor, In Patients With Advanced CancerCompletedPhase 1PfizerNCT00585195Written as Rifampin
- Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in IndonesiaCompletedNot applicableUniversity of GiessenNCT02554318Written as Rifampicin
- Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid AcidStatus unknownPhase 1First Affiliated Hospital Xi'an Jiaotong UniversityNCT05297123Written as Realgar-Indigo naturalis formula
- Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic FibrosisCompletedNot applicableUniversity of Colorado, DenverNCT02372383Written as Rifampin
- Systematic Empirical vs. Test-guided Anti-TB Treatment Impact in Severely Immunosuppressed HIV-infected Adults Initiating ART With CD4 Cell Counts <100/mm3CompletedPhase 4ANRS, Emerging Infectious DiseasesNCT02057796Written as Rifampin, isoniazid, pyrazinamide, ethambutol
- Rosuvastatin Evaluation as a Tuberculosis Treatment AdjunctStatus unknownPhase 2National University Hospital, SingaporeNCT04504851Written as Rifampicin
- Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and MidazolamCompletedPhase 1BayerNCT03353857Written as Rifampicin
- Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected VolunteersTerminatedPhase 1University of Cape TownNCT03892161Written as Rifampicin 600mg QD tablet and DTG 50mg BD
- Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)CompletedPhase 2Johns Hopkins UniversityNCT01594827Written as Rifampin
- Essentiality of INH in TB TherapyCompletedPhase 2Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT01589497Written as Rifampicin
- Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS DesignCompletedPhase 2Michael HoelscherNCT01785186Written as Rifampicin
- Evaluating Celecoxib Activity in Mycobacterium Tuberculosis: A Whole Blood Bactericidal Activity Study in Healthy VolunteersCompletedPhase 1National University Hospital, SingaporeNCT02602509Written as Rifampicin
Showing 20 of 22.
As the comparator · 48 — what is tested is compared with Rifampin
- All-Oral Fluoroquinolone-Based Triple Therapies for Adults With Imaging-Confirmed Osteoarticular BrucellosisNot yet recruitingNot applicableThe First Affiliated Hospital of Shihezi UniversityNCT07887152Written as Doxycycline + Rifampicin + Ceftriaxone (intravenous therapy for 4 weeks)
- Fluoroquinolone-Doxycycline Oral Treatments for Adults With Uncomplicated BrucellosisNot yet recruitingNot applicableThe First Affiliated Hospital of Shihezi UniversityNCT07887126Written as Doxycycline + Rifampicin
- Hypertonic Saline for MACRecruitingPhase 4Oregon Health and Science UniversityNCT04921943Written as Rifampin
- Platform Assessing Regimens and Durations In a Global Multisite Consortium for TBRecruitingPhase 2University College, LondonNCT06114628Written as Rifampicin (R)
- Efficacy & Safety of Fluoroquinolone-Based Brucellosis Regimens (BRUCE)Not yet recruitingNot applicableThe First Affiliated Hospital of Shihezi UniversityNCT07779629Written as Doxycycline + Rifampicin
- A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT07595042Written as Rifampin
- Shortened Regimen for Drug-susceptible TB in ChildrenRecruitingPhase 3Johns Hopkins UniversityNCT06253715Written as Rifampin
- A Novel Therapy With a 1-Month Ultrashort Regimen to Halt Progression From Latent Infection to Active Tuberculosis Among Close Contacts (The TB-YOUTH Study)RecruitingPhase 3Huashan HospitalNCT06022146Written as Rifampin and Isoniazid
- Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis MeningitisNot yet recruitingPhase 2BioVersys AGNCT07350174Written as HRZE
- A PAN-USR TB Multi-Center TrialRecruitingPhase 3Shenzhen Third People's HospitalNCT06905522Written as Rifampicin (R)
- Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible TuberculosisNot yet recruitingPhase 2Shanghai Pulmonary Hospital, Shanghai, ChinaNCT07129629Written as Rifampicin (R)
- Ultra-Short Regimen for Elderly DS-TBNot yet recruitingPhase 3Shenzhen Third People's HospitalNCT07076225Written as Rifampicin (R)
- Short-Course Anti-tuberculosis Regimens for Mild Spinal TuberculosisNot yet recruitingPhase 2Shandong UniversityNCT06917495Written as Rifampin
- Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney DiseaseNot yet recruitingPhase 4Miguel SantínNCT05021731Written as Rifampicin plus Isoniazid
- Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint InfectionRecruitingPhase 4Leiden University Medical CenterNCT06172010Written as Rifampicin and levofloxacin
- Sitafloxacin-containing Regimens for Shortening Tuberculosis TreatmentNot yet recruitingPhase 3First Affiliated Hospital of Zhejiang UniversityNCT05454345Written as Rifampin
- Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIRRecruitingPhase 3Tourcoing HospitalNCT04672525Written as Rifampicin
- Short-course Regimens for the Treatment of Pulmonary TuberculosisActive, not recruitingPhase 2/3Centers for Disease Control and PreventionNCT05766267Written as Rifampin
- Adjunctive Rifampin for the Treatment of Prosthetic Valve Endocarditis Due to S. AureusTerminatedPhase 3Todd C. Lee MD MPH FIDSANCT07253688Written as Rifampin
- 1HP Versus 3HR in the Treatment of Tuberculosis Infection in VietnamWithdrawnPhase 3Freundeskreis Für Internationale Tuberkulosehilfe e.VNCT06191692Written as Rifampicin
Showing 20 of 48.
Codes
What other systems call Rifampin · ClinicalTrials.gg INT008163
- MeSH (NLM) D012293RifampinConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) VJT6J7R4TRRIFAMPINConfirmed FDA, NLM
- RxNorm 9384One source FDA
- NCI Thesaurus C811RifampinOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D012293 | Rifampin | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | VJT6J7R4TR | RIFAMPIN | Confirmed FDA, NLM |
| RxNorm | 9384 | — | One source FDA |
| NCI Thesaurus | C811 | Rifampin | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.