Tuberculosis clinical trials
The registry lists 1,170 studies for Tuberculosis across more than 10 countries. 175 are recruiting or about to start. 766 of them are mainly about Tuberculosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 5 narrower conditions too, such as Tuberculosis, Pulmonary: 1,547 studies, 260 open.
ClinicalTrials.gov finds 1,672 studies for Tuberculosis. How that becomes 1,168 here
This page counts the studies the registry files under Tuberculosis, and those it files under no condition that list Tuberculosisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,672Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −376Filed under a narrower condition, counted on its own pageTuberculosis, Pulmonary 183 · Latent Tuberculosis 100 · Tuberculosis, Multidrug-Resistant 62 · Tuberculosis, Meningeal 21
- −31List Tuberculosis as a condition, but the registry did not file them under itMost often written as “Mycobacterium Tuberculosis” (3), “Intestinal Tuberculosis” (3), and “Extrapulmonary Tuberculosis” (3). The registry filed 1 of them under no condition at all, and the others under other conditions only, most often Tuberculosis, Extrapulmonary (5) and Crohn Disease (3).
- −97Match it another way35 name it in the title, 10 in a keyword, and 52 by a synonym or other text the search reads.
- 1,168The count on this page23 of them list Tuberculosis in their own words; the registry filed them under no condition.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (78) · University of Oxford (36) · Johns Hopkins University (26) · Global Alliance for TB Drug Development (26) · University of Cape Town (23) · Centers for Disease Control and Prevention (21) · Aeras (20) · GlaxoSmithKline (19)
What is being tested here
Drugs under test in Tuberculosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Isoniazid | 10 | 19 | 55 |
| Rifampin | 6 | 8 | 33 |
| Rifapentine | 6 | 10 | 26 |
| Moxifloxacin | 4 | 6 | 21 |
| Pyrazinamide | 4 | 5 | 20 |
| Acetylcysteine | 4 | 3 | 7 |
| Linezolid | 3 | 5 | 15 |
| Ethambutol | 3 | 5 | 13 |
| Atorvastatin | 3 | 2 | 4 |
| BCG Vaccine | 2 | 2 | 20 |
Drug classes tested here Statins 3 open · Integrase inhibitors 2 open · Corticosteroids 1 open · Hormonal contraceptives 1 open · Reverse transcriptase inhibitors 18
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients · Phase 3 · National Institute of Allergy and Infectious Diseases (NIAID)
- Dec 2026Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvac · Phase 3 · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
- Sep 2027Shortened Regimen for Drug-susceptible TB in Children · Phase 3 · Johns Hopkins University
- Nov 2026Pulmonary Rehabilitation Program in Patients With Post-Tuberculosis Lung Disease · Filantropia Hospital
- Nov 2026A Study to Investigate the Repeat-dose Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With Ganfeborole in Female Participants of Non-childbearing Potential · GlaxoSmithKline
- Nov 2026Effectiveness of Psychosocial Counseling in Patients With a New Tuberculosis Diagnosis · Universitas Diponegoro
- Dec 2026First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b · Statens Serum Institut
- Dec 2026Prednisolone for 12 Versus 6 Months to Treat Pulmonary Sarcoidosis · Post Graduate Institute of Medical Education and Research, Chandigarh
- Dec 2026Sputum-free Diagnostis of TB · Research Center Borstel
- Dec 2026PRecision biomArker-Guided MAnagement of TuberculosIs Contacts: a Discrete Choice Experiment · University College, London
Who these studies take
Of the 109 Tuberculosis studies recruiting now, 64 (59%) set no upper age limit and 35 (32%) stop at 75 or younger. 48 (44%) take children under 18. 3 (3%) are for women only and 2 (2%) for men only; 30 (28%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 25 (23%) | 25 (23%) |
| 18 | 88 (81%) | 87 (80%) |
| 30 | 90 (83%) | 89 (82%) |
| 40 | 91 (83%) | 90 (83%) |
| 50 | 91 (83%) | 90 (83%) |
| 65 | 87 (80%) | 88 (81%) |
| 75 | 75 (69%) | 76 (70%) |
| 85 | 70 (64%) | 71 (65%) |
Across all 1,170 studies, recruiting or not: 41% stop at 75 or younger and 38% at 65; 34% take children; 2% are for women only and 3% for men only; 34% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tuberculosis studies take
Of 63 phase 2 interventional studies under Tuberculosis, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 10 mo3–25 · 59 studies | — | 13 mo3–30 · 40 studies |
| Phase 1/2 | 39 mo25–53 · 18 studies | — | — |
| Phase 2 | 24 mo15–36 · 63 studies | — | 24 mo15–37 · 43 studies |
| Phase 3 | 55 mo38–76 · 40 studies | — | 54 mo38–67 · 33 studies |
| Phase 4 | 36 mo26–47 · 22 studies | — | — |
| Interventional, no phase | 25 mo14–41 · 171 studies | — | 25 mo15–41 · 169 studies |
| Observational | 36 mo21–76 · 134 studies | — | 41 mo24–76 · 122 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting3
- Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial)Oct 26, 2026NCT07163143
- ID93/GLA-SE Vaccination + BCG ChallengeOct 22, 2026NCT06670755
- A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIVOct 19, 2026NCT07124559
Newly registered6
- Spatiotemporal Modeling of Tuberculosis Transmission Risk in a Clinical Waiting Room Using Environmental and Patient Movement Data: Impact of Simple Patient Management InterventionsNov 10, 2026NCT07927881
- Single-session High-Intensity Laser Therapy in Pulmonary TuberculosisNov 9, 2026NCT07925138
- Biomarker Analysis for Diagnosing and Treatment Monitoring in Extrapulmonary Tuberculosis Patients in Nairobi, KenyaOct 28, 2026NCT07901387
- Effect of Vitamin D and Zinc Supplementation on Inflammatory Biomarkers in Pulmonary Tuberculosis PatientsOct 27, 2026NCT07899138
- BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in ChildrenOct 26, 2026NCT07893444
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Studies
Recruiting first, then most recently updated. Showing 50 of 1,170. Browse all 1,170 → or search them.
- Training Protocol on the Natural History of TuberculosisRecruitingNCT012120031 country
- Fibroblast Activating Protein (FAP) PET/CT in Adults With TuberculosisRecruitingNCT07830771Early Phase 11 country
- Pulmonary Rehabilitation in African CountriesNot yet recruitingNCT07602673Not applicable3 countries
- Rapid Research in Diagnostics Development for TB NetworkRecruitingNCT04923958Not applicable8 countries
- Re-evaluating the Duration in Children of TB TreatmentNot yet recruitingNCT07656012Phase 21 country
- A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIVRecruitingNCT07124559Phase 1/26 countries
- Paradoxical Tuberculosis Reactions in Patients Without HIV InfectionRecruitingNCT040520222 countries
- Evaluating the Safety and Immunogenicity of MTBVACRecruitingNCT05947890Phase 21 country
- Biomarker Analysis for Diagnosing and Treatment Monitoring in Extrapulmonary Tuberculosis Patients in Nairobi, KenyaRecruitingNCT079013871 country
- Evaluation of New TB Diagnostic Tests (NATs) in PakistanEnrolling by invitationNCT06984887Not applicable1 country
- Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial)RecruitingNCT07163143Phase 33 countries
- BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in ChildrenRecruitingNCT07893444Phase 21 country
- ID93/GLA-SE Vaccination + BCG ChallengeRecruitingNCT06670755Not applicable1 country
- Silymarin Versus N-Acetylcysteine as Protective Effect Against Anti-tuberculosis Drugs Induced Liver Injury.Not yet recruitingNCT07875322Early Phase 11 country
- Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)RecruitingNCT05989802Not applicable3 countries
- Diagnostic Innovations for Pediatric Tuberculosis in BoliviaRecruitingNCT061138611 country
- Screening With Portable X-rays for Rapid Recognition of TBRecruitingNCT07737275Not applicable1 country
- A Study to Investigate the Repeat-dose Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With Ganfeborole in Female Participants of Non-childbearing PotentialRecruitingNCT07784894Phase 11 country
- Systems Analysis and Improvement Approach to Prevent TBEnrolling by invitationNCT06314386Not applicable1 country
- Evaluation and Demonstration of New Tuberculosis Diagnostics for IndonesiaRecruitingNCT07293455Not applicable1 country
- Integrating Tuberculosis Treatment Into Community Pharmacies to Improve TB/HIV Outcomes in UgandaNot yet recruitingNCT07840651Not applicable1 country
- Effectiveness of Chat-based Mobile Application for Consultation (Zalo) in Improving Compliance With Follow-up Tests After Abnormal Chest X-ray Findings Interpret by Artificial IntelligentRecruitingNCT07234929Not applicable1 country
- rBCG-N-RSV Vaccine in Adults Aged 60 Years and OlderRecruitingNCT07762014Phase 21 country
- A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy AdultsNot yet recruitingNCT07818824Phase 11 country
- Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB TreatmentRecruitingNCT06497465Phase 31 country
- Latent Infection Freshmen Tracking for TuberculosisRecruitingNCT07811518Phase 41 country
- South Africa Smoking Cessation and Engagement in HIV/TB Care CareRecruitingNCT05842161Not applicable1 country
- Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory TrialRecruitingNCT07118059Phase 21 country
- Effects of Tuberculosis Infection on Development and Function of the PlacentaRecruitingNCT063529701 country
- Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA in Hong KongRecruitingNCT066462371 country
- Program for Rifampicin-Resistant Disease With Stratified Medicine for TuberculosisRecruitingNCT06441006Phase 2/35 countries
- Assessing Diagnostics At Point-of-care for TuberculosisRecruitingNCT05941052Not applicable3 countries
- Kulindana: Community-friendly Delivery and Monitoring of TPT to Improve Uptake and Reduce TB TransmissionRecruitingNCT07628140Not applicable1 country
- A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 216 countries
- Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TBRecruitingNCT07672405Phase 22 countries
- Incidence of Tuberculosis in Patients With Autoimmune Rheumatic DiseasesNot yet recruitingNCT07731672Not applicable1 country
- Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in ChildrenEnrolling by invitationNCT07240259Not applicable1 country
- Effects of the Active Cycle of Breathing Technique With and Without Balloon Blowing Therapy in TuberculosisRecruitingNCT07484490Not applicable1 country
- Short Course Regimen in Low Risk Active Tuberculosis- a Multicenter, Randomized, Active-controlled, TrialRecruitingNCT06727864Phase 31 country
- Digital Psychosocial Interventions on Stigma and Health Outcomes in TB PatientsNot yet recruitingNCT07742683Not applicable
- A Step Forward for Unraveling the Immune Mechanisms and Tools for Tuberculosis Spectrum ManagementNot yet recruitingNCT07735754
- Mechanisms, Biomarkers and Pulmonary Rehabilitation in Post-TB Lung DiseaseNot yet recruitingNCT07731009Not applicable
- Shortened Regimen for Drug-susceptible TB in ChildrenRecruitingNCT06253715Phase 37 countries
- Advanced HIV Re-engagement in CareNot yet recruitingNCT07720128Not applicable1 country
- Candidate Clinical Correlate of Prognostic Outcome for TB StudyRecruitingNCT070180762 countries
- SCAF-TB - Saving Children and Their Families From Tuberculosis: Implementation Research to Improve TB Preventive Treatment Initiation and Completion Rates Among Contact Persons in Tajikistan and TanzaniaNot yet recruitingNCT07714707Not applicable2 countries
- A Phase I Study Investigating the Local Tolerability and Pharmacokinetics of Isoniazid (INH) Inhalation by Wet Nebulization in Patients With TuberculosisRecruitingNCT07708779Phase 11 country
- Pulmonary Rehabilitation Program in Patients With Post-Tuberculosis Lung DiseaseNot yet recruitingNCT07709507Not applicable
- A Novel Therapy With a 1-Month Ultrashort Regimen to Halt Progression From Latent Infection to Active Tuberculosis Among Close Contacts (The TB-YOUTH Study)RecruitingNCT06022146Phase 31 country
- Effectiveness of Psychosocial Counseling in Patients With a New Tuberculosis DiagnosisNot yet recruitingNCT07703696Not applicable1 country