Tuberculosis, Meningeal clinical trials
The registry lists 31 studies for Tuberculosis, Meningeal across more than 10 countries. 9 are recruiting or about to start. 29 of them are mainly about Tuberculosis, Meningeal (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Universitas Padjadjaran (4) · Oxford University Clinical Research Unit, Vietnam (4) · Beijing Chest Hospital (3) · ANRS, Emerging Infectious Diseases (2) · All India Institute of Medical Sciences, New Delhi (2) · Indian Council of Medical Research (1) · St George's, University of London (1) · University of Cape Town (1)
What is being tested here
Drugs under test in Tuberculosis, Meningeal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Sep 2027Intensified Short Course Regimen for TBM in Adults · Phase 3 · Indian Council of Medical Research
- Jun 2027Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis · ANRS, Emerging Infectious Diseases
- Aug 2027Clinical Characteristics, Treatment, Diagnostic Findings, and Outcomes of Tuberculous Meningitis in Indonesia, 2022-2025 · Ina-Respond
- Nov 2027Adjunctive Doxycycline for Central Nervous System Tuberculosis · National University Hospital, Singapore
Who these studies take
Of the 6 Tuberculosis, Meningeal studies recruiting now, 6 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (17%) | 1 (17%) |
| 18 | 5 (83%) | 5 (83%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 6 (100%) | 6 (100%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 6 (100%) | 6 (100%) |
Across all 31 studies, recruiting or not: 23% stop at 75 or younger and 19% at 65; 55% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Clinical Characteristics, Treatment, Diagnostic Findings, and Outcomes of Tuberculous Meningitis in Indonesia, 2022-2025RecruitingNCT079295191 country
- BPaLMZ for TB MeningitisRecruitingNCT07227779Phase 21 country
- Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous MeningitisRecruitingNCT04145258Phase 34 countries
- Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous MeningitisRecruitingNCT05383742Phase 212 countries
- Adjunctive Doxycycline for Central Nervous System TuberculosisRecruitingNCT06446245Phase 23 countries
- Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis MeningitisNot yet recruitingNCT07350174Phase 2
- Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitisRecruitingNCT05590455Phase 23 countries
- Phase II Clinical Study of Contezolid for the Treatment of Tuberculous MeningitisEnrolling by invitationNCT06811025Phase 1/21 country
- Intensified Short Course Regimen for TBM in AdultsNot yet recruitingNCT05917340Phase 31 country
- Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous MeningitisCompletedNCT043089281 country
- Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous MeningitisCompletedNCT03100786Phase 31 country
- Intrathecal Therapy for Adult Tuberculous Meningitis: Impact on Clinical OutcomesCompletedNCT06811792
- Adjunctive Linezolid for the Treatment of Tuberculous MeningitisCompletedNCT04021121Phase 21 country
- Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)CompletedNCT03092817Phase 32 countries
- Pharmacokinetic Study of Linezolid for TB MeningitisCompletedNCT03537495Phase 21 country
- Xpert MTB/RIF Assay for Diagnosis of Tuberculous Meningitis (TBM) in Maharaj Nakorn Chiang Mai HospitalCompletedNCT05781646Not applicable
- Diagnostic Accuracy of Imaging Findings in TBM/Spinal Tubercular Arachnoiditis and Correlation With OutcomesStatus unknownNCT056362541 country
- Driving Reduced AIDS-associated Meningo-encephalitis MortalityCompletedNCT03226379Not applicable3 countries
- Optimizing Treatment to Improve TBM Outcomes in ChildrenCompletedNCT02958709Phase 1/22 countries
- Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBMCompletedNCT03927313Phase 21 country
- Optimizing Antituberculosis Therapy in Adults With Tuberculous MeningitisStatus unknownNCT03787940Not applicable1 country
- Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS TuberculosisStatus unknownNCT04620772Phase 2/3
- Retrospective Real-word Study of Linezolid for the Treatment of Tuberculous MeningitisStatus unknownNCT038986351 country
- High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding StudyCompletedNCT02169882Phase 2/31 country
- A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous MeningitisCompletedNCT02237365Phase 21 country
- The Relationships Between Gene Polymorphisms of LTA4H and Dexamethasone Treatment for Tuberculous MeningitisStatus unknownNCT02588196Phase 4
- Diagnosis of Tuberculous Meningitis by ESAT-6 in CSFCompletedNCT013719161 country
- Rifampicin Explorative PK Study for Tuberculous Meningitis Comparing Oral and Intravenous PreparationCompletedNCT01802502Phase 21 country
- Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability StudyCompletedNCT01158755Phase 21 country
- Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive DexamethasoneCompletedNCT01317654
- Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous MeningitisStatus unknownNCT00433719Not applicable1 country