An observational study in Tuberculosis (TB), sponsored by Centre for Infectious Disease Research in Zambia. Completed at 1 site in Zambia. Open to participants aged Up to 99 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by Centre for Infectious Disease Research in Zambia · Observational
To establish a novel approach for estimating the risk of TB transmission in a healthcare clinic in a high TB/HIV setting in Zambia using data on patient characteristics, indoor CO2 and bioaerosol measurements, and patient flows from video sensors.
The proposed study has an observational design, employing exposure assessment methods and implements interventions targeting patient flow. Briefly, we will collect patient-related information (anonymous patient tracking, clinical patient information) and environmental data (CO2 levels, particle concentrations) in Kanyama first level hospital in Lusaka, Zambia, over a period of 6 weeks for approximately 6 hours per day.
1,170 studies on the registry are indexed under Tuberculosis; 175 are open to participants now.
This study's enrollment of 1,000 is above the median of 253 across 317 observational studies indexed under Tuberculosis.
Browse Tuberculosis studies →Centre for Infectious Disease Research in Zambia is the lead sponsor of 41 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All attending the selected clinics will be included
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Exclusion Criteria:
Patient flow, clustering, occupancy, CO₂, particles, bioaerosols and clinical/epidemiological characteristics.
Estimated TB transmission risk will be calculated using a spatiotemporal model incorporating environmental conditions and patient movement/occupancy data. The outcome will be summarized as the change in modeled transmission-risk estimates between the pre-intervention and intervention periods.
Time frame: 6 MONTHS
TB TRANSMISSION
We aim to establish a novel approach for estimating the risk of TB transmission in a healthcare clinic in a high TB/HIV setting in Zambia using data on patient characteristics, indoor CO₂ and bioaerosol measurements, and patient flows from video sensors. We will use these data to parameterise a novel mathematical model of TB transmission in primary care clinics, identify the drivers of transmission risk, and estimate the impact of interventions targeting patient flows on the risk of TB transmission.
Time frame: 6 MONTHS
TB TRANSMISSION
To determine patient flow, patient clustering, and the number of patients at a given time point using anonymous video sensors and environmental data (CO₂ levels, particle concentrations, bioaersol), as well as to study clinical features and to study epidemiological and clinical characteristics of patients seen at the outpatient department, such as TB/HIV suspicion, using clinical information from medical records.
Time frame: 6 months
Ran from Mar 2024 to primary completion in Aug 2024, 4 months.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Centre for Infectious Disease Research in Zambia