Drug
Ethambutol clinical trials
Also written Myambutol.
- studies test it
- 30
- open now
- 3
- in phase 3
- 11
- first study started
- 1994
Keep track of what changes. Save the Ethambutol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Studies by the year they started
26 studies that test it; most in 2023 (4)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2006 | 1 |
| 2008 | 1 |
| 2010 | 1 |
| 2011 | 1 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 2 |
| 2016 | 2 |
| 2017 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 4 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 2
- Phase 2
- 10
- Phase 3
- 11
- Phase 4
- 6
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 23
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Centers for Disease Control and Prevention (2) · University College, London (2) · Pharmacia (2) · University of Cape Town (1) · GlaxoSmithKline (1) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Tuberculosis Research Centre, India (1)
Often tested with
Tested in the same studies.
Rifampin (19) · Pyrazinamide (18) · Isoniazid (18) · Levofloxacin (4) · Clofazimine (4) · Moxifloxacin (3) · Bedaquiline (3) · Azithromycin (3)
Studies
Open first, then newest update. How each study uses Ethambutol is read from its arms, and is right about nine times in ten.
Testing it · 30
- Re-evaluating the Duration in Children of TB TreatmentNot yet recruitingPhase 2University of Wisconsin, MadisonNCT07656012Written as Ethambutol
- PanACEA - STEP2C -01RecruitingPhase 2Michael HoelscherNCT05807399Written as Ethambutol (E)
- Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial)Not yet recruitingPhase 3University College, LondonNCT07163143Written as Ethambutol (E)
- Tuberculosis Treatment Shortening TrialCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00130247Written as Ethambutol
- Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of TuberculosisCompletedPhase 3Centers for Disease Control and PreventionNCT02563327Written as Ethambutol
- Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and PyrazinamideSuspendedPhase 2University Hospital, LinkoepingNCT04694586Written as HRZE
- Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary TuberculosisCompletedPhase 2GlaxoSmithKlineNCT05382312Written as RIFAFOUR e-275
- Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary TuberculosisTerminatedPhase 2Gates Medical Research InstituteNCT05971602Written as Isoniazid, Rifampicin, Pyrazinamide, Ethambutol (HRZE)
- Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated TuberculosisActive, not recruitingPhase 3University of Cape TownNCT04951986Written as Rifampicin, Pyrazinamide, Ethambutol and Isoniazid
- Evaluating the Early Bactericidal Activity, Safety and Tolerability of Nebulised RESP301 in Adults With TuberculosisTerminatedPhase 2Thirty Respiratory LimitedNCT06041919Written as HRZE
- REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) TreatmentCompletedPhase 4Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT01380080Written as Rifampin/isoniazid/pyrazinamide/ethambutol FDC
- Preventive Therapy for Tuberculosis in HIV Infected PersonsCompletedPhase 3Tuberculosis Research Centre, IndiaNCT00351702Written as Isoniazid with Ethambutol
- Using Biomarkers to Predict TB Treatment DurationCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT02821832Written as Isoniazid, Rifampicin, Pyrazinamide and Ethambutol
- A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy ParticipantsCompletedPhase 1Spero TherapeuticsNCT05966688Written as Ethambutol
- The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TBCompletedPhase 3IUATLD, IncNCT02409290Written as Ethambutol
- Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for Drug-sensitive TuberculosisCompletedPhase 2/3University College, LondonNCT03474198Written as Ethambutol
- A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.CompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000641Written as Ethambutol hydrochloride
- Phase II Investigation of Antimycobacterial Therapy on Progressive, Pulmonary SarcoidosisCompletedPhase 2Vanderbilt UniversityNCT02024555Written as Ethambutol
- PK Study of Anti-TB DrugsCompletedPhase 1University of OxfordNCT02457208Written as Ethambutol (E)
- Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary TuberculosisCompletedPhase 3Global Alliance for TB Drug DevelopmentNCT00864383Written as Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin
See all 30 studies that test Ethambutol →
Given in every arm · 23 — Ethambutol is usual care beside what is tested
- Finding the Optimal Regimen for Mycobacterium Abscessus TreatmentRecruitingPhase 2/3The University of QueenslandNCT04310930Written as Ethambutol
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform TrialNot yet recruitingPhase 2The University of QueenslandNCT07485010Written as Ethambutol
- CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung InfectionsRecruitingPhase 3Centre Hospitalier Universitaire, AmiensNCT03236987Written as Ethambutol
- Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary DiseaseRecruitingPhase 4Bin CaoNCT07213765Written as Ethambutol (E)
- Short-term Bactericidal Effect of Contezolid in MAC-PDRecruitingPhase 4Bin CaoNCT07084402Written as Ethambutol
- Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)CompletedPhase 2University of Massachusetts, WorcesterNCT04930744Written as Ethambutol
- Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST StudyTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT04311502Written as Ethambutol
- A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)CompletedPhase 2/3Janssen Pharmaceutical K.K.NCT04630145Written as Ethambutol
- Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium ComplexCompletedPhase 3Insmed IncorporatedNCT04677569Written as Ethambutol
- Comparison of Two- Versus Three-antibiotic Therapy for Pulmonary Mycobacterium Avium Complex DiseaseCompletedPhase 2/3Kevin WinthropNCT03672630Written as Ethambutol
- Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium ComplexCompletedPhase 3Insmed IncorporatedNCT04677543Written as Ethambutol
- StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With TuberculosisCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT03882177Written as Rifafour
- A Randomised Trial to Evaluate Toxicity and Efficacy of 1200mg and 1800mg Rifampicin for Pulmonary TuberculosisCompletedPhase 3St George's, University of LondonNCT02581527Written as Ethambutol
- Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in IndonesiaCompletedNot applicableUniversity of GiessenNCT02554318Written as Ethambutol
- Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic FibrosisCompletedNot applicableUniversity of Colorado, DenverNCT02372383Written as Ethambutol
- Systematic Empirical vs. Test-guided Anti-TB Treatment Impact in Severely Immunosuppressed HIV-infected Adults Initiating ART With CD4 Cell Counts <100/mm3CompletedPhase 4ANRS, Emerging Infectious DiseasesNCT02057796Written as Rifampin, isoniazid, pyrazinamide, ethambutol
- Rosuvastatin Evaluation as a Tuberculosis Treatment AdjunctStatus unknownPhase 2National University Hospital, SingaporeNCT04504851Written as Ethambutol
- Multicenter, Randomized Study Evaluating the Value of Antitubercular Treatment During Recurent Anterior Uveitis (URBA)Status unknownPhase 3Assistance Publique - Hôpitaux de ParisNCT04117698Written as Ethambutol
- Essentiality of INH in TB TherapyCompletedPhase 2Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT01589497Written as Ethambutol
- Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIVTerminatedPhase 2Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT01601626Written as Ethambutol
Showing 20 of 23.
As the comparator · 38 — what is tested is compared with Ethambutol
- Hypertonic Saline for MACRecruitingPhase 4Oregon Health and Science UniversityNCT04921943Written as Ethambutol
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT06192160Written as Ethambutol
- Platform Assessing Regimens and Durations In a Global Multisite Consortium for TBRecruitingPhase 2University College, LondonNCT06114628Written as Ethambutol (E)
- A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT07595042Written as Ethambutol
- Shortened Regimen for Drug-susceptible TB in ChildrenRecruitingPhase 3Johns Hopkins UniversityNCT06253715Written as Ethambutol
- Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous MeningitisRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05383742Written as ethambutol (EMB)
- Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis MeningitisNot yet recruitingPhase 2BioVersys AGNCT07350174Written as HRZE
- A PAN-USR TB Multi-Center TrialRecruitingPhase 3Shenzhen Third People's HospitalNCT06905522Written as Ethambutol (E)
- Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible TuberculosisNot yet recruitingPhase 2Shanghai Pulmonary Hospital, Shanghai, ChinaNCT07129629Written as Ethambutol (E)
- Ultra-Short Regimen for Elderly DS-TBNot yet recruitingPhase 3Shenzhen Third People's HospitalNCT07076225Written as Ethambutol (E)
- Short-Course Anti-tuberculosis Regimens for Mild Spinal TuberculosisNot yet recruitingPhase 2Shandong UniversityNCT06917495Written as Ethambutol
- Intensified Short Course Regimen for TBM in AdultsNot yet recruitingPhase 3Indian Council of Medical ResearchNCT05917340Written as HRZE
- Sitafloxacin-containing Regimens for Shortening Tuberculosis TreatmentNot yet recruitingPhase 3First Affiliated Hospital of Zhejiang UniversityNCT05454345Written as Ethambutol
- Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3)Not yet recruitingPhase 3Seoul National University HospitalNCT04485156Written as Ethambutol
- Short-course Regimens for the Treatment of Pulmonary TuberculosisActive, not recruitingPhase 2/3Centers for Disease Control and PreventionNCT05766267Written as Ethambutol
- BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)CompletedPhase 1/2Michael HoelscherNCT04044001Written as Rifafour e-275®
- Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult PatientsCompletedPhase 2/3Global Alliance for TB Drug DevelopmentNCT03338621Written as HRZE
- Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TBCompletedPhase 2Otsuka Pharmaceutical Development & Commercialization, Inc.NCT05221502Written as RHEZ
- Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TuberculosisActive, not recruitingPhase 2Brigham and Women's HospitalNCT05556746Written as Ethambutol (EMB)
- Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary TuberculosisActive, not recruitingPhase 2Global Alliance for TB Drug DevelopmentNCT06058299Written as HRZE
Showing 20 of 38.
Codes
What other systems call Ethambutol · ClinicalTrials.gg INT007451
- MeSH (NLM) D004977EthambutolConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 8G167061QZETHAMBUTOLConfirmed FDA, NLM, Wikidata
- RxNorm 4110Confirmed FDA, Wikidata
- Wikidata Q27106530ethambutol dihydrochlorideConfirmed FDA, NLM, Wikidata
- Wikidata Q412318ethambutolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61755EthambutolOne source FDA
- DrugBank DB00330One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004977 | Ethambutol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 8G167061QZ | ETHAMBUTOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4110 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27106530 | ethambutol dihydrochloride | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q412318 | ethambutol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61755 | Ethambutol | One source FDA |
| DrugBank | DB00330 | — | One source Wikidata |
Also registered as ethambutol hydrochloride (UNII QE4VW5FO07 · RxNorm 142435).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.