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Tic Disorders clinical trials

The registry lists 102 studies for Tic Disorders across more than 10 countries. 26 are recruiting or about to start. 23 of them are mainly about Tic Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Tourette Syndrome too: 267 studies, 54 open.

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Status

Completed
61
Recruiting
19
Status unknown
9
Not yet recruiting
6
Terminated
2
Withdrawn
2

Phase

Phase 3
10
Phase 2
9
Phase 4
6
Phase 1
4

Where

United States
59
China
10
Canada
8
Italy
6
Hungary
5
Taiwan
5

Who runs them

National Institute of Neurological Disorders and Stroke (NINDS) (8) · Otsuka Pharmaceutical Development & Commercialization, Inc. (5) · Yale University (5) · Children's Hospital of Fudan University (4) · Karolinska Institutet (4) · Washington University School of Medicine (3) · Johns Hopkins University (3) · National Institute of Mental Health (NIMH) (3)

What is being tested here

Drugs under test in Tic Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Sertraline101
Ornidazole101
Aripiprazole068
Ecopipam011
Ondansetron001
Nabiximols011
ABX-1431001
Cycloserine001
Acetylcysteine001
Alpha-tocotrienol quinone001

Drug classes tested here Antipsychotics 9

Coming up

1phase 3 study under way
6studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6

Who these studies take

Of the 19 Tic Disorders studies recruiting now, 4 (21%) set no upper age limit and 15 (79%) stop at 75 or younger. 14 (74%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (26%) take healthy volunteers.

Recruiting studies that take each age, of 19
AgeWomenMen
109 (47%)9 (47%)
1810 (53%)10 (53%)
308 (42%)8 (42%)
407 (37%)7 (37%)
507 (37%)7 (37%)
656 (32%)6 (32%)
754 (21%)4 (21%)
854 (21%)4 (21%)

Across all 102 studies, recruiting or not: 80% stop at 75 or younger and 79% at 65; 75% take children; 0% are for women only and 1% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Tic Disorders studies take

Of 39 interventional studies with no phase under Tic Disorders, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase28 mo16–64 · 39 studies—28 mo16–64 · 39 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 102. Browse all 102 → or search them.