ClinicalTrials.gg
Not yet recruitingNCT05874765Updated May 25, 2023

A Study of Prevalence and Clinical Characteristics of Tic Disorders in Children at Sohag University Hospital

An observational study in Tic Disorder, Childhood, sponsored by Sohag University. Not yet recruiting at 1 site in Egypt. Open to participants aged 3 Years to 18 Years. Per ClinicalTrials.gov, last updated 2023-05-25.

Sponsored by Sohag University · Observational

From the registry’s dates

  • Primary completion was expected by May 2024, 2 years 6 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
100
Ages
3 Years to 18 Years
Sex
All
01

Study summary

Tics are brief, sudden, repetitive movements and/or sounds that increase with stress, anxiety, transitions, or excitement.

Tics occur most commonly in children and adolescents, with boys more frequently affected than girls The American Academy of Child and Adolescent Psychiatry states that tics affect up to 10 percent of children during their early school years. .

The exact pathophysiologic mechanisms are unknown, but the disorders are likely to be due to disturbances of the cortico striatal- thalamo -circuitry. Risk factors for tic disorders include. Genetics: Tics tend to run in families, so there may be a genetic basis to these disorders. Sex: Men are more likely to be affected by tic disorders than women.

They are divided into motor tics (e.g., blinking, shrugging shoulders, grimacing, or jerking) and vocal tics (e.g., throat clearing, sniffing, grunting) .

Patients describe an inner urge or a local premonitory sensation, which is then relieved by performing the tic. The tic can be voluntarily suppressed for short periods of time. Tics increase with stress, anxiety, transitions, and excitement, and decrease with distraction.

The American Academy of Child and Adolescent Psychiatry states that tics affect up to 10 percent of children during their early school years .The most notable tic disorder is Tourette syndrome, in which both physical and verbal tics occur in the same individual, often at the same time. Transient tic disorder also involves both types of tics, but they often occur individually .

Tic disorders are classified into 3 categories : Transient tic disorders involve motor or vocal tics that last for more than 4 weeks but less than a year. Chronic tic disorders involve either motor tics or vocal tics (but not both) that last for more than a year. Tourette Syndrome, in which both physical and verbal tics occur in the same individual Conditions associated with tic disorders, especially in children with TS, include: anxiety, ADHD, depression ,autism ,spectrum disorder learning difficulties ,OCD speech and language difficulties, sleep difficulties other complications associated with tic disorders are related to the effect of the tics on self-esteem and self-image . Some research! has found that children with TS or any chronic tic disorder experience a lower quality of life and lower self-esteem than those without one of these conditions

02

Conditions studied

  • Tic Disorder, Childhood

Browse trials for

03

In context

Tic Disorders

102 studies on the registry are indexed under Tic Disorders; 26 are open to participants now.

This study's planned enrollment of 100 is above the median of 54 across 17 observational studies indexed under Tic Disorders.

Browse Tic Disorders studies →

Lead sponsor

Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
3 Years to 18 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

  • -Age between 3 and 18 years
  • All patients suffering from Tics and fulfill diagnostic criteria according to DSM V

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • -Age between 3 and 18 years
  • All patients suffering from Tics and fulfill diagnostic criteria according to DSM V

Exclusion criteria

Exclusion Criteria:

    • Patients with age below 3 years and after 18 years old
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)
Patient registry
No

Interventions

  • Diagnostic testDiagnostic and Statistical Manual of mental disorder- fifth edition ( DSM5)

    Diagnostic and Statistical Manual of mental disorder- fifth edition ( DSM5) , will be used to diagnose and classify the Tics among all included patients

06

What researchers measure

Primary outcomes

  1. Assessment of Tics severity will be by The Yale Global Tic Severity Scale ( Y G T S S-R)

    A clinician-rated instrument considerd as the gold standard for assessing tics in patients with Trourettes Syndrome and other tic disorders

    Time frame: 12 months

07

Study locations

1 site
08

References and documents

Publications

  • Leckman JF, Riddle MA, Hardin MT, Ort SI, Swartz KL, Stevenson J, Cohen DJ. The Yale Global Tic Severity Scale: initial testing of a clinician-rated scale of tic severity. J Am Acad Child Adolesc Psychiatry. 1989 Jul;28(4):566-73. doi: 10.1097/00004583-198907000-00015. PubMed 2768151 ↗
  • Barker A, Musso MW, Jones GN, Roid G, Gouvier D. Unreliable block span reveals simulated intellectual disability on the stanford-binet intelligence scales-fifth edition. Appl Neuropsychol Adult. 2014;21(1):51-9. doi: 10.1080/09084282.2012.726670. Epub 2013 Jun 21. PubMed 24826496 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Jun 2023; primary completion for May 2024, 11 months later.

How these figures are worked out, and which studies are left out of them.

Registered
May 16, 2023
First posted
May 25, 2023
StartEst.
Jun 2023
Primary completionEst.
May 2024
CompletionEst.
Jun 2024
Last update
May 25, 2023
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 25, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05874765
Lead sponsor
Sohag University
Responsible party
Esraa Ahmed Mohamed (Resident-pediatric department-sohag hospital university, Sohag University) — Principal investigator
First posted
May 25, 2023
Start date
Jun 2023 (estimated)
Primary completion
May 2024 (estimated)
Completion
Jun 2024 (estimated)
Last update
May 25, 2023

Study contacts

Esraa A Mohammed, resident
Contact
esraaahmed@med.sohag.edu.eg
01099711828
Montaser M Mohammed, professor
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2023. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion